Patents by Inventor Viraj Pramod Mane

Viraj Pramod Mane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR DETECTING HUMAN INTERFERON-ALPHA SUBTYPES AND METHODS OF USE
    Publication number: 20160090627
    Abstract: The invention provides highly sensitive, specific and efficient quantitative real-time PCR compositions, methods and assay kits to detect at least one IFN subtype and/or IFN subtype allotypic variants. Primer/probe sets complementary to the coding sequence of an IFN subtype of interest avoid spurious detection of degraded mRNA and enhances the correlation between the IFN subtype that is measured by the assays of the invention and the protein that is actually expressed. The invention also provides methods for designing primers and methods of using the compositions and assay kits. The compositions, kits, and methods of the invention may be used, for example, to monitor vaccine efficacy, autoimmune disease, chronic infections, or tumor therapy.
    Type: Application
    Filed: August 24, 2015
    Publication date: March 31, 2016
    Inventors: Ronald Rabin, Viraj Pramod Mane
  • Compositions for detecting human interferon-alpha subtypes and methods of use
    Patent number: 9193995
    Abstract: The invention provides highly sensitive, specific and efficient quantitative real-time PCR compositions, methods and assay kits to detect at least one IFN subtype and/or IFN subtype allotypic variants. Primer/probe sets complementary to the coding sequence of an IFN subtype of interest avoid spurious detection of degraded mRNA and enhances the correlation between the IFN subtype that is measured by the assays of the invention and the protein that is actually expressed. The invention also provides methods for designing primers and methods of using the compositions and assay kits. The compositions, kits, and methods of the invention may be used, for example, to monitor vaccine efficacy, autoimmune disease, chronic infections, or tumor therapy.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: November 24, 2015
    Assignee: UNITED STATES DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Ronald Rabin, Viraj Pramod Mane
  • COMPOSITIONS FOR DETECTING HUMAN INTERFERON-ALPHA SUBTYPES AND METHODS OF USE
    Publication number: 20110311973
    Abstract: The invention provides highly sensitive, specific and efficient quantitative real-time PCR compositions, methods and assay kits to detect at least one IFN subtype and/or IFN subtype allotypic variants. Primer/probe sets complementary to the coding sequence of an IFN subtype of interest avoid spurious detection of degraded mRNA and enhances the correlation between the IFN subtype that is measured by the assays of the invention and the protein that is actually expressed. The invention also provides methods for designing primers and methods of using the compositions and assay kits. The compositions, kits, and methods of the invention may be used, for example, to monitor vaccine efficacy, autoimmune disease, chronic infections, or tumor therapy.
    Type: Application
    Filed: November 20, 2009
    Publication date: December 22, 2011
    Applicant: USA, as Represented by the Secretary, Department of Health & Human Services (The Government)
    Inventors: Ronald Rabin, Viraj Pramod Mane