Patents by Inventor Vincent Sauzeau

Vincent Sauzeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of RAC1 and uses thereof for treating cancers
    Patent number: 11795144
    Abstract: The present invention concerns a compound having the following formula (I): wherein: A is in particular —N(R?a)—C(?O)—R, R?a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): X is in particular chosen from the group consisting of: —SO2—N(R?b)—, R?b being H or a (C1-C6)alkyl group, —N(R?b)—SO2—, R?b being H or a (C1-C6)alkyl group, —CO—NH—, and —NH—CO—, for use for the treatment of cancers, such as metastatic cancers.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: October 24, 2023
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, CHU NANTES
    Inventors: Vincent Sauzeau, Gervaise Loirand, Jacques Lebreton, Arnaud Tessier, Agnès Quemener
  • Inhibitors of RAC1 and uses thereof for inducing bronchodilatation
    Patent number: 11607419
    Abstract: The present invention concerns a compound having the following formula (I): wherein: —A is in particular —N(R?a)—C(?O)—R, R?a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): —X is in particular chosen from the group consisting of: —SO2—N(R?b)—, R?b being H or a (C1-C6)alkyl group, —N(R?b)—SO2—, R?b being H or a (C1-C6)alkyl group, —CO—NH—, and —NH—CO—, for use for the treatment of pathologies characterized by bronchoconstriction, such as asthma.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: March 21, 2023
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, CHU NANTES
    Inventors: Vincent Sauzeau, Gervaise Loirand, Jacques Lebreton, Arnaud Tessier, Agnes Quemenier
  • INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION
    Publication number: 20210077508
    Abstract: The present invention concerns a compound having the following formula (I): wherein: —A is in particular —N(R?a)—C(?O)—R, R?a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): —X is in particular chosen from the group consisting of: —SO2—N(R?b)—, R?b being H or a (C1-C6)alkyl group, —N(R?b)—SO2—, R?b being H or a (C1-C6)alkyl group, —CO—NH—, and —NH—CO—, for use for the treatment of pathologies characterized by bronchoconstriction, such as asthma.
    Type: Application
    Filed: June 6, 2018
    Publication date: March 18, 2021
    Inventors: Vincent SAUZEAU, Gervaise LOIRAND, Jacques LEBRETON, Arnaud TESSIER, Agnes QUEMENIER
  • INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS
    Publication number: 20200095199
    Abstract: The present invention concerns a compound having the following formula (I): wherein: A is in particular —N(R?a)—C(?O)—R, R?a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): X is in particular chosen from the group consisting of: —SO2—N(R?b)—, R?b being H or a (C1-C6)alkyl group, —N(R?b)—SO2—, R?b being H or a (C1-C6)alkyl group, —CO—NH—, and —NH—CO—, for use for the treatment of cancers, such as metastatic cancers.
    Type: Application
    Filed: June 6, 2018
    Publication date: March 26, 2020
    Inventors: Vincent SAUZEAU, Gervaise LOIRAND, Jacques LEBRETON, Arnaud TESSIER, Agnès QUEMENER
  • RAC1 inhibitors for inducing bronchodilation
    Patent number: 10155001
    Abstract: The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method for inducing bronchodilation in a patient in need thereof. The invention also relates to a Rac1 inhibitor for use in a method for reducing AHR in a patient in need thereof.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: December 18, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Centre National de la Recherche Scientifique (CNRS), Universite de Nantes, Centre Hospitalier Universitaire de Nantes
    Inventors: Vincent Sauzeau, Gwennan Andre, Gervaise Loirand, Antoine Magnan, David Lair
  • RAC1 Inhibitors for Inducing Bronchodilation
    Publication number: 20160120872
    Abstract: The invention relates to a Rac1 inhibitor for use as bronchodilator in a patient in need thereof. The invention provides a Rac1 inhibitor for use in a method for inducing bronchodilation in a patient in need thereof. The invention also relates to a Rac1 inhibitor for use in a method for reducing AHR in a patient in need thereof.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 5, 2016
    Inventors: Vincent Sauzeau, Gwennan Andre, Gervaise Loirand, Antoine Magnan, David Lair