Abstract: An ultrasonically vibrating snare wire at the end of an elongate flexible waveguide can fit through an endoscope inserted in a patient's intestine. The wire loop can be extended past the distal end of the endoscope to grasp a polyp projecting from the intestinal wall. While the wire is vibrating at ultrasonic frequency, the loop is closed. This cuts and coagulates the tissue to stop bleeding. The ultrasonic cutting is more localized than electrocautery for more precise excision.