Patents by Inventor Vitaliy V. Nesterenko

Vitaliy V. Nesterenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Birch bark processing and the isolation of natural products from birch bark
    Patent number: 7264184
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: September 4, 2007
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
  • Process for extracting compounds from plants
    Patent number: 7198808
    Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: April 3, 2007
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
  • Birch bark processing and the isolation of natural products from birch bark
    Patent number: 6815553
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: November 9, 2004
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
  • Process for extracting compounds from plants
    Publication number: 20040009242
    Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.
    Type: Application
    Filed: May 9, 2003
    Publication date: January 15, 2004
    Applicant: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
  • Birch bark processing and the isolation of natural products from birch bark
    Patent number: 6634575
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: October 21, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor M. Kolomitsyn, Chris F. Edwardson
  • Methods for manufacturing betulinic acid
    Publication number: 20030073858
    Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.
    Type: Application
    Filed: July 11, 2002
    Publication date: April 17, 2003
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Process for extracting compounds from plants
    Publication number: 20020155177
    Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.
    Type: Application
    Filed: January 17, 2002
    Publication date: October 24, 2002
    Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
  • Process for extracting compounds from plants
    Publication number: 20020114853
    Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.
    Type: Application
    Filed: October 1, 2001
    Publication date: August 22, 2002
    Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
  • Methods for manufacturing betulinic acid
    Patent number: 6407270
    Abstract: The present invention provides a method for preparing an ester of betulin at the 3-position, e.g., betulin-3-acetate, including the selective alcoholysis of a betulin-3,28-diester, e.g., betulin-3,28-diacetate; a method for preparing betulin-3-acetate including (1) acetylating betulin to provide betulin-3,28-diacetate and (2) the alcoholysis of betulin-3,28-diacetate to provide betulin-3-acetate; a method for preparing betulinic acid from betulin-3-acetate including (1) acetylating betulin to provide betulin-3,28-diacetate, (2) the alcoholysis of betulin-3,28-diacetate to provide betulin-3-acetate, (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate, (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate, and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: June 18, 2002
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Birch bark processing and the isolation of natural products from birch bark
    Publication number: 20020070167
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Application
    Filed: February 6, 2002
    Publication date: June 13, 2002
    Applicant: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
  • Birch bark processing and the isolation of natural products from birch bark
    Patent number: 6392070
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Grant
    Filed: August 10, 1999
    Date of Patent: May 21, 2002
    Assignee: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Birch bark processing and the isolation of natural products from birch bark
    Publication number: 20020043577
    Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.
    Type: Application
    Filed: August 23, 2001
    Publication date: April 18, 2002
    Applicant: Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor M. Kolomitsyn, Chris F. Edwardson
  • Methods for manufacturing betulinic acid
    Publication number: 20020028960
    Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.
    Type: Application
    Filed: June 29, 2001
    Publication date: March 7, 2002
    Applicant: Naturtek, LLC, Regents of the University of Minnesota
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Method for manufacturing betulinic acid
    Patent number: 6271405
    Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3 -acetate to provide betulinic acid.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: August 7, 2001
    Assignees: Regents of the University of Minnesota, Naturtek, LLC
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Method for manufacturing betulinic acid
    Publication number: 20010007908
    Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.
    Type: Application
    Filed: January 16, 2001
    Publication date: July 12, 2001
    Applicant: Regents of the University of Minnesota, Naturtek, LLC
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
  • Method for manufacturing betulinic acid
    Patent number: 6232481
    Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.
    Type: Grant
    Filed: January 11, 2000
    Date of Patent: May 15, 2001
    Assignees: Regents of the University of Minnesota, Naturtek, LLC
    Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko