Patents by Inventor Virginia B. Kraus

Virginia B. Kraus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detecting osteoarthritis and predicting progression thereof
    Patent number: 11560594
    Abstract: Provided herein are methods and biomarkers useful for detecting and diagnosing osteoarthritis and predicting the progression of osteoarthritis in subjects. The diagnoses and predictions of prognosis may be used to develop treatment plans for subjects. Also included are methods of treating subjects and administering pharmaceuticals based on the diagnosis and prognosis predictions.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: January 24, 2023
    Assignee: Duke University
    Inventors: Virginia B. Kraus, Jonathan B. Catterall, Erik Soderblom, Martin A. Moseley, Sunil Suchindran
  • METHODS OF DETECTING OSTEOARTHRITIS AND PREDICTING PROGRESSION THEREOF
    Publication number: 20200232034
    Abstract: Provided herein are methods and biomarkers useful for detecting and diagnosing osteoarthritis and predicting the progression of osteoarthritis in subjects. The diagnoses and predictions of prognosis may be used to develop treatment plans for subjects. Also included are methods of treating subjects and administering pharmaceuticals based on the diagnosis and prognosis predictions.
    Type: Application
    Filed: February 5, 2016
    Publication date: July 23, 2020
    Applicant: Duke University
    Inventors: Virginia B. Kraus, Jonathan B. Catterall, Erik Soderblom, Martin A. Moseley, Sunil Suchindran
  • DIRECT DRUG DELIVERY SYSTEM BASED ON THERMALLY RESPONSIVE BIOPOLYMERS
    Publication number: 20140364371
    Abstract: A method for delivering a drug depot of a compound of interest to a selected region in a subject. The method comprises administering a composition directly to said region of interest, the composition comprising the compound of interest to be delivered (such as an antiinflammatory agent or a chemotherapeutic agent) and a polymer (such as an elastin-like peptide or ELP) that undergoes an inverse temperature phase transition, so that a sustained release of the compound of interest at the selected region is provided. Compositions useful for carrying out the invention are also described.
    Type: Application
    Filed: June 5, 2014
    Publication date: December 11, 2014
    Inventors: Lori A. Setton, Ashutosh Chilkoti, Virginia B. Kraus, Helawe Betre, Matthew R. Dreher
  • DIRECT DRUG DELIVERY SYSTEM BASED ON THERMALLY RESPONSIVE BIOPOLYMERS
    Publication number: 20110236384
    Abstract: A method for delivering a drug depot of a compound of interest to a selected region in a subject. The method comprises administering a composition directly to said region of interest, the composition comprising the compound of interest to be delivered (such as an antiinflammatory agent or a chemotherapeutic agent) and a polymer (such as an elastin-like peptide or ELP) that undergoes an inverse temperature phase transition, so that a sustained release of the compound of interest at the selected region is provided. Compositions useful for carrying out the invention are also described.
    Type: Application
    Filed: January 24, 2011
    Publication date: September 29, 2011
    Applicant: Duke University
    Inventors: Lori A. SETTON, Ashutosh Chilkoti, Virginia B. Kraus, Helawe Betre, Matthew R. Dreher