Abstract: A method of generating a computer-based observable model of an implantable repair material secured to a patient is provided. The method includes processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor. The method also includes indicating an implantable repair material and a fixation for securing the implantable repair material to the patient and indicating a distribution of the fixation about the implantable repair material. The method also includes generating an observable model of the implantable repair material secured to the patient on a display operably associated with the computing device. The observable model depicts the indicated distribution of the fixation about the implantable repair material.

Abstract: The present disclosure describes kits for surgical repair of soft tissue defects, including hernias. The kits include any combination of components selected from an implantable sheet, at least one loop tie, a delivery tool, a positioner, a rolling device, and a insertion member. Packaging for the kits and/or components and methods of using the kits and/or components are also provided.

Abstract: A method, apparatus and program for completing a knowledge graph from a plurality of predicates and associated entities, the predicates each providing information on a relationship between a pair of entities, the method comprising the steps of: receiving an input comprising the plurality of predicates and associated entities; searching an axiom database and identifying predicates among the plurality of predicates that are equivalent to one another, or inverses of one another; identifying further predicates that are related to one another, using the axiom database and identified predicates; and embedding the identified predicates and associated entities into a vector space to complete the knowledge graph.

Abstract: A method of generating a computer-based observable model of an implantable repair material secured to a patient is provided. The method includes processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor. The method also includes indicating an implantable repair material and a fixation for securing the implantable repair material to the patient and indicating a distribution of the fixation about the implantable repair material. The method also includes generating an observable model of the implantable repair material secured to the patient on a display operably associated with the computing device. The observable model depicts the indicated distribution of the fixation about the implantable repair material.

Abstract: The present disclosure describes kits for surgical repair of soft tissue defects, including hernias. The kits include any combination of components selected from an implantable sheet, at least one loop tie, a delivery tool, a positioner, a rolling device, and a insertion member. Packaging for the kits and/or components and methods of using the kits and/or components are also provided.

Abstract: A method of generating a computer-based observable model of an implantable repair material secured to a patient is provided. The method includes processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor. The method also includes indicating an implantable repair material and a fixation for securing the implantable repair material to the patient and indicating a distribution of the fixation about the implantable repair material. The method also includes generating an observable model of the implantable repair material secured to the patient on a display operably associated with the computing device. The observable model depicts the indicated distribution of the fixation about the implantable repair material.

Abstract: A system for calculating similarities between drugs and using the similarities to extrapolate side effects of a specified drug comprising: a similarity-computation apparatus configured to use open data to compute similarities between drugs, with: a data integration module configured to obtain data related to a set of drugs from a plurality of open data sources and to integrate the data to generate RDF triples; an RDF module configured to store an RDF graph of the RDF triples: and a similarity calculation module configured to retrieve a list of all the drugs present in the RDF graph and to calculate the similarity of each drug with every other drug in the RDF graph, for storage in a similarity database; and a side effect determining apparatus configured to extrapolate side effects of a specified drug from open data related to the set of drugs, with: a connection to the similarity database; a user interface configured to allow a user to specify a drug from the set of drugs; a neighbours ranking module configure

Abstract: A method, apparatus and program for completing a knowledge graph from a plurality of predicates and associated entities, the predicates each providing information on a relationship between a pair of entities, the method comprising the steps of: receiving an input comprising the plurality of predicates and associated entities; searching an axiom database and identifying predicates among the plurality of predicates that are equivalent to one another, or inverses of one another; identifying further predicates that are related to one another, using the axiom database and identified predicates; and embedding the identified predicates and associated entities into a vector space to complete the knowledge graph.

Abstract: A method of generating a computer-based observable model of an implantable repair material secured to a patient is provided. The method includes processing data corresponding to a patient using a computing device including a processor and a memory storing a software application executable by the processor. The method also includes indicating an implantable repair material and a fixation for securing the implantable repair material to the patient and indicating a distribution of the fixation about the implantable repair material. The method also includes generating an observable model of the implantable repair material secured to the patient on a display operably associated with the computing device. The observable model depicts the indicated distribution of the fixation about the implantable repair material.

Abstract: A discovery informatics system is arranged to produce a graph based on a corpus of textual documents, the graph including documents in the corpus as nodes, with links between the nodes annotated by connecting concepts, the connecting concepts directly and indirectly connecting the documents.

Abstract: Apparatus for calculating term co-occurrence scores for use in a natural language processing method, where a term is a word or a group of consecutive words, in which apparatus at least one text document is analysed and pairs of terms, from terms which occur in the document, are ascribed respective co-occurrence scores to indicate an extent of an association between them, comprises sentence sequence processing means (280) and co-occurrence score set calculation means (230), wherein: the sentence sequence processing means (280) are operable to for each of all possible sequences of sentences in a document, where the minimum number of sentences in a sequence is one and the maximum number of sentences in a sequence has a predetermined value, determine a weighting value w which is a decreasing function of the number of sentences in the sentence sequence; determine a sentence sequence count value, based on the sum of all the determined weighting values; obtain a document term count value, where the document term cou

Abstract: A system for calculating similarities between drugs and using the similarities to extrapolate side effects of a specified drug comprising: a similarity-computation apparatus configured to use open data to compute similarities between drugs, with: a data integration module configured to obtain data related to a set of drugs from a plurality of open data sources and to integrate the data to generate RDF triples; an RDF module configured to store an RDF graph of the RDF triples: and a similarity calculation module configured to retrieve a list of all the drugs present in the RDF graph and to calculate the similarity of each drug with every other drug in the RDF graph, for storage in a similarity database; and a side effect determining apparatus configured to extrapolate side effects of a specified drug from open data related to the set of drugs, with: a connection to the similarity database; a user interface configured to allow a user to specify a drug from the set of drugs; a neighbours ranking module configure

Abstract: A query mediator arranged to query a polyglot data tier of data stores, each data store adopting a data model and the polyglot data tier including at least two different types of data store with differing data models. The query mediator including at least one HTTP API; a catalogue containing metadata for each data store; and a plurality of adapters, one for each data model. The API receives an incoming query from a client, checks the query against the catalogue to identify a correct data store storing the queried data, and routes the query to an adapter for the correct data store. The adapter transforms the query into a format suitable for use with the data model adopted in the correct data store, for execution by the relevant data store. The API returns the query result to the client in response to the incoming query.