Patents by Inventor Virginio Castagnola

Virginio Castagnola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Orally administered pharmaceutical composition for use in gastrointestinal washes, in particular for diagnostic use, or as a cathartic laxative
    Patent number: 5124144
    Abstract: The invention provides an orally administered pharmaceutical composition for use in gastrointestinal washes, particularly for diagnostic use, or as a cathartic laxative, of the type containing polyethyleneglycol, anhydrous sodium sulphate, sodium bicarbonate, sodium chloride and potassium chloride, characterized by also containing the following components: saccharin, acesulfame-K and a flavoring chosen from the following: mandarin, fresh fruit flavoring.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: June 23, 1992
    Assignee: Giuliani S.p.A.
    Inventors: Enzo Giorgetti, Virginio Castagnola, deceased, Giuliano Frigerio
  • Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
    Patent number: 4981983
    Abstract: New derivatives of chenodeoxycholic, ursodeoxy cholic, cholic and ursocholic acids, bearing a methyl group in the side chain in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described.The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.
    Type: Grant
    Filed: October 2, 1989
    Date of Patent: January 1, 1991
    Assignee: Gipharmex S.p.A.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari, Aldo Roda
  • Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions
    Patent number: 4892868
    Abstract: New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic acids, bearing a methyl group in the side chain, in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described.The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.
    Type: Grant
    Filed: July 10, 1986
    Date of Patent: January 9, 1990
    Assignee: Gipharmex, S.p.A.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari, Aldo Roda
  • Derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
    Patent number: 4565810
    Abstract: New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic bile acids having in the side chain in the 19 position a cyclopropane ring are described together with taurine and glycine conjugated derivatives thereof.The compounds of the invention, prepared from suitable olephinic intermediates by reaction with alkyl diazoacetates or by Simmons-Smith reaction and optional conjugation with taurine or glycine, are endowed with interesting therapeutic properties.
    Type: Grant
    Filed: April 24, 1984
    Date of Patent: January 21, 1986
    Assignee: Lehner A.G.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari
  • New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
    Patent number: 4514393
    Abstract: Derivatives of biliary acids having formula I ##STR1## wherein St has the meaning of the 17-etiocholanyl residue, having two or more hydroxyl groups both in the .alpha. and .beta. conformation, some of which being optionally replaced by keto groups, and their pharmaceutically acceptable salts with alkaline or alkali-earth metals, or with organic bases.
    Type: Grant
    Filed: July 22, 1983
    Date of Patent: April 30, 1985
    Assignee: Lehner AG
    Inventors: Virginio Castagnola, Giuliano E. Frigerio, Roberto Pellicciari