Abstract: Luminescent compositions are described comprising lanthanide-containing nanoclusters comprising lanthanide atoms bonded to at least one semimetal or transition metal via an oxygen or sulfur atom. Novel compositions include an antenna ligand complexed with the nanoclusters. The rare earth-metal nanoclusters are in the size range of 1 to 100 nm. Articles, such as solar cells, are described in which the nanoclusters (with or without antenna ligands) are dispersed in a polymer matrix. Novel methods of making luminescent films are also described.

Abstract: Luminescent compositions are described comprising lanthanide-containing nanoclusters comprising lanthanide atoms bonded to at least one semimetal or transition metal via an oxygen or sulfur atom. Novel compositions include an antenna ligand complexed with the nanoclusters. The rare earth-metal nanoclusters are in the size range of 1 to 100 nm. Articles, such as solar cells, are described in which the nanoclusters (with or without antenna ligands) are dispersed in a polymer matrix. Novel methods of making luminescent films are also described.

Abstract: Waveguide devices and schemes for fabricating waveguide devices useful in applications requiring modulation, attenuation, polarization control, and switching of optical signals are provided. In accordance with one embodiment of the present invention, a method of fabricating an integrated optical device is provided.

Abstract: In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a ?-donor conjugated to a ?-acceptor through a ?-electron conjugated bridge. In other aspects of the invention, donor structures and acceptor structures are provided. In another aspect of the invention, a chromophore-containing polymer is provided. In one embodiment, the chromophore is physically incorporated into the polymer to provide a composite. In another embodiment, the chromophore is covalently bonded to the polymer, either as a side chain polymer or through crosslinking into the polymer. In other aspects, the present invention also provides a method for making the chromophore, a method for making the chromophore-containing polymer, and methods for using the chromophore and chromophore-containing polymer.

Abstract: The invention is directed to a stable formulation of a biologically active protein useful for aerosol delivery to the respiratory tract of a patient in need of treatment comprising: (a) a carrier liquid comprising from about 10% to from about 100% V/V water and from about 0% to from about 90% V/V of an organic liquid; (b) a biologically effective amount of a protein suspended or dissolved in a carrier liquid; and (c) a stabilizing effective amount of a derivatized carbohydrate stabilizing agent suspended or dissolved in said carrier liquid. The stable formulations of the invention may optionally contain about 0.1% to about 5.0% W/V of a pharmaceutically acceptable excipient.

Abstract: Surfactants useful for enhancing the electrical conduction of electrodes attached to the surface of a patient. The surfactants are also useful in transport of materials in and out of the body of a patient (animal or human) and in the measurement of disease states. Typical surfactants particularly useful in the invention are broadly represented by protein/fatty acid based compounds. The protein/fatty acid compounds may be lipopolypeptides. In some embodiments the lipopolypeptides may be acyl peptides. Typical acyl peptides are Lamepon S™, MayTein C™ and MayTein CT™.

Abstract: The present invention provides both polymer systems and electrooptic (EO) chromophores that form the components of optical devices such as optical switches and other devices useful in an optical waveguide.

Abstract: Disclosed is a series of materials, which exhibit large birefringence under the influence of an applied electric field. These materials are capable of switching this large birefringence with a characteristic time on the order of 1 microsecond or less. In addition, these materials have good optical loss at this wavelength, and are stable under irradiation. These materials are suitable for fabrication of optical devices such a variable optical attenuators, switches, and modulators that respond in these time frames or slower. These materials are also suitable for use across a wide range of wavelengths. As a second component of this invention, some of these novel materials exhibit these desired optical properties (large birefringence, low loss, stability under illumination) at wavelengths as short as about 400 nm. These materials are suitable for fabrication of optical devices operating at or about 405 nm, where conventional EO materials strongly absorb and/or quickly degrade.

Abstract: According to the present invention, an improved waveguide device utilizes an advantageously designed optically functional cladding region and an associated modulation controller to address design challenges in applications requiring modulation, attenuation, control, switching, etc. of optical signals. In accordance with one embodiment of the present invention, an electrooptic modulator is provided comprising an optical waveguide, a cladding optically coupled to the optical waveguide, an optically functional cladding region defined in at least a portion of the cladding, and a modulation controller configured to provide a modulating control signal to the optically functional cladding region. The modulation controller is configured to generate an electric field in the optically functional region in response to a biased modulating RF control signal.

Abstract: A waveguide device is provided comprising an optical waveguide core and a cladding optically coupled to the optical waveguide core. The cladding comprises an optically functional region defining a refractive index that is configured to vary in response to a control signal applied to the optically functional region. The refractive index of the optically functional region is lower than the refractive index of the optical waveguide core. In accordance with one embodiment of the present invention, the optically functional region may be characterized as a Kerr Effect medium.

Abstract: Functional optical materials for optical systems that are typically useful in optical waveguides, optical switching systems, optical modulators, optical computing systems and the like. Included are polymer systems and electrooptical chromophores. Polymers are thermoplastic and/or thermosetting polymers and are blended or co-polymerized with the electrooptic chromophore. The thermoplastic or thermosetting polymer selected from an acrylic/methacrylic, polyester, polyurethane, polyimide, polyamide, epoxy resin, or hybrid (organic-inorganic) or nanocomposite polyester polymer. The electrooptic chromophore is selected from a substituted aniline, substituted azobenzene, substituted stilbene, or substituted imine. Methods for improving adhesion promotion for the various novel materials are also provided.

Abstract: This invention relates to a polymer electrolyte membrane comprising a proton conducting hydrocarbon-based polymer membrane, the polymer having a backbone and having acidic groups on side chains attached to the backbone. The invention also relates to a polymer electrolyte membrane comprising a proton conducting hydrocarbon-based polymer membrane having a phase separated morphological microstructure. The invention also relates to a polymer electrolyte membrane comprising a proton conducting membrane, the membrane comprising a basic material in combination with an acidic material selected from acidic hydrocarbon-based polymers, acidic hydrocarbon-based oligomers, and blends thereof.

Abstract: Functional optical materials for optical systems that are typically useful in optical waveguides, optical switching systems, optical modulators, optical computing systems and the like. Included are polymer systems and electrooptical chromophores. Polymers are thermoplastic and/or thermosetting polymers and are blended or co-polymerized with the electrooptic chromophore. Methods for improving adhesion promotion for the various novel materials are also provided.

Abstract: According to the present invention, an improved waveguide device utilizes an advantageously designed optically functional cladding region and an associated modulation controller to address design challenges in applications requiring modulation, attenuation, control, switching, etc. of optical signals. In accordance with one embodiment of the present invention, an electrooptic modulator is provided comprising an optical waveguide, a cladding optically coupled to the optical waveguide, an optically functional cladding region defined in at least a portion of the cladding, and a modulation controller configured to provide a modulating control signal to the optically functional cladding region. The modulation controller is configured to generate an electric field in the optically functional region in response to a biased modulating RF control signal.

Abstract: Waveguide devices and schemes for fabricating waveguide devices useful in applications requiring modulation, attenuation, polarization control, and switching of optical signals are provided. In accordance with one embodiment of the present invention, a method of fabricating an integrated optical device is provided.

Abstract: A waveguide device is provided comprising an optical waveguide core and a cladding optically coupled to the optical waveguide core. The cladding comprises an optically functional region defining a refractive index that is configured to vary in response to a control signal applied to the optically functional region. The refractive index of the optically functional region is lower than the refractive index of the optical waveguide core. In accordance with one embodiment of the present invention, the optically functional region may be characterized as a Kerr Effect medium. In accordance with 37 CFR 1.72(b), the purpose of this abstract is to enable the United States Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract will not be used for interpreting the scope of the claims.

Abstract: Surfactants useful for enhancing the electrical conduction of electrodes attached to the surface of a patient. The surfactants are also useful in transport of materials in and out of the body of a patient (animal or human) and in the measurement of disease states. Typical surfactants particularly useful in the invention are broadly represented by protein/fatty acid based compounds. The protein/fatty acid compounds may be lipopolypeptides. In some embodiments the lipopolypeptides may be acyl peptides. Typical acyl peptides are Lamepon S™, MayTein C™ and MayTein CT™.

Abstract: The invention is directed to a stable formulation of a biologically active protein useful for aerosol delivery to the respiratory tract of a patient in need of treatment comprising:

Abstract: A soft goods type foldable, wrappable sleeve orthopedic cast immobilizes and conforms to the shape and configuration of a limb, or other part of the anatomy. The soft-goods type cast assembly is initially specially formed or configured to specifically fit a selected portion of the anatomy of a patient. The cast conforms to the anatomy through the use of airtight and moisture-proof pouches which encapsulate either (1) open cell or fiberglass matrices impregnated with a water-activated hardenable pre-polymer, or (2) the entire assembly. After the tightening of the cast around the limb, the application of water activates the urethane polymer which conforms to the configuration of the limb encased. Supplemental bendable ribs may be employed to splint the limb prior to activation of the hardenable material. The soft goods type cast is held in place by straps, and may be removed or adjusted by releasing or tightening the straps. The splinting elements may be removed and replaced.

Abstract: Novel electrodeposited coating copolymer blends for a transfer process are disclosed enabling copolymers displaying high adhesion to metals, and which normally cannot be contact transferred, to be made readily transferable as thin continuous barrier films preferably 0.3 mil in thickness or less.