Patents by Inventor Vincenzo Bronte

Vincenzo Bronte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle conjugates and uses thereof
    Patent number: 11364305
    Abstract: Described herein are nanoparticle-based compositions, kits and methods and platforms for delivering one or more nucleic acids to a cell.
    Type: Grant
    Filed: February 17, 2020
    Date of Patent: June 21, 2022
    Assignee: UNIVERSITY OF MIAMI
    Inventors: Paolo Serafini, Jennifer Vella, Vincenzo Bronte, Pirouz Daftarian, Angel Kaifer, Serena Zilio
  • RNA Aptamers and Uses Thereof
    Publication number: 20220175935
    Abstract: Described herein and RNA aptamers that specifically bind to tumor-infiltrating myeloid cells and uses thereof.
    Type: Application
    Filed: March 3, 2020
    Publication date: June 9, 2022
    Inventors: Paolo Serafini, Silvio Bicciato, Jimmy Caroli, Adriana De La Fuente, Dimitri Van Simaeys, Serena Zilio, Vincenzo Bronte
  • Engineered Cells for Inducing Tolerance
    Publication number: 20210283177
    Abstract: The present invention relates to cells which are engineered so as to increase the cellular level of cellular FLICE [Fas-associated death domain (FADD)-like IL-1?-converting enzyme]—inhibitory protein (CFLAR). The engineered cells have the ability to induce tolerance. Enhanced tolerogenicity is useful for prolonging survival of a foreign transplant and for treatment of autoimmune diseases.
    Type: Application
    Filed: September 17, 2018
    Publication date: September 16, 2021
    Inventors: Ugur Sahin, Vincenzo Bronte, Stefano Ugel, Alessandra Fiore
  • NANOPARTICLE CONJUGATES AND USES THEREOF
    Publication number: 20200237928
    Abstract: Described herein are nanoparticle-based compositions, kits and methods and platforms for delivering one or more nucleic acids to a cell.
    Type: Application
    Filed: February 17, 2020
    Publication date: July 30, 2020
    Inventors: Paolo Serafini, Jennifer Vella, Vincenzo Bronte, Pirouz Daftarian, Angel Kaifer, Serena Zilio
  • Nanoparticle conjugates and uses thereof
    Patent number: 10561741
    Abstract: Described herein are nanoparticle-based compositions, kits and methods and platforms for delivering one or more nucleic acids to a myeloid cell.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: February 18, 2020
    Assignee: UNIVERSITY OF MIAMI
    Inventors: Paolo Serafini, Jennifer Vella, Vincenzo Bronte, Pirouz Daftarian, Angel Kaifer, Serena Zilio
  • PDE INHIBITORS IN IMMUNOTHERAPY
    Publication number: 20170224691
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing immunological-mediated disease in a subject.
    Type: Application
    Filed: September 19, 2016
    Publication date: August 10, 2017
    Inventors: Ivan M. Borrello, Paolo Serafini, Kimberly A. Noonan, Vincenzo Bronte
  • PDE5 inhibitor compositions and methods for immunotherapy
    Patent number: 9468643
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing immunological-mediated disease in a subject.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: October 18, 2016
    Assignee: The Johns Hopkins University
    Inventors: Ivan M. Borrello, Paolo Serafini, Kimberly A. Noonan, Vincenzo Bronte
  • PDE5 INHIBITOR COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
    Publication number: 20140255433
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing immunological-mediated disease in a subject.
    Type: Application
    Filed: May 19, 2014
    Publication date: September 11, 2014
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Ivan M. Borrello, Paolo Serafini, Kimberly A. Noonan, Vincenzo Bronte
  • MYELOID-DERIVED SUPPRESSOR CELLS GENERATED IN VITRO
    Publication number: 20120225038
    Abstract: A population of myeloid-derived suppressor cells and the culture procedure to obtain these in vitro starting with bone marrow cells of mice, other animals and human beings, in the presence of specific cytokine combinations used to determine concentrations, is provided.
    Type: Application
    Filed: January 28, 2009
    Publication date: September 6, 2012
    Applicant: Istituto Oncologico Veneto
    Inventors: Vincenzo Bronte, Susanna Mandruzzato
  • USE OF MYELOID CELL BIOMARKERS FOR THE DIAGNOSIS OF CANCER
    Publication number: 20120070461
    Abstract: The present invention relates to the use of myeloid cell biomarkers for the differential diagnosis, prognosis, and monitoring of renal cell carcinoma (RCC) or colorectal cancer (CRC). The present invention furthermore relates to monitoring the effect of a treatment against renal cell carcinoma (RCC) or colorectal cancer (CRC), and establishing a prognosis of the outcome of the treatment of renal cell carcinoma (RCC) or colorectal cancer (CRC). The present invention furthermore relates to panels of cellular biomarkers for use in the above methods, in particular multicolor panels for measuring said biomarkers.
    Type: Application
    Filed: September 21, 2011
    Publication date: March 22, 2012
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Harpreet SINGH, Regina MENDRZYK, Steffen WALTER, Vincenzo BRONTE, Susanna MANDRUZZATO
  • Pde5 inhibitor compositions and methods for immunotherapy
    Publication number: 20090074796
    Abstract: The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing immunological-mediated disease in a subject.
    Type: Application
    Filed: January 9, 2006
    Publication date: March 19, 2009
    Applicant: The John Hopkins University
    Inventors: Ivan M. Borrello, Paolo Serafini, Kimberly A. Noonan, Vincenzo Bronte