Patents by Inventor Virginie Fabre

Virginie Fabre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for purifying the rabies virus
    Patent number: 9750800
    Abstract: The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: September 5, 2017
    Assignee: Sanofi Pasteur SA
    Inventors: Virginie Fabre, Celine Rocca, Pierre Riffard, Eric Calvosa
  • Method for Purifying the Rabies Virus
    Publication number: 20150216963
    Abstract: The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
    Type: Application
    Filed: January 9, 2015
    Publication date: August 6, 2015
    Applicant: Sanofi Pasteur SA
    Inventors: Virginie Fabre, Celine Rocca, Pierre Riffard, Eric Calvosa
  • Stabilizing excipient for inactivated whole virus vaccine
    Patent number: 9028839
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: May 12, 2015
    Assignee: Sanofi Pasteur S.A.
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Method for purifying the rabies virus
    Patent number: 8961997
    Abstract: The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
    Type: Grant
    Filed: April 8, 2010
    Date of Patent: February 24, 2015
    Assignee: Sanofi Pasteur SA
    Inventors: Virginie Fabre, Céline Rocca, Pierre Riffard, Eric Calvosa
  • STABILIZING EXCIPIENT FOR INACTIVATED WHOLE VIRUS VACCINE
    Publication number: 20140037684
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Application
    Filed: October 8, 2013
    Publication date: February 6, 2014
    Applicant: Sanofi Pasteur
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Stabilizing excipient for inactivated whole virus vaccine
    Patent number: 8557253
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: October 15, 2013
    Assignee: Sanofi Pasteur SA
    Inventors: Alain Francon, Michel Chevalier, Nadege Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Stabilizing Excipient for Inactivated Whole Virus Vaccine
    Publication number: 20110081380
    Abstract: The invention relates to a vaccine composition comprising: a) inactivated whole virus, and b) a stabilizing excipient which comprises: i. a buffer solution, ii. a mixture of essential and nonessential amino acids, iii. a disaccharide, iv. a polyol, v. a chelating agent, vi. urea or a urea derivative, and vii. a nonionic surfactant.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 7, 2011
    Applicant: SANOFI PASTEUR
    Inventors: Alain Françon, Michel Chevalier, Nadège Moreno, Eric Calvosa, Sandrine Cigarini, Virginie Fabre
  • Method for purifying the rabies virus
    Publication number: 20100260798
    Abstract: The subject of the invention is a method for purifying the rabies virus, comprising a single ion-exchange chromatography step, said step being cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography support comprising a polymethacrylate matrix onto which sulfoisobutyl groups have been grafted such that the rabies virus binds to this support, and; b) the virus is eluted from its support.
    Type: Application
    Filed: April 8, 2010
    Publication date: October 14, 2010
    Applicant: SANOFI PASTEUR
    Inventors: Virginie Fabre, Céline Rocca, Pierre Riffard, Eric Calvosa