Patents by Inventor Violetta Iotzova

Violetta Iotzova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of the P2Y10 receptor useful in altering T lymphocyte function
    Publication number: 20060257404
    Abstract: The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.
    Type: Application
    Filed: July 20, 2006
    Publication date: November 16, 2006
    Inventors: James Burke, Violetta Iotzova
  • Antibodies of the P2Y10 receptor useful in altering T lymphocyte function
    Patent number: 7101962
    Abstract: The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: September 5, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: James R. Burke, Violetta Iotzova
  • Modulators of the P2Y10 receptor useful in altering T lymphocyte function
    Publication number: 20040247599
    Abstract: The present invention relates to modulators of P2Y10. Various modulators are disclosed, including an antibody that binds specifically to P2Y10. The present invention also relates to methods of activating resting T lymphocytes and inhibiting the proliferation of activated T lymphocytes. Methods of upregulating trascription of P2Y10 mRNA in a resting T lymphocyte, methods of inducing expression of P2Y10 on the surface of a resting T lymphocyte and methods of activating a T lymphocyte are disclosed. Also disclosed are pharmaceuticals and methods of treating an immune disease.
    Type: Application
    Filed: May 13, 2004
    Publication date: December 9, 2004
    Inventors: James R. Burke, Violetta Iotzova
  • Retinoic acid receptor antagonists as promoters of angiogenesis
    Patent number: 6713515
    Abstract: Methods and compositions for treating various disorders by administering a therapeutically effective amount of a retinoic acid receptor antagonist alone or in combination or in conjunction with other therapeutic agents to promote angiogenesis are provided. Also provided are methods for obtaining additional retinoic acid receptor antagonists for use as therapeutic agents to promote angiogenesis.
    Type: Grant
    Filed: September 13, 2001
    Date of Patent: March 30, 2004
    Assignee: Bristol Myers Squibb Company
    Inventors: Violetta Iotzova, Peter Reczek
  • Retinoic acid receptor antagonists as promoters of angiogenesis
    Publication number: 20020120006
    Abstract: Methods and compositions for treating various disorders by administering a therapeutically effective amount of a retinoic acid receptor antagonist alone or in combination or in conjunction with other therapeutic agents to promote angiogenesis are provided. Also provided are methods for obtaining additional retinoic acid receptor antagonists for use as therapeutic agents to promote angiogenesis.
    Type: Application
    Filed: September 13, 2001
    Publication date: August 29, 2002
    Inventors: Violetta Iotzova, Peter Reczek