Patents by Inventor Vit Karafiat

Vit Karafiat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phospholipid derivatives and their use as medicaments
    Patent number: 11414443
    Abstract: The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I; in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: August 16, 2022
    Assignees: USTAV MOLEKULARNI GENETIKY AV CR, V.V.I., SMART BRAIN S.R.O.
    Inventors: Michal Dvorak, Marta Dvorakova, Vit Karafiat, Jan Stursa, Lukas Werner, Lucie Janeckova
  • PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS
    Publication number: 20200102333
    Abstract: The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula 1; in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 2, 2020
    Inventors: Michal DVORAK, Marta DVORAKOVA, Vit KARAFIAT, Jan STURSA, Lukas WERNER, Lucie JANECKOVA
  • Myb-transformed blood cells and their use for active ingredient screening
    Publication number: 20040106093
    Abstract: The invention relates to transformed blood cells and their use for active ingredient screening. The field of application of the invention are the pharmaceutical industry and medicine.
    Type: Application
    Filed: January 13, 2004
    Publication date: June 3, 2004
    Inventors: Petr Bartunek, Michal Dvorak, Martin Zenke, Vit Karafiat