Abstract: The contact lens (100) for augmented reality comprises: a transparent body (102) designed to be placed on an eye (104); and at least one augmented reality module comprising an optical source (114) attached to the transparent body (102) and designed to emit a light into the transparent body, and an optical element (116) attached to the transparent body (102) and designed to receive the light from the optical source (114) and send it in the direction of the eye (104). The optical element (116) is a hologram designed to diffract the received light as a holographic image in the direction of the eye (104).

Abstract: The present invention is in the field of bioluminescence in biology and/or medicine. In particular, the invention provides imidazopyrazine derivatives, processes for preparation thereof, and their uses as luciferins.

Abstract: The present invention relates to the use of type III polyketide synthases of bacteria, such as actinomycete bacteria, as phloroglucinol synthases. The present invention also relates to the isolated nucleic acid molecules encoding these type III polyketide synthases, and also to the vectors and the host cells comprising such nucleic acid molecules. The present invention also relates to methods for producing phloroglucinol.

Abstract: Various embodiments are directed to a system that utilizes regular expression (regex) to recognize at least portions of characters, words, text, numbers, etc. in a structured or unstructured dataset, any patterns associated therewith, and/or similarities between the determined patterns. In examples, a regex-based pattern recognition platform may receive a dataset and determine whether at least a first regex pattern and a second regex pattern can be identified. The occurrences of the first and second regex patterns and the frequency of those occurrences may reveal something about the dataset itself or any patterns contained therein.

Abstract: In one embodiment, a remote controller for a vehicle includes at least one control element for controlling operation of at least one aspect of the vehicle when the vehicle is in a remote-control mode; an actuator connected the at least one control element for controlling a position of the at least one control element when the vehicle is in an autonomous operations mode; and a processing system for receiving a first control signal from the vehicle indicative of a state of operation of the vehicle. In operation, the processing system generates a second control signal to the actuator to cause the actuator to control a position of the control element such that it corresponds to and indicates the state of operation of the vehicle.

Abstract: An aircraft includes an airframe with a thrust array attached thereto. The thrust array includes a plurality of propulsion assemblies that are independently controlled by a flight control system. A landing gear assembly is coupled to the airframe and includes a plurality of landing feet. An altitude sensor array includes a plurality of altitude sensors each of which is disposed within one of the landing feet such that when the aircraft is in the VTOL orientation, the altitude sensor array is configured to obtain multifocal altitude data relative to a landing surface. The flight control system is configured to generate a three-dimensional terrain map of the surface based upon the multifocal altitude data.

Abstract: In one embodiment, a remote controller for a vehicle includes at least one control element for controlling operation of at least one aspect of the vehicle when the vehicle is in a remote-control mode; an actuator connected the at least one control element for controlling a position of the at least one control element when the vehicle is in an autonomous operations mode; and a processing system for receiving a first control signal from the vehicle indicative of a state of operation of the vehicle. In operation, the processing system generates a second control signal to the actuator to cause the actuator to control a position of the control element such that it corresponds to and indicates the state of operation of the vehicle.

Abstract: In one embodiment, a remote controller for a vehicle includes at least one control element for controlling operation of at least one aspect of the vehicle when the vehicle is in a remote-control mode; an actuator connected the at least one control element for controlling a position of the at least one control element when the vehicle is in an autonomous operations mode; and a processing system for receiving a first control signal from the vehicle indicative of a state of operation of the vehicle. In operation, the processing system generates a second control signal to the actuator to cause the actuator to control a position of the control element such that it corresponds to and indicates the state of operation of the vehicle.

Abstract: An aircraft includes an airframe with a thrust array attached thereto. The thrust array includes a plurality of propulsion assemblies that are independently controlled by a flight control system. A landing gear assembly is coupled to the airframe and includes a plurality of landing feet. An altitude sensor array includes a plurality of altitude sensors each of which is disposed within one of the landing feet such that when the aircraft is in the VTOL orientation, the altitude sensor array is configured to obtain multifocal altitude data relative to a landing surface. The flight control system is configured to generate a three-dimensional terrain map of the surface based upon the multifocal altitude data.

Abstract: In one embodiment, a method is performed by a computer system in an aircraft. The method includes receiving an advance indication of a take-off or landing event to be executed by the aircraft in proximity to a landing area such that the landing area includes an arrangement of a plurality of emitters of electromagnetic radiation. The method further includes, responsive to the receiving, detecting, via a sensor in communication with the computer system, emission states of at least some of the plurality of emitters. In addition, the method includes transforming the detected emission states into an instruction set for the take-off or landing event. The method also includes initiating monitoring of the aircraft relative to the instruction set as the aircraft executes the take-off or landing event in proximity to the landing area.

Abstract: In one embodiment, a method is performed by a computer system in an aircraft. The method includes receiving an advance indication of a take-off or landing event to be executed by the aircraft in proximity to a landing area such that the landing area includes an arrangement of a plurality of emitters of electromagnetic radiation. The method further includes, responsive to the receiving, detecting, via a sensor in communication with the computer system, emission states of at least some of the plurality of emitters. In addition, the method includes transforming the detected emission states into an instruction set for the take-off or landing event. The method also includes initiating monitoring of the aircraft relative to the instruction set as the aircraft executes the take-off or landing event in proximity to the landing area.

Abstract: A pitot-static array system for a tail-sitting aircraft has a disk with a plurality of edge ports arrayed about an edge of the disk. Each of a plurality of pressure transducers is configured to measure air pressure at one of the edge ports. The edge ports are arrayed about an axis parallel to a pitch axis of the aircraft.

Abstract: A pitot-static array system for a tail-sitting aircraft has a disk with a plurality of edge ports arrayed about an edge of the disk. Each of a plurality of pressure transducers is configured to measure air pressure at one of the edge ports. The edge ports are arrayed about an axis parallel to a pitch axis of the aircraft.

Abstract: In one embodiment, a remote controller for a vehicle includes at least one control element for controlling operation of at least one aspect of the vehicle when the vehicle is in a remote-control mode; an actuator connected the at least one control element for controlling a position of the at least one control element when the vehicle is in an autonomous operations mode; and a processing system for receiving a first control signal from the vehicle indicative of a state of operation of the vehicle. In operation, the processing system generates a second control signal to the actuator to cause the actuator to control a position of the control element such that it corresponds to and indicates the state of operation of the vehicle.

Abstract: Disclosed is a method for assessing the prognosis of idiopathic membranous nephropathy in a body fluid sample from a human subject, based on profiling PLA2R1 epitopes recognized by autoantibodies in the sample. The method further relates to analysis of PLA2R1 epitope spreading amongst three PLA2R1 domains (Cys R, CTLD1 and CTLD7) that are recognized by anti-PLA2R1 autoantibodies, two of which (CTLD1 and CTLD7) are more closely associated with active idiopathic membranous nephropathy and likely linked by a mechanism of epitope spreading.

Abstract: One embodiment is an aircraft including at least one propulsion assembly; a cargo area for receiving payload to be transported by the aircraft; and a control system for determining characteristics of the received payload; automatically determining optimal control gains for operating the aircraft including the payload based on the determined payload characteristics; and providing control signals to at least one of the at least one propulsion assembly and a control assembly of the aircraft to control operation of the at least one propulsion assembly in accordance with the determined optimal control gains.

Abstract: In one embodiment, a method is performed by a computer system in an aircraft. The method includes receiving an advance indication of a take-off or landing event to be executed by the aircraft in proximity to a landing area such that the landing area includes an arrangement of a plurality of emitters of electromagnetic radiation. The method further includes, responsive to the receiving, detecting, via a sensor in communication with the computer system, emission states of at least some of the plurality of emitters. In addition, the method includes transforming the detected emission states into an instruction set for the take-off or landing event. The method also includes initiating monitoring of the aircraft relative to the instruction set as the aircraft executes the take-off or landing event in proximity to the landing area.

Abstract: The invention relates to a method for assessing the prognosis of idiopathic membranous nephropathy in a subject, based on the analysis of PLA2R1 epitope profile. The invention further relates to a method for monitoring the progression of idiopathic membranous nephropathy based on the analysis of the PLA2R1 epitope spreading. The invention highlights that three PLA2R1 domains (Cys R, CTLD1 and CTLD7) are involved in anti-PLA2R1 activity, with two of them (CTLD1 and CTLD7) more closely associated with active idiopathic membranous nephropathy and likely linked by a mechanism of epitope spreading.

Abstract: The present invention relates to therapeutic uses of human fibroblast growth factor 21 (FGF21) proteins.