Patents by Inventor Virginie Poncelet

Virginie Poncelet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonyl-Derivatives as Novel Inhibitors or Histone Deacetylase
    Publication number: 20080108601
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: October 29, 2007
    Publication date: May 8, 2008
    Inventors: Kristof Van Emelen, Janine Arts, Leo-Jacobus Backx, Hans De Winter, Sven Van Brandt, Marc Verdonck, Lieven Meerpoel, Isabelle Pilatte, Virginie Poncelet, Alexey Dyatkin, Jimmy Van heusden
  • SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
    Publication number: 20070142393
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: January 30, 2007
    Publication date: June 21, 2007
    Inventors: Kristof Emelen, Janine Arts, Leo Backx, Hans De Winter, Sven Van Brandt, Marc Verdonck, Lieven Meerpoel, Isabelle Pilatte, Virginie Poncelet, Alexey Dyatkin, Jimmy Van heusden
  • Pyrido-and pyrimidopyrimidine derivatives as anti-profilerative agents
    Publication number: 20070078132
    Abstract: The present invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein a1-a2=a3-a4 represents a divalent radical selected from N—CH?CH—CH, N—CH?N—CH or CH—CH?N—CH; Z represents NH; Y represents —C3-9alkyl-, —C1-5alkyl-NR13—C1-5alkyl-, —C1-6alkyl-NH—CO— or —CO—NH—C1-6alkyl-; X1 represents —O— or —NR11—; X2 represents —C1-2alkyl-, —O—C1-2alkyl, —O— or —O—CH2—; R1 represents hydrogen or halo; R2 represents hydrogen, cyano, halo, hydroxycarbonyl-, C1-4alkyloxycarbonyl-, Het16-carbonyl- or Ar5; R3 represents hydrogen; R4 represents hydroxy, C1-4alkyloxy-, Ar4—C1-4alkyloxy or R4 represents C1-4alkyloxy substituted with one or where possible two or more substituents selected from C1-4alkyloxy- or Het2-; R11 represents hydrogen; R12 represents hydrogen, C1-4alkyl- or C1-4alkyl-oxy-carbonyl-; R13 represents Het14-C1-4alkyl, in particular morpholinyl-C1-4alkyl; Het2 represents a heterocycle select
    Type: Application
    Filed: December 15, 2004
    Publication date: April 5, 2007
    Inventors: Eddy Freyne, Marc Willems, Pierre Storck, Virginie Poncelet, Kristof Van Emelen, Peter Jacobus Johnnes Buijnsters, Werner Embrechts, Timothy Perera
  • Farnesyl transferase inhibiting 4-heterocyclyl-quinoline and quinazoline derivatives
    Publication number: 20060135769
    Abstract: This invention comprises the novel compounds of formula (I): wherein s, t, Y1, Y2, R1, R2, R3, R4, R5, R6 and R7have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: February 7, 2006
    Publication date: June 22, 2006
    Inventors: Patrick Angibaud, Marc Venet, Virginie Poncelet
  • Amino-derivatives as novel inhibitors of histone deacetylase
    Publication number: 20050119250
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: March 11, 2003
    Publication date: June 2, 2005
    Inventors: Patrick Angibaud, Kristof Van Emelen, Virginie Poncelet, Bruno Roux
  • Sulfonyl-Derivatives as novel inhibitors of histone deacetylase
    Publication number: 20050113373
    Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
    Type: Application
    Filed: March 11, 2003
    Publication date: May 26, 2005
    Inventors: Kristof Van Emelen, Janine Arts, Leo Backx, Hans De Winter, Sven Van Brandt, Marc Verdonck, Lieven Meerpoel, Isabelle Pilatte, Virginie Poncelet, Alexey Dyatkin