Patents by Inventor Virender M. Labroo

Virender M. Labroo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating dermatitis and related conditions
    Patent number: 5416098
    Abstract: Methods and pharmaceutical compositions for the treatment of dermatitis are disclosed. 2,3-diaryl-1-benzopyrans and their pharmaceutically acceptable salts are formulated into medicaments, including oral and topical medicaments, which are administered to a patient suffering from dermatitis. The methods and compositions are particularly useful in the treatment of conditions characterized by hyperproliferation of keratinocytes, such as psoriasis.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: May 16, 1995
    Assignee: ZymoGenetics, Inc.
    Inventors: Virender M. Labroo, James R. Piggott
  • Methods for treatment and prevention of bone loss using 2,3-benzopyrans
    Patent number: 5389646
    Abstract: Methods and pharmaceutical compositions for reducing bone loss are disclosed. 2,3-diaryl-1-benzopyrans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. Formulations include tablets and other forms suitable for oral administration and controlled-release subdermal implants.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: February 14, 1995
    Assignee: ZymoGenetics, Inc.
    Inventor: Virender M. Labroo
  • Methods for reducing bone loss using centchroman derivatives
    Patent number: 5280040
    Abstract: Methods and pharmaceutical compositions for reducing bone loss are disclosed. 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. An exemplary 3,4-diarylchroman is centchroman (3,4-trans-2,2-dimethyl-3-phenyl-4-[p-(beta-pyrrolidinoethoxy)phenyl]-7-me thoxy-chroman). Formulations include tablets and other forms suitable for oral administration and controlled-release subdermal implants.
    Type: Grant
    Filed: March 11, 1993
    Date of Patent: January 18, 1994
    Assignee: ZymoGenetics, Inc.
    Inventors: Virender M. Labroo, James R. Piggott, Steven D. Bain
  • Thionated analogues of thyrotropin releasing hormone
    Patent number: 5244884
    Abstract: There are disclosed thionated analogues of thyrotropin releasing hormone, having the formula: ##STR1## wherein, Q, W, X and Y, same or different, are oxygen or sulfur, with the proviso that at least one of Q, W, X and Y is always sulfur;Z is lower alkyl or (4-imidazolyl)methyl; and the pharmaceutically acceptable salts thereof. The disclosed compounds highly and selectively bind to TRH binding sites in animal tissues, and their utility in treating a variety of diverse physical conditions is disclosed. Pharmaceutical compositions containing the compounds are also disclosed.
    Type: Grant
    Filed: October 19, 1992
    Date of Patent: September 14, 1993
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Arno F. Spatola, Leszek Lankiewicz, Virender M. Labroo, Stefan Vonhof