Abstract: The present disclosure generally provides compounds that antagonize certain T2R taste receptors, including related uses, methods, and compositions for the reduction of bitter taste and/or the enhancement of sweet taste. In certain aspects, the disclosure provides flavored articles or flavored compositions comprising such compounds, as well as uses of such compounds to reduce the bitter taste and/or enhance the sweet taste of such flavored articles or flavored compositions.

Abstract: An example medical device includes a container and tube set arranged and configured to couple to an endoscope, a first gas supply, and a second gas supply for use in an endoscopic procedure. The container and tube set includes a container having an interior volume configured to contain a fluid, a gas supply tube having a first end and a second end in fluid communication with the interior volume of the container, and a coupling mechanism having a first end and a second end, wherein the first end of the coupling mechanism is configured to engage with the second end of the gas supply tube and the second end of the coupling mechanism is configured to engage with both the first gas supply and the second gas supply interchangeably.

Abstract: A method of implementing administrative services for a compensation platform is disclosed. One or more interactive compensation representation views are generated based on an evaluation of mapping rules against a flexible ontology and current data state, the flexible ontology comprising customizable compensation components, relationships, and properties. One or more compensation representation views are dynamically updated in real-time in response to changes in compensation data, user context, or access permissions without requiring manual regeneration of the one or more compensation representations. The one or more interactive compensation representation views include a user interface element displayed in response to a user selection of compensation data, wherein the user interface element provides direct access to compensation information relevant to the selected compensation data without requiring a change to another screen or another user context.

Abstract: A method of generating customizable goal representation is disclosed. A request from a user to view a goal representation is received. A flexible goal ontology is accessed that comprises one or more goal entities, one or more goal relationships between the goal entities, or one or more goal properties, the one or more goal properties including one or more metadata attributes relating to the one or more goal entities. A set of mapping rules is obtained that defines mappings between one or more goals. The set of mapping rules is evaluated to assemble a customized goal representation tailored to the user. The customized goal representation is updated based on a revaluation of the mapping rules affected by changes to the one or more goal entities, the one or more goal relationships, or the one or more properties.

Abstract: Devices, systems, and methods for mitigating leakage from connectors and tubing of an endoscope system when the connectors and or tubing are disconnected from fluid ports of the endoscope system. A tubing assembly for connecting a fluid line to an endoscope and a fluid source may include an elongate tube having a lumen, a connector coupled to an end of the elongate tube and having a port in fluid communication with the lumen, and a fluid control component configured to selective adjust fluid flow through the lumen and the port. The fluid control component may be located in one or more of a cover for the fluid source, the tubing, the connector, and/or other components in fluid communication with the lumen. The fluid control component may be a valve. The valve may be manually actuated from a closed position to an opened position.

Abstract: Devices, systems, and methods for connecting tubes to an endoscope. A connector for connecting tubing, such as gas/lens wash tubing, to fluid ports of an endoscope may include a first end that couples with the tubing and a second end for engaging fluid ports of an endoscope. The connector may have a stabilizing component configured to facilitate securing the second end to the endoscope. In some cases, the connector may include a device coupling member configured to couple to the endoscope and a core structure adding stability to the device coupling member and configured to couple to the tubing. In some cases, the stabilizing component may include an actuator and a retention component that adjusts in response to actuation of the actuator.

Abstract: Methods and systems for coupling a tube set to an endoscope. An illustrative adaptor for coupling a tube set to an endoscope may include a planar head portion having at least one aperture, at least one floating cylinder extending from a proximal end at least partially disposed within the at least one aperture of the planar head portion to a distal tip and having a first lumen extending therethrough, at least one O-ring positioned at the distal tip of the at least one floating cylinder, and at least one biasing element disposed about an outer surface of the at least one floating cylinder and extending from a first end adjacent the at least one aperture of the planar head portion to a second end proximal to the distal tip of the at least one floating cylinder.

Abstract: Methods and systems for refilling a container during an endoscopic procedure. An illustrative container may comprise a container configured to contain a fluid, a water supply tube including a first end, a second end, and a first lumen extending therethrough and in fluid communication with the bottom portion of the container, a gas supply tube including a first end, a second end, and a second lumen extending therethrough and in operative fluid communication with container, a manifold configured to couple the water supply tube and the gas supply tube to the container and including a first end positioned interior to the container and a second end positioned exterior to the container, and a port positioned adjacent to the top portion of the container. The port may be configured to be in selective fluid communication with an interior of the container.

Abstract: Methods and systems for refilling a container during an endoscopic procedure. An illustrative container may comprise a container configured to contain a fluid within a first receptacle thereof, the container movable between a collapsed storage configuration and an expanded use configuration, a lens water supply tube including a first lumen extending therethrough, the first lumen is in fluid communication with the first receptacle of the container, a gas supply tube including a second lumen extending therethrough, the second lumen is in operative fluid communication with the first receptacle, and a port positioned adjacent to the top portion of the container. The port may be configured to be in selective fluid communication with the first receptacle of the container.

Abstract: Medical devices and methods for using medical devices are disclosed. Example fluid reservoirs and tube sets arranged and configured to couple to an endoscope for use in an endoscopic procedure are disclosed. An example fluid reservoir and tube set includes a fluid reservoir configured to contain a fluid, a fluid supply tube configured to be coupled to the endoscope and having a lumen extending therethrough, wherein the lumen is in fluid communication with the fluid reservoir and a first backflow prevention mechanism coupled to the fluid supply tube, the first backflow prevention mechanism configured to permit fluid to flow through the fluid supply line from the fluid reservoir to the endoscope and to prevent fluid from flowing back through the fluid supply tube from the endoscope to the fluid reservoir.

Abstract: In some embodiments, the present disclosure pertains to a unit dose pack for forming a bath for cleaning medical instruments. The unit dose pack may comprise at least a first chamber that contains an enzymatic detergent composition comprising one or more enzymes, the first chamber being formed from at least one first sheet of material that comprises a water-soluble film, and the at least one first sheet of material encapsulating the enzymatic detergent composition, wherein upon immersion in water, the enzymatic detergent composition is released from the first chamber into the water. In other embodiments, the present disclosure pertains to a method of cleaning a medical instrument using at least one such unit dose pack. In some embodiments, the medical instrument is an endoscope.

Abstract: Example embodiments provide a device that includes a support plate having a flat base portion and an elongated portion which extends perpendicular to the flat base portion, and a housing embodying one or more of a microphone and a speaker, and a housing backside having a set of screw holes configured to receive a set of screws to secure the support plate flat base portion to be flush mounted against the housing.

Abstract: A firearm holster includes a plate that is folded to form a cavity. The cavity is defined by a first sidewall, a trigger sidewall adjacent to the first sidewall, a second sidewall adjacent to the trigger sidewall, a barrel sidewall adjacent to both the first and second sidewalls, and a muzzle end wall. The muzzle end wall is adjacent to the first sidewall, the trigger sidewall, the second sidewall and the barrel sidewall. The firearm holster also includes a support wrap that at least partially surrounds the cavity and is fused to one or more of the first sidewall, the barrel sidewall, and the second sidewall.

Abstract: A receiver for a firearm and a method of disposing the receiver to prevent automatic reloading and/or trigger reset of a firearm are disclosed. A blocking mechanism is moveable between an upward and a downward position and the blocking mechanism is in the downward position when the firearm is in battery. The blocking mechanism automatically moves to the upward position after a round is fired and the blocking mechanism prevents automatic reloading and/or trigger reset of the firearm when in the upward position.

Abstract: Example embodiments provide a device that includes a housing backplate affixed to a housing which embodies one or more of a speaker and a microphone, a threaded channel affixed to the housing and extending perpendicular from the housing backplate, and a wall mount fitting with one or more securing tabs to hold the wall mount fitting to a wall mount plate.

Abstract: A receiver for a firearm and a method of disposing the receiver to prevent automatic reloading and/or trigger reset of a firearm are disclosed. A blocking mechanism is moveable between an upward and a downward position and the blocking mechanism is in the downward position when the firearm is in battery. The blocking mechanism automatically moves to the upward position after a round is fired and the blocking mechanism prevents automatic reloading and/or trigger reset of the firearm when in the upward position.

Abstract: An LED downlighting apparatus includes a housing with a sidewall having a front facing edge and a back facing edge positioned adjacent to a ceiling when the LED downlighting apparatus is installed in an opening of the ceiling. A depth of the sidewall is less than one inch and a thickness of at least a portion of the sidewall is less than three millimeters. An LED board and a lens are coupled to the housing. The lens is disposed with respect to the LED board such that the lens is illuminated from a back side. One or more mechanical couplers snap fit the apparatus to a junction box installed and positioned above the ceiling such that when the apparatus is snap fit to the junction box through the opening of the ceiling, the housing appears to be surface mounted to the ceiling.

Abstract: A medical device including a handle and a flexible member controlled by the handle, the handle including one or more knobs, each of the one or more knobs having a plurality of protrusions spaced circumferentially from one another, wherein the medical device comprises one or more grip-enhancing features configured to be removably coupled to the one or more knobs.

Abstract: A battery terminal connector includes a body portion with a first yoke and a second yoke extending forwardly of the body portion to form a terminal receiver hole. A power fastener extends from a rearward end of the body portion to receive one or more of an adapter, a primary cable adapter, and/or an auxiliary cable adapter. Each of the adapter, the primary cable adapter, and/or the auxiliary cable adapter extends rearwardly of the body portion. The adapter has at least a first aperture configured to be coupled to the power fastener and a second aperture configured to be coupled to the auxiliary cable adapter. The auxiliary cable adapter may be coupled to the second aperture with an auxiliary fastener. A cover is coupled over the battery terminal connector.

Abstract: Example embodiments provide a device that includes a support plate having a flat base portion and an elongated portion which extends perpendicular to the flat base portion, and a housing embodying one or more of a microphone and a speaker, and a housing backside having a set of screw holes configured to receive a set of screws to secure the support plate flat base portion to be flush mounted against the housing.