Patents by Inventor Vincent Serra

Vincent Serra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC PRODUCT COMPRISING AN IgE FRAGMENT FOR TREATING IgE-MEDIATED INFLAMMATORY DISORDERS
    Publication number: 20230364232
    Abstract: An immunogenic product including at least one immunoglobulin or fragment thereof conjugated with a carrier protein, wherein the at least one immunoglobulin is IgE and preferably wherein the IgE fragment includes the IgE C?3 domain, and wherein the carrier protein is preferably CRM197. Also the use of this immunogenic product for treating inflammatory disorders, and in particular allergic disorders.
    Type: Application
    Filed: September 17, 2021
    Publication date: November 16, 2023
    Applicants: NEOVACS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), INSTITUT PASTEUR
    Inventors: Laurent REBER, Pierre BRUHNS, Eva CONDE GARCIA, Marija BACKOVIC, Vincent SERRA, Géraldine GROUARD-VOGEL, Romain BERTRAND
  • IMMUNOGENIC PRODUCT COMPRISING IL-4 AND/OR IL-13 FOR TREATING DISORDERS ASSOCIATED WITH ABERRANT IL-4 AND/OR IL 13 EXPRESSION OR ACTIVITY
    Publication number: 20210205427
    Abstract: An immunogenic product including a cytokine conjugated with a carrier protein, wherein the cytokine is selected from the group including IL-4, IL-13 and mixtures thereof, and wherein the carrier protein is CRM197. Further, a method for manufacturing the immunogenic product. Also, the therapeutic use of the immunogenic product for treating an inflammatory disorder associated with aberrant IL-4 and/or IL-13 expression or activity.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 8, 2021
    Applicants: NEOVACS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), INSTITUT PASTEUR
    Inventors: Géraldine GROUARD-VOGEL, Eva CONDE GARCÌA, Romain BERTRAND, Noémie CAILLOT, Laurent REBER, Pierre BRUHNS, Vincent SERRA
  • Method of preparation of alpha galactosyl ceramides compounds
    Patent number: 10870671
    Abstract: The present invention relates to a method of preparation of ?-galactosyl ceramides compounds of formula (I): comprising a step a) of glycosylation of a compound of formula (II): with a compound of formula (III):
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: December 22, 2020
    Assignee: ABIVAX
    Inventor: Vincent Serra
  • Vaccine composition for use against influenza
    Patent number: 9220767
    Abstract: The present invention relates to a vaccine composition comprising: —at least one prophylactically active agent against influenza, and —at least one adjuvant, said adjuvant being a derivative of a galactosylceramide, for use in the treatment of influenza.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: December 29, 2015
    Assignee: ABIVAX
    Inventor: Vincent Serra
  • METHOD OF PREPARATION OF ALPHA GALACTOSYL CERAMIDES COMPOUNDS
    Publication number: 20150291646
    Abstract: The present invention relates to a method of preparation of ?-galactosyl ceramides compounds of formula (I): comprising a step a) of glycosylation of a compound of formula (II): with a compound of formula (III):
    Type: Application
    Filed: October 30, 2013
    Publication date: October 15, 2015
    Applicant: ABIVAX
    Inventor: Vincent Serra
  • Methods of enhancing adjuvaticity of vaccine compositions
    Patent number: 8916164
    Abstract: The immunogenicity of vaccines is enhanced by co-administering a synthetic glycolipid, designated PBS-57, with the vaccine. PBS-57 has the ability to stimulate both a cell-mediated and humoral immune response. Co-administration of PBS-57 with a vaccine may be used in methods to stimulate one or more of a humoral immune response, a CD4+ T cell response, and a CD8+ cytotoxic T cell response.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: December 23, 2014
    Assignee: ABIVAX
    Inventor: Vincent Serra
  • Increase of immune response and targeting by antigens and/or drug linkage
    Patent number: 8642565
    Abstract: The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolipids and antigen. The said compounds are also able to target drug to CD1d restricted cells.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: February 4, 2014
    Assignee: Wittycell
    Inventor: Vincent Serra
  • Compositions for and methods of enhancing the immune response to antigens
    Patent number: 8211861
    Abstract: Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+ T cell response, a CD8+ T cell response or result in activation of antigen presenting cells. Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: July 3, 2012
    Assignee: Wittycell
    Inventor: Vincent Serra
  • Compositions for and methods of enhancing the immune response to antigens
    Patent number: 8207135
    Abstract: Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+ T cell response, a CD8+ T cell response or result in activation of antigen presenting cells. Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: June 26, 2012
    Assignee: Wittycell
    Inventor: Vincent Serra
  • VACCINE COMPOSITION FOR USE AGAINST INFLUENZA
    Publication number: 20110229519
    Abstract: The present invention relates to a vaccine composition comprising: —at least one prophylactically active agent against influenza, and —at least one adjuvant, said adjuvant being a derivative of a galactosylceramide, for use in the treatment of influenza.
    Type: Application
    Filed: October 5, 2009
    Publication date: September 22, 2011
    Inventor: Vincent Serra
  • INCREASE OF IMMUNE RESPONSE AND TARGETING BY ANTIGENS AND/OR DRUG LINKAGE
    Publication number: 20100330111
    Abstract: The present invention relates to compounds consisting of glycolipids covalently bound to an antigen or a drug via a linker. The said compounds are able to induce a stronger immune response than a composition comprising separated glycolipids and antigen. The said compounds are also able to target drug to CD1d restricted cells.
    Type: Application
    Filed: November 7, 2008
    Publication date: December 30, 2010
    Inventor: Vincent Serra
  • COMPOSITIONS FOR AND METHODS OF ENHANCING THE IMMUNE RESPONSE TO ANTIGENS
    Publication number: 20100322952
    Abstract: Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+T cell response, a CD8+T cell response or result in activation of antigen presenting cells. Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.
    Type: Application
    Filed: December 5, 2008
    Publication date: December 23, 2010
    Applicant: Wittycell
    Inventor: Vincent Serra
  • METHODS OF ENHANCING ADJUVATICITY OF VACCINE COMPOSITIONS
    Publication number: 20100285042
    Abstract: The immunogenicity of vaccines is enhanced by co-administering a synthetic glycolipid, designated PBS-57, with the vaccine. PBS-57 has the ability to stimulate both a cell-mediated and humoral immune response. Co-administration of PBS-57 with a vaccine may be used in methods to stimulate one or more of a humoral immune response, a CD4+ T cell response, and a CD8+ cytotoxic T cell response.
    Type: Application
    Filed: August 28, 2008
    Publication date: November 11, 2010
    Applicant: Wittycell
    Inventor: Vincent Serra
  • Compositions for and methods of enhancing the immune response to antigens
    Publication number: 20090162385
    Abstract: Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+ T cell response, a CD8+ T cell response or result in activation of antigen presenting cells. Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.
    Type: Application
    Filed: December 5, 2008
    Publication date: June 25, 2009
    Inventor: Vincent Serra