Abstract: Implementations for receiving an integrated digital twin including multiple digital twins, each digital twin including a computer-executable model of a real-world system used to execute a portion of a process, within the integrated digital twin, a first digital twin providing output to generate input to a second digital twin, receiving enterprise data, the enterprise data being provided from a set of real-world systems used to execute the process, executing, by the integrated digital twin module, simulations of the process using the integrated digital twin and one or more agent-based models based on the enterprise data, at least one agent-based model providing input to the first digital twin, determining simulation results from the simulations, the simulation results including a value of at least one objective function, and adjusting one or more parameters of at least one real-world system used to execute the process based on the simulation results.