Abstract: The gasoline blending is a critical aspect in oil refinery operations. There are multiple blending rules in prior art to predict the chemical or physical property of the blend. But none of the prior method focuses on obtaining the best blending rule for each feature used in creating the soft-sensor. A method and system for generating a soft-sensor for getting desired property of a blend by optimizing a set of blending rules for each feature used for creating soft-sensor have been provided using data from individual components of the blend. The method comprises automated soft-sensor creation using multiple data sources. Further, the method involves finding best blending rule for each feature used for building the soft-sensor or the blending model to predict property of the blend. The soft-sensor developed using data of components used for blending is adapted to predict mixture or blend property with limited tuning.

Abstract: This disclosure relates generally to method and system to monitor and control continuous ultrafiltration (UF) process units. In real time, continuous operation of UF to handle variating concentration in feed stream is tedious and complex. The UF plant system receives a plurality of input data configured to UF process units and from the real time data outliers are removed and missing values are imputed. The prediction module predicts a volumetric concentration factor (VCF) value and a throughput value by selecting a model from a model repository. The optimization module optimizes the VCF value, and the throughput value based on a plurality of optimal variables recommended for a given feed concentration. The UF plant system controls the VCF value and the throughput value for a predefined period of a prediction horizon based on a plurality of trajectory profiles recommended for the feed flow rate, the pressure data, and a feed concentration.

Abstract: Trajectory optimization is process of designing a trajectory of operating variables that optimizes measure of performance while satisfying a set of constraints, when the system moves from one state to another. It is very necessary to achieve optimization in real time. A system and method for real-time trajectory optimization has been provided. The trajectory optimization of a process can be performed in any dynamical automated system. The system is configured to optimize the trajectory in both online and offline mode. In the online mode, the system optimizes the trajectory of the process in real-time. The system has the ability to handle both machine learning and deep learning based time series models along with first principles based models represented by ordinary/partial differential equation or differential algebraic equation based dynamic models of the process to estimate process variables given the disturbance profile and the actuation profile of manipulated variables.

Abstract: Process control of continuous production of biomolecules is a major challenge due to complex nature of processes and time scales of operations involved. Availability of key process variables in real-time is one of main requirements. This disclosure relates to a processor implemented method of controlling a continuous bioprocessing plant which includes at least one of: receiving, an input data associated with one or more equipments; generating, by a recipe builder, a sequence of unit operations to determine at least one job order based on the at least input data; obtaining, a control decision associated with a control parameter based on the at least one job order; communicating, via the middleware, the control decision associated with the control parameter to the PLC; and executing, by a control system of the PLC, the control decision on a unit equipment to control: (i) a continuous bioprocessing train, and (ii) an individual unit operation.

Abstract: State of the art techniques used for Flue Gas Desulpharization (FGD) process monitoring fail to comprehend the relationship between various process parameters, which is crucial in determining the performance of a FGD process being monitored. The disclosure herein generally relates to industrial process monitoring, and, more particularly, to a method and system for performance optimization of Flue Gas Desulphurization (FGD) Unit. The system identifies Key Performance Indicators (KPIs) associated with the process being monitored, and identifies parameters associated with each KPI. This information is used to generate several predictive models, from which a predictive model having the highest value of composite model score amongst the predictive models is selected as the predictive model for processing the input data, which is then used to perform optimization of the FGD process.

Abstract: Monitoring and analysis of plurality of operations in mining and mineral processing is critical to achieve optimized performance. Existing tools are specific to one or other individual operations and this individuality introduces limitations for end to end monitoring of entire mining to mineral processing operations. Method and system for online monitoring and optimization of mining and mineral processing operations providing an integrated approach utilizing short-term mining plan data, information generated using established drill and blast design software, simulation models of fragmentation, crushing, screening, grinding and flotation to arrive at an optimized charge plan and set points for controllers is disclosed. The proposed method and system improves key performance indicators such as cost of mining operations, specific energy consumption in comminution circuit, maximizes yield of desired particle size, and maximizes grade and recovery of mineral of interest while considering operational constraints.

Abstract: This disclosure relates to a method and system for regime-based process optimization of various assets of industrial manufacturing and process plants or units. Operating regimes of assets are identified and a regime similarity score of each asset is computed from regime sequences of integrated industrial data and compared with a given threshold to identify regimes of operation. Operating regimes are matched with regimes of regime database and industrial assets and similar operating regimes are group together. Process optimization is carried out for each group of industrial assets to identify optimum settings in order to maximize output or minimize loss/cost considering process and equipment constraints. Anomalies are analyzed in the unmatched operating regimes and a diagnosis is carried out to identify the root cause for any detected anomalies. Remaining useful life of components in the assets with unmatched operating regimes is estimated to ensure component reliability and to prevent failure.

Abstract: The disclosure generally relates to methods and systems for determining multi-column chromatography process configuration for capturing antibodies. Conventional approaches for design of MCC configuration are limited to rule based, either driven by UV spectroscopic measurements or by performing number of experiments, which involves a lot of material costs and time utilization. The present disclosure solves the technical problem of identifying the operational conditions that optimized the MCC process and the MCC configuration. A multi-objective optimization function defined with one or more decision variables associated with the operating conditions is considered to determine the optimal MCC configuration, while satisfying purification goals. The one or more key performance measures of the MCC process comprises a productivity, a capacity utilization, a product yield, and a product purity.

Abstract: This disclosure relates to optimizing an operation of an equipment by a neural network based optimizer is provided. The method include receiving, information associated with at least one equipment instance (j) as an input at a predefined sequence of timestamps; training, a plurality of simulation models for each equipment instance to obtain a function (fj); processing, the external input parameters (et) to obtain a fixed-dimensional vector and passed as an input to obtain an vector (it); generating, a modified (it) from the output vector (it) based on a domain constraint value; computing, a reward (rt) based on (i) the function (fj), (ii) the modified (it), (iii) the external input parameters (et), and (iv) a reward function (Rj); and iteratively performing the steps of processing, generating, and computing reward (rt) for a series of subsequent equipment instances after expiry of the predefined sequence of timestamps associated with a first equipment instance.

Abstract: Monitoring and analysis of plurality of operations in mining and mineral processing is critical to achieve optimized performance. Existing tools are specific to one or other individual operations and this individuality introduces limitations for end to end monitoring of entire mining to mineral processing operations. Method and system for online monitoring and optimization of mining and mineral processing operations providing an integrated approach utilizing short-term mining plan data, information generated using established drill and blast design software, simulation models of fragmentation, crushing, screening, grinding and flotation to arrive at an optimized charge plan and set points for controllers is disclosed. The proposed method and system improves key performance indicators such as cost of mining operations, specific energy consumption in comminution circuit, maximizes yield of desired particle size, and maximizes grade and recovery of mineral of interest while considering operational constraints.