Patents by Inventor Viswanathan Sasisekharan

Viswanathan Sasisekharan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agents for influenza neutralization
    Patent number: 10947300
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: March 16, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • AGENTS FOR INFLUENZA NEUTRALIZATION
    Publication number: 20200123234
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Application
    Filed: November 6, 2019
    Publication date: April 23, 2020
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • Agents for influenza neutralization
    Patent number: 10538578
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: January 21, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • AGENTS FOR INFLUENZA NEUTRALIZATION
    Publication number: 20190062407
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Application
    Filed: April 23, 2018
    Publication date: February 28, 2019
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • Agents for influenza neutralization
    Patent number: 9982037
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: May 29, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • AGENTS FOR INFLUENZA NEUTRALIZATION
    Publication number: 20170306003
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Application
    Filed: May 15, 2017
    Publication date: October 26, 2017
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • Agents for influenza neutralization
    Patent number: 9683030
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 20, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • Engineered polypeptide agents for targeted broad spectrum influenza neutralization
    Patent number: 9572861
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: February 21, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, S. Raguram, Viswanathan Sasisekharan, Vidya Subramanian
  • ENGINEERED POLYPEPTIDE AGENTS FOR TARGETED BROAD SPECTRUM INFLUENZA NEUTRALIZATION
    Publication number: 20160317612
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Application
    Filed: April 8, 2016
    Publication date: November 3, 2016
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, S. Raguram, Viswanathan Sasisekharan, Vidya Subramanian
  • Engineered polypeptide agents for targeted broad spectrum influenza neutralization
    Patent number: 9334309
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: May 10, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, S. Raguram, Viswanathan Sasisekharan, Vidya Subramanian
  • Decoy influenza therapies
    Patent number: 8815522
    Abstract: The present invention provides umbrella-topology glycan decoys. The present invention provides systems and methods treating influenza infection utilizing inventive umbrella-topology glycan decoys. The present invention provides methods for identifying novel umbrella-topology glycan decoys.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: August 26, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan
  • ENGINEERED POLYPEPTIDE AGENTS FOR TARGETED BROAD SPECTRUM INFLUENZA NEUTRALIZATION
    Publication number: 20140206603
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Application
    Filed: January 24, 2014
    Publication date: July 24, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, S. Raguram, Viswanathan Sasisekharan, Vidya Subramanian
  • Engineered polypeptide agents for targeted broad spectrum influenza neutralization
    Patent number: 8637456
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: January 28, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, S. Raguram, Viswanathan Sasisekharan, Vidya Subramanian
  • AGENTS FOR INFLUENZA NEUTRALIZATION
    Publication number: 20130302348
    Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.
    Type: Application
    Filed: March 14, 2013
    Publication date: November 14, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: S. Raguram, Viswanathan Sasisekharan, Venkataramanan Soundararajan, Ram Sasisekharan, Vidya Subramanian, Kannan Tharakaraman
  • ENGINEERED POLYPEPTIDE AGENTS FOR TARGETED BROAD SPECTRUM INFLUENZA NEUTRALIZATION
    Publication number: 20110201547
    Abstract: The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
    Type: Application
    Filed: January 27, 2011
    Publication date: August 18, 2011
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Venkataramanan Soundararajan, Sasi Raguram, Viswanathan Sasisekharan
  • Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto
    Publication number: 20100061990
    Abstract: The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
    Type: Application
    Filed: August 14, 2007
    Publication date: March 11, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan
  • Decoy Influenza Therapies
    Publication number: 20100004195
    Abstract: The present invention provides umbrella-topology glycan decoys. The present invention provides systems and methods treating influenza infection utilizing inventive umbrella-topology glycan decoys. The present invention provides methods for identifying novel umbrella-topology glycan decoys.
    Type: Application
    Filed: January 2, 2009
    Publication date: January 7, 2010
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan
  • Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto
    Publication number: 20090269342
    Abstract: The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
    Type: Application
    Filed: January 2, 2009
    Publication date: October 29, 2009
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan
  • HEMAGGLUTININ POLYPEPTIDES, AND REAGENTS AND METHODS RELATING THERETO
    Publication number: 20090081193
    Abstract: The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
    Type: Application
    Filed: January 3, 2008
    Publication date: March 26, 2009
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan
  • Hemagglutinin polypeptides, and reagents and methods relating thereto
    Publication number: 20080241918
    Abstract: The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.
    Type: Application
    Filed: August 14, 2007
    Publication date: October 2, 2008
    Inventors: Ram Sasisekharan, Karthik Viswanathan, Aarthi Chandrasekaran, Rahul Raman, Aravind Srinivasan, S. Raguram, Viswanathan Sasisekharan