Abstract: Methods and compositions for treating, inhibiting, and/or preventing diseases or disorders associated with aberrant bromodomain-containing protein 4 (BRD4) and phosphoinositide 3-kinase (PBK) activity are disclosed, the methods comprise contacting a solution, cell, tissue, or subject expressing BRD4 and PBK with a compound having Benzopyran-4-One core.

Abstract: The present invention relates to a mixed complex soap based grease composition comprising a lubricating base oil; a saponifiable material; a metal oxide; an alkali/alkaline metal hydroxide; and a complexing acid. The present invention also discloses a single-step, open kettle, energy-efficient process which gives smooth textured zinc-alkali/alkaline earth metal mixed complex grease composition with relatively low thickener content while still maintaining desired consistency. The zinc-alkali/alkaline earth metal mixed complex grease composition is tailor made to have dropping point in a range of 180° C. to 300° C. comparable to lithium and lithium complex grease composition, have inherent oxidation stability, extreme pressure, anti-wear properties, and water resistance properties. The zinc-alkali/alkaline earth metal mixed complex grease composition shows excellent additive response good mechanical stability, low temperature properties, pumpability, and corrosion resistance.

Abstract: Zinc complex greases with different complexing acids having dropping points comparable to lithium greases and tailor-made dropping points can be made by processing at low temperature in open as well as close kettle process. The present invention discloses a process of manufacturing Zinc complex greases—through reaction of fatty acid and complexing acid with zinc oxide in mineral oil to obtain zinc complex greases having high dropping points of 180 to 280° C.

Abstract: A radiator includes a radiator frame, an array of tube assemblies each including a coolant tube and a tube clip supported in the radiator frame, and a lateral bump stop fitted between the array of tube assemblies and the radiator frame. The lateral bump stop includes cushions arranged in a staggered cushion pattern complementary to a staggered packing pattern of the tube assemblies with each of the cushions in contact with the tube clip of one of the tube assemblies.

Abstract: Zinc complex greases with different complexing acids having dropping points comparable to lithium greases and tailor-made dropping points can be made by processing at low temperature in open as well as close kettle process. The present invention discloses a process of manufacturing Zinc complex greases—through reaction of fatty acid and complexing acid with zinc oxide in mineral oil to obtain zinc complex greases having high dropping points of 180 to 280° C.

Abstract: A support assembly for attaching a heat exchanger to a frame of a machine. The support assembly including a clip having one or more attachment features for attaching to the frame and a support member disposed between a first fin portion and a second fin portion of the heat exchanger. The support member disposed between the clip and the tube member to at least partially surrounds a perimeter of the tube member and form a seal therewith.

Abstract: A radiator includes a radiator frame, an array of tube assemblies each including a coolant tube and a tube clip supported in the radiator frame, and a lateral bump stop fitted between the array of tube assemblies and the radiator frame. The lateral bump stop includes cushions arranged in a staggered cushion pattern complementary to a staggered packing pattern of the tube assemblies with each of the cushions in contact with the tube clip of one of the tube assemblies.

Abstract: A support assembly for attaching a heat exchanger to a frame of a machine. The support assembly including a clip having one or more attachment features for attaching to the frame and a support member disposed between a first fin portion and a second fin portion of the heat exchanger. The support member disposed between the clip and the tube member to at least partially surrounds a perimeter of the tube member and form a seal therewith.

Abstract: Disclosed are processes for preparation of spray dried powder and utilization as an ingredient in the preparation of fried bakery products particularly doughnuts and types thereof. This doughnut base powder is spray dried with emulsifiers and stabilizers to provide improved eating and keeping qualities of the doughnuts made thereof. This base powder includes fat from animal, vegetable, or dairy origin, emulsifiers, water soluble protein solids, salt, carbohydrates and stabilizers. The above compositions can be directly added with the flour, yeast or chemical leavening agents as well as supplemented with optional flavor, color and preservative to produce either an yeast raised or a cake doughnut with or without the utilization of eggs.

Abstract: The present invention relates to a spray dried 20-65% of natural mango pulp base powder which is composed of 21-55% of fat which can be used as an alternative to mango based desserts, soft serve ice creams and fillings. A functional fat filled natural mango powder comprise of 21-55% by weight of fat, 1-5% by weight of one or more proteins, 0.5-5% by weight of one or more emulsifier system, 1.5-2.0% by weight of buffers, 1-5% by weight of water and the balance is made up of non-starchy carbohydrates, antioxidants and stabilizers. Optionally flavor, color and anticaking agents can be supplemented to the composition. The above composition can be used directly or after reconstituted with water, to prepare foods such as desserts, fillings, mango shake. A functional fat filled natural mango powder can be conveniently used to develop processed food products such as soft serve ice cream, mango whipped toppings, mango mousse, mango puddings, kheer, custard, shrikhand, mango lassi.

Abstract: A distributed service node includes a voice browser, media resources, such as automatic speech recognition (ASR) engines and text-to-speech (TTS) engines, and a resource manager. A media gateway converts between a pulse code modulation (PCM) format used in a circuit-switched telephone network and a real-time packet media format used by the distributed service node. A caller places a call to telephone number associated with the media gateway, and a real-time packet media session is established between the media gateway and the distributed service node. The voice browser queries a location server to determine the location of an interactive application associated with the called telephone number and then queries an application server corresponding to the location to obtain the interactive application as a voice extensible markup language (VXML) document. The browser interprets the VXML document and responsively invokes the media resources to provide an interactive media service to the caller.