Abstract: The invention describes kit of parts of polypeptides comprising: a) a peptide comprising: a1) an MHC class II T cell epitope or a CD1 d-restricted NKT cell epitope, and a2) immediately adjacent to said epitope or separated by at most 7 amino acids from said epitope a [CST]-X(2)-C [SEQ ID NO:7] or C-X(2)-[CST] [SEQ ID NO:8] oxidoreductase motif sequence, and b) a poly-peptide comprising: b1) a therapeutic protein and b2) the epitope defined in a1), wherein the epitope sequence is a sequence which differs from the sequence of the protein of b1). The therapeutic protein, in combination with the peptide, is used to prevent an immune response against the therapeutic protein.

Abstract: The present invention relates to methods of imaging template hybridisation for estimating cluster numbers prior to solid phase amplification and sequencing. More particularly, an initial round of imaging is carried out at the single molecule template hybridisation stage which allows a general estimation of cluster numbers prior to clusters being formed. Amplification of the signal allows single molecule imaging to be carried out using standard sequencing imaging apparatus.

Abstract: The invention relates to peptides such as HCPYCSLQPLALEGSLQKRG [SEQ ID NO: 26] and their use in the treatment of type 1 diabetes and the generation of cytolytic CD4+ T cell.

Abstract: One example method includes receiving, at a client device, an input to present data corresponding to an application. In response to the input, a first user interface for the application is displayed using a web browser on the client device. A streaming data service corresponding to data to be displayed is identified, the streaming data service hosted by a server. A first web worker thread corresponding to the web browser is used to subscribe to the streaming data service. New data corresponding to the streaming data service is obtained using the first web worker thread from the server, and provided to a second web worker thread corresponding to the web browser. The second web worker thread is used to process the new data and prepare for presentation on the first user interface.

Abstract: The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.

Abstract: A method for coating a turbomachine guide vane including a root and a tip, an extrados face and an intrados face connected to one another by a leading edge and a trailing edge, the method including completely covering one of the faces of the vane with a polymer coating of thickness (e1) provided with grooves, removing the grooves from a part of the polymer coating in such a way that the polymer coating includes a grooved zone and a non-grooved zone, coating the non-grooved zone with a coat of paint of thickness (e3) such that the thickness of the coat of paint superimposed on the non-grooved zone is substantially equal to the thickness (e1) of the grooved zone.

Abstract: A turbine engine extends along an axis (X) and includes a flow path of a primary flow (F1) that has a compressor, a combustion chamber, and a turbine. The turbine engine further includes an outflow region of a secondary flow (F2) that surrounds the primary path, a blower or a propeller located upstream of the primary path and the outflow region of the secondary flow (F2), at least one arm extending radially through the primary path, and at least one fluid circulation pipe extending inside the arm. The arm includes an inlet for air from the primary path so as to cool the fluid circulating in the pipe.

Abstract: A composite vane for a turbomachine, in particular an aircraft turbomachine, this vane including an aerofoil having a pressure side and a suction side connected together by a leading edge and by a trailing edge, the aerofoil been formed from a fibrous preform obtained by weaving fibres in three dimensions, which is embedded in a polymer matrix, the vane further including a first metal shield extending over and along the leading edge of the aerofoil, the vane further including at least one cover element extending over and along the trailing edge of the aerofoil.

Abstract: A turbojet engine, having a primary duct and a secondary duct surrounding the primary duct, a row of guide vanes extending in the secondary duct downstream of a fan, at least one servo extending in the secondary duct downstream of the guide vanes and housed in a profiled casing, and at least one air sampling scoop located in the region of the casing and equipped with a control valve. Where at least one guide vane located in the vicinity of the casing has a variable geometry zone, the geometry of which can be adjusted during operation.

Abstract: Turbines for an aircraft include a supply device of compressed air configured to supply compressed air to the aircraft, a cooling system of the compressed air supplied to the aircraft, having a scoop configured to collect cooling air in a flow duct of a secondary flow, and a management system configured to be supplied with the cooling air collected from the flow duct and configured to control radial clearances between a turbine casing and turbine rotor vanes tips. The management system is supplied with cooling air by the scoop of the cooling system.

Abstract: An optical module (10) is attached in front of an optical outlet (21) of a monostatic or quasi-monostatic laser rangefinder (20), for the purpose of transversely offsetting a laser beam of primary radiation (F) emitted by the optical outlet. In this manner, the risk of damage to an optical sensor (23) of the rangefinder can be avoided.

Abstract: A method for coating a turbomachine guide vane including a root and a tip, an extrados face and an intrados face connected to one another by a leading edge and a trailing edge, the method including completely covering one of the faces of the vane with a polymer coating of thickness (e1) provided with grooves, removing the grooves from a part of the polymer coating in such a way that the polymer coating includes a grooved zone and a non-grooved zone, coating the non-grooved zone with a coat of paint of thickness (e3) such that the thickness of the coat of paint superimposed on the non-grooved zone is substantially equal to the thickness (e1) of the grooved zone.

Abstract: A medical technology device for positioning and/or orientating an object relative to a patient while directly visualizing on the patient geometric information that is object-specific and relates to the object's position and/or orientation. The device includes a template that co-operates with the object to be positioned and/or to be oriented, and an optical marking unit that is coupled to the template in a specific position, for visualizing the object-specific geometric information.

Abstract: An optical module (10) is attached in front of an optical outlet (21) of a monostatic or quasi-monostatic laser rangefinder (20), for the purpose of transversely offsetting a laser beam of primary radiation (F) emitted by the optical outlet. In this manner, the risk of damage to an optical sensor (23) of the rangefinder can be avoided.

Abstract: A device for translating a scraper of droppings covering a corridor of a livestock building. The device includes a chain secured to the scraper, a first sprocket secured to a first end of the chain and a second sprocket secured to a second end of the chain. The first sprocket is rotated by a first motor and the second sprocket is rotated by a second motor in the opposite direction of the first sprocket. A controller controls power supply to the motors and takes states including: a driving state of the scraper in a first direction, wherein the first motor is supplied with power and the power supply of the second motor is cut off; and a driving state of the scraper in a direction opposite to the first direction, wherein the second motor is supplied with power and the power supply of the first motor is cut off.

Abstract: Turbines for an aircraft include a supply device of compressed air configured to supply compressed air to the aircraft, a cooling system of the compressed air supplied to the aircraft, having a scoop configured to collect cooling air in a flow duct of a secondary flow, and a management system configured to be supplied with the cooling air collected from the flow duct and configured to control radial clearances between a turbine casing and turbine rotor vanes tips. The management system is supplied with cooling air by the scoop of the cooling system.

Abstract: A driving sprocket for a marine-type chain whose links have a section of diameter between 8 and 20 millimeters, intended to be used in the agricultural field. The sprocket includes a main cylindrical recess between two lateral flanges and a plurality of regularly spaced forks projecting radially from the recess, delineating housings intended for receiving every other link of the substantially flat chain. The flanges extend beyond the recess over a height substantially equal to the width of a link of the chain.

Abstract: A driving sprocket for a marine-type chain whose links have a section of diameter between 8 and 20 millimeters, intended to be used in the agricultural field. The sprocket includes a main cylindrical recess between two lateral flanges and a plurality of regularly spaced forks projecting radially from the recess, delineating housings intended for receiving every other link of the substantially flat chain. The flanges extend beyond the recess over a height substantially equal to the width of a link of the chain.

Abstract: A device for translating a scraper of droppings covering a corridor of a livestock building. The device includes a chain secured to the scraper, a first sprocket secured to a first end of the chain and a second sprocket secured to a second end of the chain. The first sprocket is rotated by a first motor and the second sprocket is rotated by a second motor in the opposite direction of the first sprocket. A controller controls power supply to the motors and takes states including: a driving state of the scraper in a first direction, wherein the first motor is supplied with power and the power supply of the second motor is cut off; and a driving state of the scraper in a direction opposite to the first direction, wherein the second motor is supplied with power and the power supply of the first motor is cut off.

Abstract: A screwing equipment that comprises at least one rotary member mounted in a tool body and capable of producing at least one vibrational frequency representing a wear condition of said rotary member(s). Such screwing equipment further comprises means for measuring said vibrational frequencies designed to communicate with means for processing, said measurement enabling same to be compared to at least one reference frequency in order to determine said wear condition.