Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: An approach is provided for inducing table of contents (TOC) knowledge in a model-based information retrieval (IR) system. A TOC searcher in a model-based IR system is trained by fine tuning a large language model (LLM) to learn about a plurality of TOC entries specifying structures of documents and how to select from the plurality of TOC entries to respond to a query. The most granular TOC entries for a given document are identified. The given document is marked with leaf node markers which indicate the identified TOC entries. A user query is received and analyzed. By using the leaf node markers and the LLM, a TOC entry included in the identified TOC entries is identified as specifying a portion of the given document that includes an answer to the analyzed user query.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: Methods, systems, and media for automated application validation of media applications installed on a network-connected television device are provided.

Abstract: Compositions and methods for the formulation and use of recombinant adeno-associated viruses (rAAVs) are described. In certain embodiments, the application discloses recombinant Adeno-Associated Virus (rAAV or AAV) formulations that provide for one or more of the following: maintain stable freeze-thaw and lyophilization (freeze-drying) performance, and enable longer term shelf storage at temperatures above-80° C. while maintaining critical quality attributes such as genome recovery, retention of potency, minimal aggregation and degradation, improved vector quality, retaining viral protein (VP) ratios, maximum chemical stability (minimal deamidation and oxidation) and/or improved thermodynamic stability.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: Photoactive compounds are disclosed. The disclosed compounds include a diketopyrrolopyrrole derived core with pendant or fused heterocyclic, heteroaromatic, or aromatic groups and electron acceptor moieties. Many of the disclosed compounds exhibit relatively high vapor pressures to allow for purification and deposition of the compounds through thermal evaporation processes. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: Photoactive compounds are disclosed. The disclosed compounds include a metal-complexed diketopyrrolopyrrole derived core with fused and/or pendant heterocyclic, heteroaromatic, or aromatic groups. The disclosed compounds exhibit relatively high vapor pressures to allow for purification and deposition of the compounds through thermal evaporation processes. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: Control devices for network control and privacy protection are described. For network control, processing circuitry can exchange information with at least one other device to determine which device should communicate to a peripheral device. The processing circuitry can pass a token to the at least one other device in response to detecting the at least one other device should communicate to the peripheral device, and refrain from further transmissions after passing the token. In privacy control, users can be notified before audio is played on a new or different peripheral device.

Abstract: Photoactive compounds are disclosed. The disclosed photoactive compounds include metal complexes with dipyrromethene-based ligands, which can be substituted with a variety of different side chains or groups or can include various fused ring configurations, such as including aromatic or heteroaromatic groups. The metal complexes may include two dipyrromethene-based ligands, which can be the same or different. The photoactive compounds can be used as photoactive materials in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: Photoactive compounds are disclosed. The disclosed compounds can exhibit molecular structural elements tending to increase the evaporability of the compounds, such as by including geometric core disruption by use of conformationally restricted side groups instead of freely rotatable side groups or use of indandione moieties instead of dicyanomethyleneindanone moieties. The disclosed photoactive compounds include those with an imine-bridging linking moiety, which can shift the optical properties to a more red-shifted absorbance as compared to compounds with an alkene-bridging linking moiety. The disclosed photoactive compounds can be used in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: This disclosure describes systems, methods, and devices related to enhanced network performance assessment. A device may receive network quality information from an access point (AP), embedded in an Information Elements (IE) within beacon and probe response frames. The device may analyze the received network parameters. The device may compare these network parameters against predefined thresholds for network quality. The device may assess compatibility with the AP. The device may select the AP based on the assessment and the predefined thresholds.

Abstract: Photoactive compounds are disclosed. The disclosed photoactive compounds include metal complexes with dipyrromethene-based ligands, which can be substituted with a variety of different side chains or groups or can include various fused ring configurations, such as including aromatic or heteroaromatic groups. The metal complexes may include two dipyrromethene-based ligands, which can be the same or different. The photoactive compounds can be used as photoactive materials in organic photovoltaic devices, such as visibly transparent or opaque photovoltaic devices.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: Compounds, compositions and methods are provided for the inhibition of GBP1. The subject inhibitor compounds can act by inhibiting GBP1 alone and/or GBP1: pro-survival kinase (e.g. serine/threonine-protein kinase pim-1 (PIM1)) interactions. Aspects of the subject methods include contacting a cellular sample with a GBP 1 inhibitor to inhibit the GBP 1 alone and/or GBP 1: PIM 1 interactions. Also provided are compositions and methods for treating cancer. In certain cases the cancer is resistant towards chemotherapy and radiation therapy.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.

Abstract: ?-NETA analogs are provided for the treatment of inflammatory disease.

Abstract: The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.