Abstract: The present disclosure encompasses a process for chiral resolution of racemic amines, particularly ethyl 2-(4-((tert-butoxycarbonyl)amino)phenyl)piperidine-3-carboxylate, into its desired isomer, ethyl (2R,3S)-2-(4-((tert-butoxycarbonyl)amino)phenyl)-piperidine-3-carboxylate, which is an intermediate useful in the synthesis of Avacopan.

Abstract: Provided is a method and device for displaying a position of a first device on a second device. The method includes: detecting, by a device using a UWB chip, position coordinates in a first coordinate system of the first device with respect to a position of the device; converting, by the device, the position coordinates of the first device in the first coordinate system into position coordinates of the first device in a global coordinate system; converting, by the device, the position coordinates of the first device in the global coordinate system into position coordinates of the first device in a user coordinate system; transmitting the converted position coordinates of the first device in the user coordinate system to the second device; and displaying the position of the first device on the second device based on the converted position coordinates of the first device in the user coordinate system.

Abstract: Methods, systems and kits for quantum-optimized cross-backend software development are provided. According to at least one aspect of the present embodiments, a method for building quantum optimization algorithms that can run on quantum hardware is provided. The method includes receiving an input comprising a user-defined problem and at least one pre-defined Variational Quantum Algorithm (VQA) statement and converting the received input into a workflow. The method also includes obtaining an abstract Variational Quantum Algorithm (VQA) representation based on the workflow and creating a compiled, target-optimized backend specific quantum circuit based on the abstract VQA representation and returning a structured, contextual and indexable output, wherein the output comprises an optimization result and additional metadata.

Abstract: A storage device updates optimal parameters associated with a Thermal Region Tag (TRT). A controller on the storage device assigns a TRT to blocks programmed at a given temperature range and updates an optimal TRT parameters by obtaining a set of representative wordlines and a set of indicative wordlines for a block assigned to the TRT. The controller performs a bit error rate (BER) estimation on indicative wordlines in the set until a valid indicative wordline is found. The controller determines whether a BER Estimation Scan (BES) check is to be performed when the valid indicative wordline is found. In performing the BES check, the controller performs the BER estimation on representative wordlines in the set until a valid representative wordline is found. When a valid representative wordline is found, the controller obtains the optimal TRT parameter and updates the optimal TRT parameter.

Abstract: A storage device updates optimal parameters associated with a Thermal Region Tag (TRT). A controller on the storage device assigns a TRT to blocks programmed at a given temperature range and updates an optimal TRT parameters by obtaining a set of representative wordlines and a set of indicative wordlines for a block assigned to the TRT. The controller performs a bit error rate (BER) estimation on indicative wordlines in the set until a valid indicative wordline is found. The controller determines whether a BER Estimation Scan (BES) check is to be performed when the valid indicative wordline is found. In performing the BES check, the controller performs the BER estimation on representative wordlines in the set until a valid representative wordline is found. When a valid representative wordline is found, the controller obtains the optimal TRT parameter and updates the optimal TRT parameter.

Abstract: The present invention relates to a cosmetic ink application device which functions by producing a region as an alignment marker on human skin and detecting the region to align an applicator with the skin, and a method thereof.

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A method for remote control of at least one non-ultra wide band (nUWB) device in a space by an electronic device is provided. The method includes identifying a position using at least one ultra wideband (UWB) anchor in the space, determining a field of view based on the position of the electronic device in the space, identifying the at least one nUWB device within the field of view, and establishing communication with the at least one nUWB device.

Abstract: Adsorbent compositions are described. The adsorbent compositions include a metal oxide/mixed metal oxide component, a zeolite component, a metal carbonate component, and optionally a binder. The adsorbent compositions provide high inorganic and organic chloride capacity, controlled acidity, low polymerization/green oil formation, improved hydrothermal stability and mechanical properties including crush strength, increased adsorbent life, and fewer plugging byproduct-formation concerns. Methods of removing organic chlorides and inorganic chlorides from a process fluid using the adsorbent compositions are also described.

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A system and method, wherein the method includes: (a) receiving a fluid comprising a process reagent for an assay and nucleic acid material from a sample into a fluid pathway coupled to an array of wells, wherein the array of wells is defined within a substrate and each well in the array of wells extends vertically into a planar surface of the substrate; (b) distributing the fluid along the fluid pathway and into wells of the array of wells; and (c) distributing a liquid immiscible with the fluid comprising the process reagent and nucleic acid material along the fluid pathway upon positive pressure generation by a pump of a flow control system in communication with an inlet to the fluid pathway, thereby displacing said fluid along the fluid pathway and into wells of the array of wells and preventing contents of each well from transferring to adjacent wells.

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.

Abstract: A data storage device has a controller that instructs a memory to read memory cells using a number of different read voltage levels and then selects the read voltage level that provides the best read. Instead of sending individual commands for each of the different read voltage levels, the controller sends a single command that specifies an initial read voltage level and a voltage shift, and the memory automatically increments the read voltage level by the voltage shift for each read.

Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).

Abstract: A method for verifying a drone included in an industrial Internet of Things (IIoT) system, using a petri-net modeling is disclosed. In an embodiment, the method includes a step of modeling the IIoT system as a hierarchical petri-net (modeling step); and a step of verifying whether the drone has security vulnerability on the basis of the hierarchical petri-net model (verification step), wherein the verification step can determine that a drone has security vulnerability when at least one of a plurality of determination factors provided as places to the hierarchical petri-net model determines that the drone is operating abnormally.

Abstract: A data storage device has a controller that instructs a memory to read memory cells using a number of different read voltage levels and then selects the read voltage level that provides the best read. Instead of sending individual commands for each of the different read voltage levels, the controller sends a single command that specifies an initial read voltage level and a voltage shift, and the memory automatically increments the read voltage level by the voltage shift for each read.

Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.

Abstract: A system and method, wherein the system includes: an array of wells defined at a substrate, each well including an open surface and a well cavity and a fluid delivery module including a fluid pathway through which fluid flow is controlled along a fluid path in a direction parallel to the broad face of the substrate; and wherein the method includes: generating a set of genetic complexes within individual wells of the array of wells.