Patents by Inventor Vishal RAI

Vishal RAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE
    Publication number: 20220299521
    Abstract: The invention pertains to chemoselective sensitivity booster for tagging a peptide, peptide conjugate, or similar reactive molecule for analysis of a peptide, protein, antibody, protein bioconjugate, antibody bioconjugate, and similar analytes. The sensitivity booster comprises of sp2 or sp3 nitrogen centers in combination with hydrophobic carbon chains linked with an electrophile or nucleophile for attachment with a peptide, peptide conjugate, or molecules with similar reactivity.
    Type: Application
    Filed: June 4, 2020
    Publication date: September 22, 2022
    Inventors: Vishal RAI, Rohith SINGUDAS, Neelesh Chandrakant REDDY
  • METHOD FOR METAL-FREE PURIFICATION OF PROTEIN FROM A PROTEIN MIXTURE OR A CELL LYSATE WITH THE N-TERMINUS GLYCINE TAGGING
    Publication number: 20220204554
    Abstract: The invention pertains to the method of N-terminus Glycine tagged metal-free protein purification by selective labeling of N-terminus Gly containing proteins, its capture, and release through modified resin under mild operating conditions. The selective labeling of N-terminus Glycine enables the formation of an aminoalcohol. The invention is for selective tagging of N-Gly in a protein. The invention is for separation of immobilised N-terminus glycine proteins from the functionalised resin under mild aqueous physiological conditions by C—C bond dissociation with additive, in which the additive enables the resonance-assisted electron density (RED) polarization to facilitate C—C bond dissociation. The invention provides the N-Gly specific installation of a probe in a protein within cell lysate. The invention covers the special aldehydes, including its on-resin derivative, for the given purpose.
    Type: Application
    Filed: April 17, 2020
    Publication date: June 30, 2022
    Applicant: INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH BHOPAL
    Inventor: Vishal RAI
  • Multi-functional chemical agents, and the method for protein modification
    Patent number: 11149058
    Abstract: A multifunctional chemical agents comprising functional agents Fn1, Fn2 and linkers, for the linchpin directed (LDM), protein directed (PDPM) modifications of proteins, and Fn1 accelerated kinetic labeling by Fn2.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: October 19, 2021
    Assignees: Department of Biotechnology, Indian Institute of Science Education and Research Bhopal
    Inventors: Vishal Rai, Srinivasa Rao Adusumalli
  • Multi-Functional Chemical Agents, and the Method for Protein Modification
    Publication number: 20210163526
    Abstract: A multifunctional chemical agents comprising functional agents Fn1, Fn2 and linkers, for the linchpin directed (LDM), protein directed (PDPM) modifications of proteins, and Fn1 accelerated kinetic labeling by Fn2.
    Type: Application
    Filed: November 17, 2016
    Publication date: June 3, 2021
    Applicants: Department of Biotechnology, Indian Institute of Science Education and Research
    Inventors: Vishal RAI, Srinivasa Rao ADUSUMALLI
  • Multi-Functional Chemical Agents, and the Method for Protein Modification
    Publication number: 20190085020
    Abstract: A multifunctional chemical agents comprising functional agents Fn1, Fn2 and linkers, for the linchpin directed (LDM), protein directed (PDPM) modifications of proteins, and Fn1 accelerated kinetic labeling by Fn2.
    Type: Application
    Filed: November 17, 2016
    Publication date: March 21, 2019
    Applicants: Department of Biotechnology, Indian Institute of Science Education and Research
    Inventors: Vishal RAI, Srinivasa Rao ADUSUMALLI