Patents by Inventor Virendra K. Sharma

Virendra K. Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for Delivering Amino Acids or Peptides with Antioxidant Activity into Mitochondria
    Publication number: 20110257107
    Abstract: Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compounds are useful for inhibiting oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.
    Type: Application
    Filed: June 27, 2011
    Publication date: October 20, 2011
    Applicant: University of Rochester
    Inventors: Shey-Shing Sheu, Marion W. Anders, Lin Xu, Virendra K. Sharma, Dhanajaya Nauduri
  • Compounds for Delivering Amino Acids or Peptides with Antioxidant Activity into Mitochondria and Use Thereof
    Publication number: 20090298782
    Abstract: Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compounds are useful for inhibiting oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.
    Type: Application
    Filed: December 18, 2006
    Publication date: December 3, 2009
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Shey-Shing Sheu, Marion W. Anders, Lin Xu, Virendra K. Sharma, Dhananjaya Nauduri
  • Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof
    Patent number: 7585846
    Abstract: Disclosed are hydrophilic choline/N-heterocycle ester compounds containing single amino acids, peptides, or derivatives thereof which have the potential to express anti-oxidant activity capable of reducing reactive oxygen species in cells. These compounds may be used to inhibit oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: September 8, 2009
    Assignee: University of Rochester
    Inventors: Shey-Shing Sheu, Marion W. Anders, Lin Xu, Virendra K. Sharma