Abstract: A method of selecting T cells with improved anti-cancer activity, the method including: a) quantifying glucose transporter 1 (GLUT1) expression level at the cell surface of a population of T cells by using a GLUT1 ligand, b) selecting T cells having a low GLUT1 expression level, wherein the T cells having a low GLUT1 expression level have improved anti-cancer activity. Also, a population of T cells with improved anti-cancer activity for use in the treatment of cancer, to the use of a GLUT1 ligand for selecting T cells with improved anti-cancer activity, and to the use of GLUT1 as a biomarker of the anti-cancer therapeutic efficacy of T cells.

Abstract: An optical fiber may comprise a core doped with one or more active ions to guide signal light from an input end of the optical fiber to an output end of the optical fiber, a cladding surrounding the core to guide pump light from the input end of the optical fiber to the output end of the optical fiber, and one or more inserts formed in the cladding surrounding the core. The core may have a geometry (e.g., a cross-sectional size, a helical pitch, and/or the like) that varies along a longitudinal length of the optical fiber, which may cause an absorption of the pump light to be modulated along the longitudinal length of the optical fiber.

Abstract: An adaptive radio frequency including an input, an output, at least one fixed passive inductor and at least one variable active inductor connected between the input and the output.

Abstract: Disclosed are methods for diagnosing CAT1-related diseases, wherein the methods include detecting CAT1 in a cell by a BLV.RBD ligand, or a variant or a fragment thereof. Also disclosed is a BLV.RBD ligand, or a variant or a fragment thereof for use in the treatment of CAT1-related diseases and/or BLV infections.

Abstract: A device for collecting, preserving and storing a sample of biological fluid comprising a porous medium for collecting and maintaining the membrane integrity of the eukaryotic cells contained in the sample, and their constituents is disclosed, the medium comprising at least 80% by weight of artificial components, advantageously at least 85%, preferably at least 90% of a total weight of the medium; and having a mean flow pore size (MFP) of at least 3 ?m.

Abstract: An optical fiber device may include a core including a primary section and a secondary section. The secondary section may include at least one insert element inserted within the primary section at an off-center location with respect to a center of the primary section. The secondary section may twist about an axis of the optical fiber device along a length of the optical fiber device. A rate of twist at which the secondary section twists about the axis may increase from a first end of the optical fiber device toward a second end of the optical fiber device. The secondary section being twisted about the axis may cause an optical beam, launched at the first end of the optical fiber device, to be at least partially converted to a rotary optical beam at the second end of the optical fiber device.

Abstract: An optical fiber may include a first core, a second core, and a cladding surrounding the first core and the second core. The second core may be at an off-center location with respect to a center of the optical fiber, or the second core may include an azimuthally nonuniform section at the off-center location. The second core may twist about an axis of the optical fiber along a length of the optical fiber, and the second core being twisted about the axis may cause an optical beam, launched into the second core at a first end of the optical fiber, to be at least partially converted to a rotary optical beam at a second end of the optical fiber.

Abstract: An optical fiber may comprise a core doped with one or more active ions to guide signal light from an input end of the optical fiber to an output end of the optical fiber, a cladding surrounding the core to guide pump light from the input end of the optical fiber to the output end of the optical fiber, and one or more inserts formed in the cladding surrounding the core. The core may have a geometry (e.g., a cross-sectional size, a helical pitch, and/or the like) that varies along a longitudinal length of the optical fiber, which may cause an absorption of the pump light to be modulated along the longitudinal length of the optical fiber.

Abstract: Methods for detecting and/or measuring the level of sodium-dependent multivitamin transporter (SMVT) in a biological sample. The methods include the steps of: (a) contacting the biological sample with a PERV-B.RBD ligand, a variant and/or a fragment thereof; and, detecting and/or measuring the binding of the PERV-B.RBD ligand, variant and/or fragment thereof to SMVT.

Abstract: An integrated solution strategy that integrates multiple domains together in a seamless and standardized way for increasing a user's control over facilities and equipment. This integrated approach can lead to a reduction of energy usage, more efficient energy usage, increased safety, health, and security of a facility and its occupants, optimized production in industrial settings, and associated and other economic advantages. Accurate, reliable information about a facility or equipment is essential to making timely, informed decisions. Enhanced automation provides a reliable means of collecting and assembling a variety of operating data and archiving that data into a central database for evaluation, reporting, forecasting, and negotiation with resource marketers.

Abstract: An optical fiber may comprise a core doped with one or more active ions to guide signal light from an input end of the optical fiber to an output end of the optical fiber, a cladding surrounding the core to guide pump light from the input end of the optical fiber to the output end of the optical fiber, and one or more inserts formed in the cladding surrounding the core. Each of the one or more inserts may have a geometry (e.g., a cross-sectional size, a helical pitch, and/or the like) that varies along a longitudinal length of the optical fiber, which may cause an absorption of the pump light to be modulated along the longitudinal length of the optical fiber.

Abstract: Disclosed is an in vitro method for assessing, evaluating, monitoring or predicting cell aging of a cell, wherein the method includes measuring the expression level of at least one cell surface nutrient transporter on the cell.

Abstract: An optical fiber may include a first core, a second core, and a cladding surrounding the first core and the second core. The second core may be at an off-center location with respect to a center of the optical fiber, or the second core may include an azimuthally nonuniform section at the off-center location. The second core may twist about an axis of the optical fiber along a length of the optical fiber, and the second core being twisted about the axis may cause an optical beam, launched into the second core at a first end of the optical fiber, to be at least partially converted to a rotary optical beam at a second end of the optical fiber.

Abstract: A method may include performing an active alignment to enable optical coupling between a first optical fiber and a second optical fiber via an imaging structure. An end of the first optical fiber may be at a first location on a first surface of the imaging structure. The first location may be a first transverse offset distance from an axis of the imaging structure. An end of the second optical fiber may be at a second location of the first surface of the imaging structure. The second location may be a second transverse offset distance from the axis of the imaging structure. The method may include fusion splicing the end of the first optical fiber at the first location on the first surface of the imaging structure, and fusion splicing the end of the second optical fiber at the second location on the first surface of the imaging structure.

Abstract: An optical fiber may comprise a core doped with one or more active ions to guide signal light from an input end of the optical fiber to an output end of the optical fiber, a cladding surrounding the core to guide pump light from the input end of the optical fiber to the output end of the optical fiber, and one or more inserts formed in the cladding surrounding the core. Each of the one or more inserts may have a geometry (e.g., a cross-sectional size, a helical pitch, and/or the like) that varies along a longitudinal length of the optical fiber, which may cause an absorption of the pump light to be modulated along the longitudinal length of the optical fiber.

Abstract: A device may splice, at a target splice point, a first end of a twisted fiber having a non-concentric core to an input end of a target fiber having a concentric core to form a spliced fiber wherein the concentric core of the target fiber and the non-concentric core of the twisted fiber have a particular offset at the target splice point. The device may taper at least a portion of the twisted fiber to form a tapered region of the spliced fiber and such that the particular offset at the target splice point corresponds to a pre-configured core offset wherein the target splice point is within the tapered region of the spliced fiber.

Abstract: An optical fiber device may include a unitary core including a primary section and a secondary section, wherein at least a portion of the secondary section is offset from a center of the unitary core, wherein the unitary core twists about an axis of the optical fiber device along a length of the optical fiber device, and wherein a refractive index of the primary section is greater than a refractive index of the secondary section; and a cladding surrounding the unitary core.

Abstract: A method may include performing an active alignment to enable optical coupling between a first optical fiber and a second optical fiber via an imaging structure. An end of the first optical fiber may be at a first location on a first surface of the imaging structure. The first location may be a first transverse offset distance from an axis of the imaging structure. An end of the second optical fiber may be at a second location of the first surface of the imaging structure. The second location may be a second transverse offset distance from the axis of the imaging structure. The method may include fusion splicing the end of the first optical fiber at the first location on the first surface of the imaging structure, and fusion splicing the end of the second optical fiber at the second location on the first surface of the imaging structure.

Abstract: An optical fiber device may include a core including a primary section and a secondary section. The secondary section may include at least one insert element inserted within the primary section at an off-center location with respect to a center of the primary section. The secondary section may twist about an axis of the optical fiber device along a length of the optical fiber device. A rate of twist at which the secondary section twists about the axis may increase from a first end of the optical fiber device toward a second end of the optical fiber device. The secondary section being twisted about the axis may cause an optical beam, launched at the first end of the optical fiber device, to be at least partially converted to a rotary optical beam at the second end of the optical fiber device.

Abstract: A device may splice, at a target splice point, a first end of a twisted fiber having a non-concentric core to an input end of a target fiber having a concentric core to form a spliced fiber wherein the concentric core of the target fiber and the non-concentric core of the twisted fiber have a particular offset at the target splice point. The device may taper at least a portion of the twisted fiber to form a tapered region of the spliced fiber and such that the particular offset at the target splice point corresponds to a pre-configured core offset wherein the target splice point is within the tapered region of the spliced fiber.