Patents by Inventor Vincenzo De Sio

Vincenzo De Sio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Industrial process and system for the inactivation of liquid waste
    Patent number: 11591243
    Abstract: The present invention refers to an industrial process and system that is efficient and advantageous for inactivation of liquid wastes contaminated by mutagenic, genotoxic and/or teratogenic substances arising from high potency APIs production using inactivation chemical agents and excluding ozone, heat or UV light source.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: February 28, 2023
    Assignee: CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA.
    Inventors: Ogari Pacheco, Vincenzo De Sio, Marcelo Secatto, Wellington Camarotto, Marcelo Da Silva
  • INDUSTRIAL PROCESS AND SYSTEM FOR THE INACTIVATION OF LIQUID WASTE
    Publication number: 20220041479
    Abstract: The present invention refers to an industrial process and system that is efficient and advantageous for inactivation of liquid wastes contaminated by mutagenic, genotoxic and/or teratogenic substances arising from high potency APIs production using inactivation chemical agents and excluding ozone, heat or UV light source.
    Type: Application
    Filed: May 22, 2019
    Publication date: February 10, 2022
    Inventors: Ogari PACHECO, Vincenzo DE SIO, Marcelo SECATTO, Wellington CAMAROTTO, Marcelo DA SILVA
  • Process for preparing temozolomide and an intermediary
    Patent number: 10865209
    Abstract: The present invention relates to an efficient and industrially advantageous process for preparing temozolomide and the carbamoyl-AICA intermediate through the use of N-methyl carbamoylimidazole in a good overall yield and high purity.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: December 15, 2020
    Assignee: CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA
    Inventors: Ogari Pacheco, Vincenzo De Sio, Murilo Massoni, Leandro Camargo
  • PROCESS FOR PREPARING TEMOZOLOMIDE AND AN INTERMEDIARY
    Publication number: 20200190088
    Abstract: The present invention relates to an efficient and industrially advantageous process for preparing temozolomide and the carbamoyl-AICA intermediate through the use of N-methyl carbamoylimidazole in a good overall yield and high purity.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 18, 2020
    Inventors: Ogari PACHECO, Vincenzo DE SIO, Murilo MASSONI, Leandro CAMARGO
  • Bortezomib esters and formulations thereof
    Patent number: 9206229
    Abstract: Bortezomib esters with tartaric acid wherein the molar ratio between bortezomib and tartaric acid is 2:1 and formulations containing them are described.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: December 8, 2015
    Assignee: CHEMI S.P.A.
    Inventors: Stefano Turchetta, Maurizio Zenoni, Umberto Ciambecchini, Paolo Brandi, Vincenzo De Sio, Giorgio Berardi
  • Bortezomib Esters And Formulations Thereof
    Publication number: 20150232508
    Abstract: Bortezomib esters with tartaric acid wherein the molar ratio between bortezomib and tartaric acid is 2:1 and formulations containing them are described.
    Type: Application
    Filed: August 1, 2013
    Publication date: August 20, 2015
    Inventors: Stefano Turchetta, Maurizio Zenoni, Umberto Ciambecchini, Paolo Brandi, Vincenzo De Sio, Giorgio Berardi
  • Prodrug of an anti-inflammatory active ingredient
    Patent number: 9096491
    Abstract: A process for the preparation of a prodrug of 5-aminosalicylic acid, namely 2-butanoyloxy-5-amino-benzoic acid, and solid forms of such compound are described.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: August 4, 2015
    Assignee: CHEMI S.P.A.
    Inventors: Maurizio Zenoni, Umberto Ciambecchini, Lorenzo De Ferra, Stefano Turchetta, Vincenzo De Sio
  • PRODRUG OF AN ANTI-INFLAMMATORY ACTIVE INGREDIENT
    Publication number: 20140163251
    Abstract: A process for the preparation of a prodrug of 5-aminosalicylic acid, namely 2-butanoyloxy-5-amino-benzoic acid,and solid forms of such compound are described.
    Type: Application
    Filed: July 9, 2012
    Publication date: June 12, 2014
    Applicant: CHEMI S.P.A.
    Inventors: Maurizio Zenoni, Umberto Ciambecchini, Lorenzo De Ferra, Stefano Turchetta, Vincenzo De Sio