Patents by Inventor Vincent Ronfard

Vincent Ronfard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240261377
    Abstract: Provided are methods for repairing a wound or inducing the proliferative phase of a wound comprising administering a composition comprising a protease mixture comprising collagenases and a neutral protease to the wound in an amount effective for repair of wound tissue or for inducing the proliferative phase in the wound.
    Type: Application
    Filed: February 19, 2024
    Publication date: August 8, 2024
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Ira HERMAN, Vincent RONFARD, Lei SHI
  • Publication number: 20240263116
    Abstract: A tissue culture vessel including a graft support tray (200) and a box having a lid (400) and a base which engages and retains the tray. The tray has two operational states: a first operational state in which a floor of the tray is slightly raised with respect to a floor of the base and a second operational state in which the floor of said tray descends to contact the floor of the base.
    Type: Application
    Filed: June 20, 2022
    Publication date: August 8, 2024
    Inventors: Claude Nicolas Holenstein, Vincent Ronfard, Anna-Lena Dittrich, Siegfried Graf, Christian Beyer, Krzysztof Krasnopolski, Diane Ledroit, Gilles Weder, Roman Arnet, Noa Schmid, Charles Coen
  • Patent number: 11938173
    Abstract: Provided are methods for repairing a wound or inducing the proliferative phase of a wound comprising administering a composition comprising a protease mixture comprising collagenases and a neutral protease to the wound in an amount effective for repair of wound tissue or for inducing the proliferative phase in the wound.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: March 26, 2024
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Ira Herman, Vincent Ronfard, Lei Shi
  • Publication number: 20240026291
    Abstract: The invention relates to a device (1) for preparing a cell suspension comprising an enzyme reservoir (10), a first purification compartment (20) for receiving a first purification material (P1), wherein the first purification compartment (20) is in fluid connection or can be brought into fluid connection with the enzyme reservoir (10), a syringe (40) comprising a barrel (41) defining a barrel compartment (45) and a piston (42) which is movably arranged in the barrel compartment (45), wherein the syringe (40) comprises a syringe inlet (43) connected to the barrel compartment (45), wherein the syringe inlet (43) is in fluid connection or can be brought into fluid connection with the first purification compartment (20), and wherein the syringe (40) comprises a syringe outlet (44), and wherein the device (1) comprises a flow path from the enzyme reservoir (10) via the first purification compartment (20) to the syringe inlet (43). Also provided herein are methods for preparing a cell suspension.
    Type: Application
    Filed: December 1, 2021
    Publication date: January 25, 2024
    Applicant: CUTISS AG
    Inventors: Vincent RONFARD, Joaquin URDINEZ, Claude HOLENSTEIN
  • Publication number: 20230167498
    Abstract: The invention relates to methods of determining the phenotype of hair follicles. More specifically, the invention relates to a new method of determining the phenotype of a hair follicle by determining the expression profile of the cellular material attached to a plucked hair.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 1, 2023
    Applicant: HairClone Limited
    Inventors: Paul KEMP, Jennifer DILLON, Vincent RONFARD
  • Publication number: 20230114908
    Abstract: The invention relates to a fully disposable system for casting, polymerizing and compressing a hydrogel. The invention further relates to a method for producing a scaffold for the generation of artificial tissue products using said disposable system.
    Type: Application
    Filed: March 1, 2021
    Publication date: April 13, 2023
    Inventors: Claude Nicolas HOLENSTEIN, Jerry DONNAN, Vincent RONFARD
  • Publication number: 20230101666
    Abstract: The present invention relates to a device and method for automatically isolating viable cells from connective, epithelial or other tissue, and, if the tissue is multilayered, for automatically separating one tissue layer from another.
    Type: Application
    Filed: February 5, 2021
    Publication date: March 30, 2023
    Inventors: Claude Nicolas HOLENSTEIN, Vincent RONFARD, Anna-Lena DITTRICH, Reto FREI, Christian Stefan WULLSCHLEGER, Jascha EISENBERG, Sebastian WOLLMANN
  • Publication number: 20230000513
    Abstract: The present invention relates to a method for producing skin grafts for rehabilitation of skin defects, where the method is carried out in a closed system operated and controlled in an automated manner.
    Type: Application
    Filed: November 22, 2020
    Publication date: January 5, 2023
    Inventors: Vincent RONFARD, Claude HOLENSTEIN, Anna-Lena DITTRICH, Laurent BARNES, Reto FREI, Ulrich ÖFFINGER, Boris STOLZ
  • Publication number: 20220225969
    Abstract: The present invention relates to a device adapted to facilitate transport of a biopsy sample from a sterile extraction site to laboratory-type equipment by which the biopsy sample is processed, while maintaining the biopsy sample wetted and sterile and automatically transferring the biopsy sample from the device to the laboratory-type equipment.
    Type: Application
    Filed: June 3, 2020
    Publication date: July 21, 2022
    Inventors: Astrid Welti, Claude Holenstein, Vincent Ronfard, Anna-Lena Dittrich, Reto Frei, Christian Wullschleger, Sebastian Wollmann
  • Publication number: 20210379115
    Abstract: The invention in relates in part to a method for rejuvenating hair follicles, the method comprising the steps of: (1) obtaining androgen non-inhibited cells from hair follicle tissue; (2) culturing the androgen non-inhibited cells to produce an expanded population of androgen-non-inhibited cells; and (3) implanting the expanded population of androgen non-inhibited cells proximal to miniaturised and/or miniaturising hair follicles.
    Type: Application
    Filed: October 17, 2019
    Publication date: December 9, 2021
    Inventors: Paul KEMP, Vincent RONFARD
  • Publication number: 20170360904
    Abstract: Provided are methods for repairing a wound or inducing the proliferative phase of a wound comprising administering a composition comprising a protease mixture comprising collagenases and a neutral protease to the wound in an amount effective for repair of wound tissue or for inducing the proliferative phase in the wound.
    Type: Application
    Filed: December 10, 2015
    Publication date: December 21, 2017
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Ira HERMAN, Vincent RONFARD, Lei SHI
  • Patent number: 7824913
    Abstract: Cultured tissue constructs comprising cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention are prepared in defined media, that is, without the addition of chemically undefined components.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: November 2, 2010
    Assignee: Organogenesis, Inc.
    Inventors: Michael P. Murphy, Vincent Ronfard
  • Publication number: 20080108134
    Abstract: Cultured tissue constructs comprising cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention are prepared in defined media, that is, without the addition of chemically undefined components.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 8, 2008
    Applicant: Organogenesis, Inc.
    Inventors: Michael Murphy, Vincent Ronfard
  • Publication number: 20080009064
    Abstract: The invention relates to compositions and methods useful for cell culture in which cell adherence and release of cultured cells can be performed in a temperature-responsive manner.
    Type: Application
    Filed: July 6, 2007
    Publication date: January 10, 2008
    Inventors: Vincent Ronfard, Christopher O'Reilly
  • Publication number: 20070243158
    Abstract: The invention is directed to compositions containing growth agents synthesized from cultured cells from skin. Skin cells such as keratinocytes and dermal fibroblasts are cultured in vitro in cell medium and in the course of culture the cultured cells synthesize and secrete agents into the cell medium. The medium containing agents are collected and incorporated into pharmaceutical or cosmetic preparations to treat an individual. The preparation is applied and has a rejuvenating effect on the cells and tissue.
    Type: Application
    Filed: June 12, 2007
    Publication date: October 18, 2007
    Applicant: ORGANOGENESIS, INC.
    Inventors: Vincent Ronfard, Alan Tuck, Leon Wilkins
  • Publication number: 20060240555
    Abstract: The present invention relates to fibrin cell supports for cell cultures formed by the mixture of plasma proteins including fibrinogen and thrombin. The fibrin cell supports are preferably used for preparing a culture of cells such as keratinocytes, recovering the culture in the form of a reconstituted tissue, and transporting same. The reconstituted tissue is particularly suitable for use as a skin graft.
    Type: Application
    Filed: February 24, 2006
    Publication date: October 26, 2006
    Applicant: DFB Pharmaceuticals, Inc.
    Inventor: Vincent Ronfard
  • Publication number: 20060134093
    Abstract: The present invention relates to fibrin cell supports for cell cultures formed by the mixture of plasma proteins including fibrinogen and thrombin. The fibrin cell supports are preferably used for preparing a culture of cells such as keratinocytes, recovering the culture in the form of a reconstituted tissue, and transporting same. The reconstituted tissue is particularly suitable for use as a skin graft.
    Type: Application
    Filed: September 5, 2003
    Publication date: June 22, 2006
    Applicant: DFB Pharmaceuticals, Inc.
    Inventor: Vincent Ronfard
  • Publication number: 20040126881
    Abstract: The present invention relates to fibrin cell supports for cell cultures formed by the mixture of plasma proteins including fibrinogen and thrombin. The fibrin cell supports are preferably used for preparing a culture of cells such as keratinocytes, recovering the culture in the form of a reconstituted tissue, and transporting same. The reconstituted tissue is particularly suitable for use as a skin graft.
    Type: Application
    Filed: September 4, 2003
    Publication date: July 1, 2004
    Inventor: Vincent Ronfard
  • Patent number: 6673603
    Abstract: The present invention provides the use and composition of matter of angiogenic or other growth factors expressed by combining various types and stages of differentiation of allogeneic human cell strains or lines in unencapsulated pastes (mixed with or applied to extracellular matrix material or synthetic biocompatible substances) to be temporarily applied to wounds or defects in the skin or other tissues for the restoration of blood supplying connective tissue to enable organ-specific cells to reestablish organ integrity as well as to inhibit excessive scar formation.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: January 6, 2004
    Assignee: Modex Therapeutiques, S.A.
    Inventors: E. Edward Baetge, Thomas Hunziker, Alain Limat, Vincent Ronfard
  • Publication number: 20020172705
    Abstract: Cultured tissue constructs comprising cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues their cells are derived and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention are prepared in defined media, that is, without the addition of chemically undefined components.
    Type: Application
    Filed: March 13, 2000
    Publication date: November 21, 2002
    Inventors: Michael P. Murphy, Vincent Ronfard