Patents by Inventor Violetta Cecchetti

Violetta Cecchetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-d e][1,4]benzothiazine-6-carboxylic acid hydrochloride
    Patent number: 5221741
    Abstract: Process for the preparation of 9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de] [1,4]benzothiazine-6-carboxylic acid hydrochloride (Rufloxacin) by reaction of 2,3,5-trifluoro-4-(4-methyl-1-piperazinyl)benzoyl ethyl acetate with N,N-dimethylformamide dimethylacetal, followed by reaction with 2-aminoethanethiol, intramolecular cyclization by treatment with NaH, hydrolysis with H.sub.2 O and salification with HCl.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: June 22, 1993
    Assignee: Mediolanum Farmaceutici S.p.A.
    Inventors: Violetta Cecchetti, Arnaldo Fravolini, Pier Giuseppe Pagella, Fausto Schiaffella