Patents by Inventor Virginia Basso

Virginia Basso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use Of Naturally Occurring Cyclic Peptides For Treatment Of SARS-COV-2 Infection
    Publication number: 20240108702
    Abstract: Methods for treating and/or SARS-CoV-2 infection are described that inhibit viral replication, multiple protease activities, and provide anti-inflammatory activity. Such activities can be provided by a single species, such as a naturally occurring cyclic peptide.
    Type: Application
    Filed: January 12, 2022
    Publication date: April 4, 2024
    Inventors: Michael E. Selsted, Dat Q. Tran, Patti Tran, Justin B. Schaal, Virginia Basso, Prasad Tongaonkar
  • COMPOSITIONS AND METHODS FOR TREATMENT OF FUNGAL INFECTIONS
    Publication number: 20230072433
    Abstract: Novel peptide analogs of a ?-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These novel ?-defensin analogs are protective at concentrations where naturally occurring ?-defensins have no apparent effect, and include a core set of structural and sequence features not found in native ?-defensins.
    Type: Application
    Filed: July 20, 2022
    Publication date: March 9, 2023
    Inventors: Michael E. Selsted, Dat Q. Tran, Justin B. Schaal, Virginia Basso
  • Compositions and methods for treatment of fungal infections
    Patent number: 11427617
    Abstract: Novel peptide analogs of a ?-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These novel ?-defensin analogs are protective at concentrations where naturally occurring ?-defensins have no apparent effect, and include a core set of structural and sequence features not found in native ?-defensins.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: August 30, 2022
    Assignee: THE UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Michael E. Selsted, Dat Q. Tran, Justin B. Schaal, Virginia Basso
  • COMPOSITIONS AND METHODS FOR TREATMENT OF FUNGAL INFECTIONS
    Publication number: 20210403523
    Abstract: Peptide analogs of a ?-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These ?-defensin analogs are protective at concentrations where naturally occurring ?-defensins have no apparent effect, and include a core set of structural and sequence features not found in native ?-defensins.
    Type: Application
    Filed: June 25, 2021
    Publication date: December 30, 2021
    Inventors: Michael E. Selsted, Dat Q. Tran, Justin B. Schaal, Virginia Basso
  • COMPOSITIONS AND METHODS FOR TREATMENT OF FUNGAL INFECTIONS
    Publication number: 20200407399
    Abstract: Novel peptide analogs of a ?-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These novel ?-defensin analogs are protective at concentrations where naturally occurring ?-defensins have no apparent effect, and include a core set of structural and sequence features not found in native ?-defensins.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 31, 2020
    Inventors: Michael E. Selsted, Dat Q. Tran, Justin B. Schaal, Virginia Basso