Patents by Inventor Virginia Braman

Virginia Braman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADMINISTRATION OF DEUTERATED CFTR POTENTIATORS
    Publication number: 20200375973
    Abstract: Disclosed is a method of treating in a subject of treating diseases and conditions that are beneficially treated by administering a CFTR potentiator The method comprises administering to the subject an amount in the range of about 50 mg to about 200 mg once a day of Compound (I) or (II): or pharmaceutically acceptable salts thereof. This invention also provides compositions comprising Compound (I) or (II) and the use of such compositions in methods.
    Type: Application
    Filed: May 14, 2020
    Publication date: December 3, 2020
    Inventor: Virginia Braman
  • TREATMENT OF HAIR LOSS DISORDERS WITH DEUTERATED JAK INHIBITORS
    Publication number: 20200222408
    Abstract: Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I): or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods.
    Type: Application
    Filed: December 5, 2019
    Publication date: July 16, 2020
    Inventors: Amanda T. Wagner, James V. Cassella, Philip B. Graham, Virginia Braman, Vinita Uttamsingh, Jana Von Hehn, Colleen E. Hamilton
  • Treatment of hair loss disorders with deuterated JAK inhibitors
    Patent number: 10561659
    Abstract: Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I), or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: February 18, 2020
    Assignee: Concert Pharmaceuticals, Inc.
    Inventors: Amanda T. Wagner, James V. Cassella, Philip B. Graham, Virginia Braman, Vinita Uttamsingh, Jana Von Hehn, Colleen E. Hamilton
  • TREATMENT OF HAIR LOSS DISORDERS WITH DEUTERATED JAK INHIBITORS
    Publication number: 20190160068
    Abstract: Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I), or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 30, 2019
    Inventors: Amanda T. Wagner, James V. Cassella, Philip B. Graham, Virginia Braman, Vinita Uttamsingh, Jana Von Hehn, Colleen E. Hamilton
  • ADMINISTRATION OF DEUTERATED CFTR POTENTIATORS
    Publication number: 20180353500
    Abstract: Disclosed is a method of treating in a subject of treating diseases and conditions that are beneficially treated by administering a CFTR potentiator The method comprises administering to the subject an amount in the range of about 50 mg to about 200 mg once a day of Compound (I) or (II) or pharmaceutically acceptable salts thereof, This invention also provides compositions comprising Compound (I) or (II) and the use of such compositions in methods.
    Type: Application
    Filed: September 21, 2016
    Publication date: December 13, 2018
    Inventor: Virginia Braman
  • SUBSTITUTED XANTHINE DERIVATIVES
    Publication number: 20140296263
    Abstract: The present invention in one embodiment relates to a compound of Formula (I); or a pharmaceutically acceptable salt thereof, wherein: each of R1 and R2 is independently selected from —CH3 and —CD3; R3 is hydrogen or deuterium; each of Z1, Z2 and Z3 is independently selected from hydrogen and deuterium; each Z4 is hydrogen or deuterium; each Z5 is hydrogen or deuterium; and each Z6 is hydrogen or deuterium.
    Type: Application
    Filed: July 19, 2012
    Publication date: October 2, 2014
    Applicant: CONCERT PHARMACEUTICALS, INC.
    Inventors: Ara Aslanian, Dolly Parasrampuria, Kristine Hogan, Virginia Braman, Changfu Cheng