Patents by Inventor Vincent P. Pigiet

Vincent P. Pigiet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5028419
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with a sulfite or bisulfite compound.
    Type: Grant
    Filed: August 23, 1989
    Date of Patent: July 2, 1991
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet
  • Patent number: 4941885
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with thioglycolic acid compounds. This invention allows hair to be treated at a lower pH to minimize hair damage when waving, straightening, or softening the hair; when used to remove hair, objectionable odors of commercial depilatories are minimized or eliminated.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: July 17, 1990
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet
  • Patent number: 4935231
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with an organic reducing agent. This invention allows hair to be treated at a lower pH to minimize hair damage when waving, straightening, or softening the hair; when used to remove hair, objectionable odors of commercial depilatories are minimized or eliminated.
    Type: Grant
    Filed: January 4, 1988
    Date of Patent: June 19, 1990
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet
  • Patent number: 4919924
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with thioglycolic acid compounds. This invention allows hair to be treated at a lower pH to minimize hair damage when waving, straightening, or softening the hair; when used to remove hair, objectionable odors of commercial depilatories are minimized or eliminated.
    Type: Grant
    Filed: August 28, 1985
    Date of Patent: April 24, 1990
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet
  • Patent number: 4904602
    Abstract: The subject invention concerns a novel enzyme named thioredoxin shufflease, means for preparing the same, and procedures for using thioredoxin shufflease to fold proteins containing disulfide crosslinks. Thioredoxin shufflease is a generic term to define enzymes which have the following characteristics: (a) contain a single reactive thiol group; (b) catalyze the exchange of disulfides in a protein undergoing the refolding process; and (c) are not consumed in the oxidation/refolding process. Specifically exemplified is a thioredoxin shufflease produced from an E. coli thioredoxin gene.
    Type: Grant
    Filed: August 8, 1986
    Date of Patent: February 27, 1990
    Assignee: Repligen Corporation
    Inventors: Vincent P. Pigiet, James R. Rusche, Barbara J. Schuster
  • Patent number: 4894223
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with a sulfite or bisulfite compound.
    Type: Grant
    Filed: January 4, 1988
    Date of Patent: January 16, 1990
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet
  • Patent number: 4771036
    Abstract: The subject invention concerns a process for the prevention and reversal of cataracts. Specifically, the invention comprises the treatment of the eye lens with an effective cataract inhibiting amount of thioredoxin or thioredoxin-derived, or thioredoxin-like, dithiol peptide, alone, or in combination with a thioredoxin reductase regenerating system. The thioredoxin compound can be administered topically to a patient in need of such treatment on a daily basis over an extended period of time via known delivery techniques such as eye drops and ocular inserts.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: September 13, 1988
    Assignee: Trustees of Columbia University in the city of New York
    Inventors: Vincent P. Pigiet, Abraham Spector
  • Patent number: 4738841
    Abstract: The subject invention enables a more efficient management of hair by providing a novel preparation for waving, straightening, softening, or removing hair, employing as a key ingredient the compound thioredoxin or a thioredoxin-derived, or thioredoxin-like, dithiol peptide in combination with thioglycolic acid compounds. This invention allows hair to be treated at a lower pH to minimize hair damage when waving, straightening, or softening the hair; when used to remove hair, objectionable odors of commercial depilatories are minimized or eliminated.
    Type: Grant
    Filed: August 25, 1986
    Date of Patent: April 19, 1988
    Assignee: Repligen Corporation
    Inventor: Vincent P. Pigiet