Patents by Inventor Vipul Bhargava

Vipul Bhargava has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240254161
    Abstract: The disclosure relates to ovarian cancer neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the ovarian cancer neoantigens, and methods of making and using them.
    Type: Application
    Filed: February 21, 2024
    Publication date: August 1, 2024
    Inventors: Vipul Bhargava, Vinod Krishna, David J. Pocalyko, Pegah Safabakhsh, Manuel Alejandro Sepulveda
  • Publication number: 20240139265
    Abstract: The disclosure relates to prostate neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the prostate neoantigens, and methods of making and using them.
    Type: Application
    Filed: June 27, 2023
    Publication date: May 2, 2024
    Inventors: Kurtis E. Bachman, Vipul Bhargava, Darryl L. Davis, Vinod Krishna, Guido Leoni, David Pocalyko, Pegah Safabakhsh, Manuel Sepulveda, Derick Siegel, Marco Gottardis
  • Patent number: 11945881
    Abstract: The disclosure relates to ovarian cancer neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the ovarian cancer neoantigens, and methods of making and using them.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: April 2, 2024
    Assignee: Janssen Biotech, Inc.
    Inventors: Vipul Bhargava, Vinod Krishna, David J. Pocalyko, Pegah Safabakhsh, Manuel Alejandro Sepulveda
  • Patent number: 11793843
    Abstract: The disclosure relates to prostate neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the prostate neoantigens, and methods of making and using them.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: October 24, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Kurtis E. Bachman, Vipul Bhargava, Darryl L. Davis, Vinod Krishna, Guido Leoni, David Pocalyko, Pegah Safabakhsh, Manuel Sepulveda, Derick Siegel, Marco Gottardis
  • Publication number: 20230035403
    Abstract: Disclosed herein are methods of diagnosing and treating a subject with prostate cancer, as well as methods of monitoring the responsiveness of a subject having prostate cancer to a therapeutic agent.
    Type: Application
    Filed: July 2, 2021
    Publication date: February 2, 2023
    Inventors: Denis A. Smirnov, Yashoda Rani Rajpurohit, Vipul Bhargava, Patrick Wilkinson, Kai Fu, Manuel Alejandro Sepulveda
  • Publication number: 20230029453
    Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and methods of treating and preventing prostate cancer.
    Type: Application
    Filed: July 2, 2021
    Publication date: February 2, 2023
    Inventors: Jason Lee DeHart, Vipul Bhargava, Manuel Alejandro Sepulveda
  • Publication number: 20230024133
    Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and method of treating and preventing prostate cancer using the self-replicating RNA molecules and vaccines.
    Type: Application
    Filed: July 2, 2021
    Publication date: January 26, 2023
    Inventors: Jason Lee DeHart, Vipul Bhargava, Patrick Wilkinson, Manuel Alejandro Sepulveda
  • Publication number: 20220194999
    Abstract: Disclosed herein are polypeptide fragments and polynucleotides based on mutant capicua transcriptional repressor (CIC), catenin beta 1 (CTNNB1), v-erb-b2 erythroblastic leukemia viral oncogene homolog B (ERBB2), kirsten rat sarcoma (KRAS), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), phosphatase and tensin homolog (PTEN), splicing factor 3b subunit 1 (SF3B1), SRY-box transcription factor 17 (SOX17), tumor protein 53 (TP53), and cytomegalovirus (CMV) sequences, vectors, host cells, viruses, methods for generating CD8+ T-cells, and methods of treatment. Also disclosed herein are T-cell receptors (TCRs), polynucleotides, vectors and cells comprising the TCRs, and methods of treatment.
    Type: Application
    Filed: December 20, 2021
    Publication date: June 23, 2022
    Inventors: Vinod Krishna, Manuel Alejandro Sepulveda, Vipul Bhargava, Iqbal S. Grewal, Kurtis Bachman
  • Publication number: 20210261609
    Abstract: The disclosure relates to ovarian cancer neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the ovarian cancer neoantigens, and methods of making and using them.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 26, 2021
    Inventors: Vipul BHARGAVA, Vinod Krishna, David J. Pocalyko, Pegah Safabakhsh, Manuel Alejandro Sepulveda
  • Publication number: 20210261636
    Abstract: The disclosure relates to multiple myeloma neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the multiple myeloma neoantigens, and methods of making and using them.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 26, 2021
    Inventors: Vipul BHARGAVA, Vinod Krishna, Jaymala Patel, David J. Pocalyko, Yashoda Rani Rajpurohit, Pegah Safabakhsh, Manuel Alejandro Sepulveda
  • Publication number: 20200222478
    Abstract: The disclosure relates to prostate neoantigens, polynucleotides encoding them, vectors, host cells, recombinant virus particles, vaccines comprising the neoantigens, proteinaceous molecules binding the prostate neoantigens, and methods of making and using them.
    Type: Application
    Filed: January 9, 2020
    Publication date: July 16, 2020
    Inventors: Kurtis E. Bachman, Vipul Bhargava, Darryl L. Davis, Vinod Krishna, Guido Leoni, David Pocalyko, Pegah Safabakhsh, Manuel Sepulveda, Derick Siegel, Marco Gottardis
  • Patent number: 10380339
    Abstract: Techniques are disclosed herein for reactively identifying software products, available from an electronic marketplace, that are exhibiting anomalous behavior. Data associated with software products is accessed and analyzed to determine anomalous behavior. The data analyzed may include, but is not limited to, crash data, ratings data, marketplace data, usage data, and the like. A machine learning mechanism may be used to classify the application into a category relating to whether a potential anomaly is identified for the software product. A score may also be calculated for the software applications that indicates a severity of the anomalous behavior. The classification and/or the score may be used to determine whether to perform further analysis or testing with regard to a software product. For instance, the score may be used to determine that the software product is to be tested by a testing service.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: August 13, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Srikar Appalaraju, Amol Wanjari, Amit Arora, Vipul Bhargava, Ashish Hari Chiplunkar, Vineet Khare, Chellappan Lakshmanan
  • Patent number: 10089661
    Abstract: Techniques are disclosed herein for identifying software products, available from an electronic marketplace, to be tested. Data associated with software products is accessed and analyzed to determine what software products to test. The data analyzed may include, but is not limited to, download data, crash data, ratings data, marketplace data, usage data, and the like. A machine learning mechanism may be used to predict a popularity of a software product, classify the application into a category relating to whether a potential anomaly is identified for the software product, and determine whether to test the software product. A score may also be calculated for the software products that indicates whether or not to test the software product. The predicted popularity, the classification and/or the score may be used to determine whether to perform further analysis or testing with regard to a software product.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: October 2, 2018
    Assignee: Amazon Technologies, Inc.
    Inventors: Srikar Appalaraju, Vipul Bhargava, Amol Wanjari
  • Patent number: 9920367
    Abstract: The present invention provides methods and systems for analyzing mammalian transcriptomes, particularly, for low abundant transcripts, and with the use of high throughput technologies. Heptamer primers and sequence tags generated by the iterative randomized algorithm, as well as the sequencing-library generation system for amplifying and synthesis-based sequencing low abundant transcripts using the heptamer primers are also provided. The present invention further provides the use of the invention system and method for identifying key embryological lineage specific transcripts that anticipate differentiation of specific cell types.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: March 20, 2018
    Assignee: The Regents of the University of California
    Inventors: Vipul Bhargava, Pang Ko, Shankar Subramaniam
  • Publication number: 20140148347
    Abstract: The present invention provides methods and systems for analyzing mammalian transcriptomes, particularly, for low abundant transcripts, and with the use of high throughput technologies. Heptamer primers and sequence tags generated by the iterative randomized algorithm, as well as the sequencing-library generation system for amplifying and synthesis-based sequencing low abundant transcripts using the heptamer primers are also provided. The present invention further provides the use of the invention system and method for identifying key embryological lineage specific transcripts that anticipate differentiation of specific cell types.
    Type: Application
    Filed: December 13, 2013
    Publication date: May 29, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Vipul Bhargava, Pang Ko, Shankar Subramaniam