Patents by Inventor Vishal Jhanji

Vishal Jhanji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250137995
    Abstract: The present disclosure relates to a method of determining effectiveness of corneal stromal stem cell therapy through evaluation of stem cell markers, inflammation markers, and assessing a scarring index.
    Type: Application
    Filed: January 6, 2025
    Publication date: May 1, 2025
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Hin-Fai YAM, Yiqin DU, Vishal JHANJI, Isabelle BILLIG, Jose Alain SAHEL, Deepinder K. DHALIWAL
  • Publication number: 20250082728
    Abstract: Described here are ophthalmic compositions and methods for treatment of dry eye disease. One ophthalmic composition includes an effective amount of interleukin-4 (IL-4) in a free uncomplexed form, or as a complex with a dermatan sulfate. A second ophthalmic composition includes an effective amount of interleukin-13 (IL-13) in a free uncomplexed form, or as a complex with a dermatan sulfate. A third ophthalmic composition includes effective amounts of IL-4 and IL-13 in a free uncomplexed form, or as a complex with a dermatan sulfate. A fourth ophthalmic composition includes at least one activator of interleukin-4 receptor signaling in a free uncomplexed form, or as a complex with a dermatan sulfate.
    Type: Application
    Filed: November 22, 2024
    Publication date: March 13, 2025
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Alexis Lauren NOLFI, Bryan Nicklaus BROWN, Mangesh KULKARNI, Vishal JHANJI
  • Publication number: 20210401941
    Abstract: Ophthalmic devices coated with an active agent eluting coating are provided herein. Placement of the coated ophthalmic devices on the surface of eye results in modulation of cells responding to an immune modifying agent and reducing inflammation-related complications in the eye. Methods for treating ocular disorders are also provided herein. The disclosed subject matter is based, in part, on the discovery that ophthalmic devices coated with a cytokine eluting coating can shift early-stage macrophage polarization associated with alleviation of symptoms and causes of inflammatory ocular disorders.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Mangesh Kulkarni, Alexis Nolfi, Bryan Nicklaus Brown, Vishal Jhanji