Patents by Inventor Vinciane MARCHAND

Vinciane MARCHAND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DIAGNOSING HEMATOLOGICAL MALIGNANCIES AND ASSOCIATED KIT
    Publication number: 20240417809
    Abstract: A method for diagnosing a cancer in a subject, notably with the aim of finding fusion transcripts, includes an RT-MLPA step carried out on a biological sample obtained from the subject using the probes SEQ ID NO: 1 to 25, 30, 31 and 113 to 120, and/or with at least the probes SEQ ID NO: 374 to 405, and/or with at least the probes SEQ ID NO: 524 to 559, each of the probes being fused, at one end at least, with a priming sequence.
    Type: Application
    Filed: June 28, 2024
    Publication date: December 19, 2024
    Inventors: Philippe RUMINY, Vinciane MARCHAND, Fabrice JARDIN
  • METHOD FOR DIAGNOSING A CANCER AND ASSOCIATED KIT
    Publication number: 20220290242
    Abstract: The invention concerns a method for diagnosing a cancer in a subject, comprising a step of RT-MLPA on a biological sample obtained from the subject, in which the RT-MLPA step is carried out using at least one pair of probes comprising at least one probe chosen among the probes with SEQ ID NO: 1 to 13, and/or the probes with SEQ ID NO: 96 to 99, and/or the probes with SEQ ID NO: 866 to 938, and/or the probes with SEQ ID NO: 940 to 1104, and/or SEQ ID NO: 211 to 1312, and/or the probes with SEQ ID NO: 96 to 99, and/or the probes with SEQ ID NO: 1105 to 1107 and/or the probe with SEQ ID NO: 939 and/or the probes with SEQ ID NO: 1108 to 1123, each of the probes being fused, at at least one end, with a priming sequence, and at least one of the probes of the pair comprising a molecular barcode sequence.
    Type: Application
    Filed: November 5, 2019
    Publication date: September 15, 2022
    Inventors: Philippe RUMINY, Vinciane MARCHAND, Ahmad ABDEL SATER, Pierre-Julien VIAILLY, Marie Delphine LANIC, Fabrice JARDIN, Marick LAE, Mathieu VIENNOT
  • CLASSIFICATION OF B-CELL NON-HODGKIN LYMPHOMAS
    Publication number: 20220165355
    Abstract: An accurate gene expression based classifier, and the associated assay, which can participate to the establishment a lymphoma diagnosis and to the evaluation of individual prognosis markers are provided. Through its use, one may distinguish subtypes of lymphomas such as ABC DLBCL, GCB DLBCL, PMBL, FL, MCL, SLL and MZL from one another.
    Type: Application
    Filed: March 27, 2020
    Publication date: May 26, 2022
    Inventors: Philippe RUMINY, Vinciane MARCHAND, Victor BOBÉE, Fabrice JARDIN
  • Methods and kits for classifying diffuse large B-cell lymphomas (DLBCLs) into GCB-DLBCLs or into ABC-DLBCLs
    Patent number: 10519508
    Abstract: The present invention relates to a method for classifying a diffuse large B-cell lymphoma (DLBCL) of a subject into a GCB-DLBCL or into a ABC-DLBCL comprising the step of determining the expression level of 10 genes in a tumor tissue sample obtained from the subject by performing a Reverse Transcriptase Multiplex Ligation dependent Probe Amplification (RT-MLPA) assay wherein the 10 genes are NEK6, IRF4, IGHM, LMO2, FOXP1, TNFRSF9, BCL6, TNFRSF13B, CCND2 and MYBL1.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: December 31, 2019
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Rouen, Centre Henri Becquerrel
    Inventors: Fabrice Jardin, Philippe Ruminy, Sylvain Mareschal, Vinciane Marchand, Cristina Bagacean
  • Methods and Kits for Classifying Diffuse Large B-Cell Lymphomas (DLBCLs) Into GCB-DLBCLs or Into ABC-DLBCLs
    Publication number: 20170016074
    Abstract: The present invention relates to a method for classifying a diffuse large B-cell lymphoma (DLBCL) of a subject into a GCB-DLBCL or into a ABC-DLBCL comprising the step of determining the expression level of 10 genes in a tumor tissue sample obtained from the subject by performing a Reverse Transcriptase Multiplex Ligation dependent Probe Amplification (RT-MLPA) assay wherein the 10 genes are NEK6, IRF4, IGHM, LMO2, FOXP1, TNFRSF9, BCL6, TNFRSF13B, CCND2 and MYBL1.
    Type: Application
    Filed: March 10, 2015
    Publication date: January 19, 2017
    Inventors: Fabrice Jardin, Philippe Ruminy, Sylvain Mareschal, Vinciane Marchand, Cristina Bagacean
  • METHOD FOR DIAGNOSING HEMATOLOGICAL MALIGNANCIES AND ASSOCIATED KIT
    Publication number: 20160319362
    Abstract: A method for diagnosing a cancer in a subject, notably with the aim of finding fusion transcripts, includes an RT-MLPA step carried out on a biological sample obtained from the subject using the probes SEQ ID NO: 1 to 25, 30, 31 and 113 to 120, and/or with at least the probes SEQ ID NO: 374 to 405, and/or with at least the probes SEQ ID NO: 524 to 559, each of the probes being fused, at one end at least, with a priming sequence.
    Type: Application
    Filed: September 11, 2014
    Publication date: November 3, 2016
    Inventors: Philippe RUMINY, Vinciane MARCHAND, Fabrice JARDIN