Patents by Inventor Vishwesh Patil

Vishwesh Patil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID DELIVERY TO THE CENTRAL NERVOUS SYSTEM
    Publication number: 20240167031
    Abstract: Featured are polymeric nanocarriers (e.g., PLGA nanoparticles) with encapsulated nucleic acid (e.g., an antisense oligonucleotide) for delivery (e.g., intrathecally) to the central nervous system. These polymeric nanocarriers are useful in the treatment of central nervous system disorders. They are capable of delivering their cargo (e.g., an antisense oligonucleotide) in higher amounts, for a longer period of time, and into deeper regions of the brain than a free or unformulated antisense oligonucleotide. The efficient delivery and distribution of antisense oligonucleotides results in reducing the number of administrations and patient compliance and improves patient experience.
    Type: Application
    Filed: March 31, 2022
    Publication date: May 23, 2024
    Inventors: Hasan M. Yildiz, Mandana Bornapour, Paul Peng, Vishwesh A. Patil, Brian R. Simler, William F. Kiesman
  • Stable Dual Variable Domain Immunoglobulin Protein Formulations
    Publication number: 20200385456
    Abstract: The invention provides stable aqueous formulations comprising an Aqueous Stable Dual Variable Domain Immunoglobulin (AS-DVD-Ig) protein. The invention also provides stable lyophilized formulations comprising a Lyophilized Stable Dual Variable Domain Immunoglobulin (LS-DVD-Ig) protein.
    Type: Application
    Filed: January 17, 2020
    Publication date: December 10, 2020
    Inventors: Michael Siedler, Vineet Kumar, Ravi Chari, Sonal Saluja, Vishwesh Patil
  • Stable Dual Variable Domain Immunoglobulin Protein Formulations
    Publication number: 20170210796
    Abstract: The invention provides stable aqueous formulations comprising an Aqueous Stable Dual Variable Domain Immunoglobulin (AS-DVD-Ig) protein. The invention also provides stable lyophilized formulations comprising a Lyophilized Stable Dual Variable Domain Immunoglobulin (LS-DVD-Ig) protein.
    Type: Application
    Filed: November 4, 2016
    Publication date: July 27, 2017
    Inventors: Michael SIEDLER, Vineet KUMAR, Ravi CHARI, Sonal SALUJA, Vishwesh PATIL
  • REAGENTS AND METHODS FOR BISPECIFIC ANTIBODY-BASED BINDING OF TARGET MOLECULES
    Publication number: 20140186850
    Abstract: The invention provides methods for delivery of payloads to targets in samples using non-sterically hindered complexes. The invention further provides reagents and kits for practicing the methods of the invention. The invention also provides methods for preparation of reagents for use in the methods of the invention.
    Type: Application
    Filed: December 19, 2013
    Publication date: July 3, 2014
    Applicant: AKRIVIS TECHNOLOGIES, LLC
    Inventors: Joel Berniac, Peter Donovan, Ban-An Khaw, Vishwesh Patil
  • STABLE DUAL VARIABLE DOMAIN IMMUNOGLOBULIN PROTEIN FORMULATIONS
    Publication number: 20140161817
    Abstract: The invention provides stable aqueous formulations comprising an Aqueous Stable Dual Variable Domain Immunoglobulin (AS-DVD-Ig) protein. The invention also provides stable lyophilized formulations comprising a Lyophilized Stable Dual Variable Domain Immunoglobulin (LS-DVD-Ig) protein.
    Type: Application
    Filed: November 1, 2013
    Publication date: June 12, 2014
    Inventors: Michael Siedler, Vineet Kumar, Ravi Chari, Sonal Saluja, Vishwesh Patil