Patents by Inventor Vitaly Grigorievich Paraskevov

Vitaly Grigorievich Paraskevov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing 4-hydroxy-L-isoleucine
    Patent number: 8367382
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: February 5, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Sakayu Shimizu, Jun Ogawa, Makoto Hibi, Vitaly Grigorievich Paraskevov
  • Method for producing 4-hydroxy-L-isoleucine
    Patent number: 8367381
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: February 5, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Sakayu Shimizu, Jun Ogawa, Makoto Hibi, Vitaly Grigorievich Paraskevov
  • Method for producing 4-hydroxy-L-isoleucine
    Patent number: 8273562
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: September 25, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative, Sakayu Shimizu, Jun Ogawa, Makoto Hibi
  • Method for producing an L-amino acid using bacterium of the family with attenuated expression of a gene coding for small RNA
    Patent number: 8227214
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: July 24, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konstantin Vyacheslavovich Rybak, Aleksandra Yurievna Skorokhodova, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Tatyana Viktorovna Leonova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative, Takuji Ueda
  • Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the gene
    Patent number: 8187850
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the ybiV gene.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: May 29, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konstantin Vyacheslavovich Rybak, Marina Evgenievna Sheremet'eva, Aleksandra Yurievna Skorokhodova, Tatyana Viktorovna Leonova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative
  • METHOD FOR PRODUCING 4-HYDROXY-L-ISOLEUCINE
    Publication number: 20120115203
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 10, 2012
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Yury Ivanovich Kozlov, Sakayu Shimizu, Jun Ogawa, Makoto Hibi, Vitaly Grigorievich Paraskevov
  • METHOD FOR PRODUCING 4-HYDROXY-L-ISOLEUCINE
    Publication number: 20120107884
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 3, 2012
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, Sakayu Shimizu, Jun Ogawa, Makoto Hibi
  • METHOD FOR PRODUCING 4-HYDROXY-L-ISOLEUCINE
    Publication number: 20120107883
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Application
    Filed: January 5, 2012
    Publication date: May 3, 2012
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, Sakayu Shimizu, Jun Ogawa, Makoto Hibi
  • METHOD FOR PRODUCING AN L-AMINO ACID USING BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF A GENE CODING FOR SMALL RNA
    Publication number: 20120070865
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 22, 2012
    Inventors: Konstantin Vyacheslavovich Rybak, Aleksandra Yurievna Skorokhodova, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Tatyana Viktorovna Leonova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, Takuji Ueda
  • Method for producing 4-hydroxy-L-isoleucine
    Patent number: 8114651
    Abstract: A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: February 14, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tomohiro Kodera, Sergey Vasilievich Smirnov, Natalia Nikolaevna Samsonova, Veronika Aleksandrovna Kotliarova, Natalia Yurievna Rushkevich, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative, Sakayu Shimizu, Jun Ogawa, Makoto Hibi
  • Method for producing an L-amino acid using bacterium of the family with attenuated expression of a gene coding for small RNA
    Patent number: 8088606
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: January 3, 2012
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konstantin Vyacheslavovich Rybak, Aleksandra Yurievna Skorokhodova, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Tatyana Viktorovna Leonova, Vitaly Grigorievich Paraskevov, Takuji Ueda
  • Method for producing an L-amino acid using a bacterium of the family by inactivating a gene encoding a toxin of a bacterial toxin-antitoxin pair
    Patent number: 7855060
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging the genus Escherichia or Pantoea, wherein said bacterium has attenuated expression of a gene encoding a toxin of a bacterial toxin-antitoxin pair.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: December 21, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Dmitriy Vladimirovich Filippov, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Konstantin Vyacheslavovich Rybak, Marina Evgenievna Sheremeteva, Aleksandra Yurievna Skorokhodova, Vitaly Grigorievich Paraskevov
  • METHOD FOR PRODUCING AN L-AMINO ACID USING BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF A GENE CODING FOR SMALL RNA
    Publication number: 20100311129
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
    Type: Application
    Filed: August 18, 2010
    Publication date: December 9, 2010
    Inventors: Konstantin Vyacheslavovich Rybak, Aleksandra Yurievna Skorokhodova, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Tatyana Viktorovna Leonova, Vitaly Grigorievich Paraskevov, Takuji Ueda
  • Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family With Attenuated Expression of the ybiV Gene
    Publication number: 20100279362
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the ybiV gene.
    Type: Application
    Filed: January 30, 2008
    Publication date: November 4, 2010
    Inventors: Konstantin Vyacheslavovich Rybak, Marina Evgenievna Sheremet'eva, Aleksandra Yurievna Skorokhodova, Tatyana Viktorovna Leonova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov
  • Method for producing an L-amino acid by fermentation using a bacterium having an enhanced ability to utilize glycerol
    Patent number: 7811798
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to have glycerol kinase in which feedback inhibition by fructose-1,6-bisphosphate is desensitized, thereby having enhanced ability to utilize glycerol.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: October 12, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konstantin Vyacheslavovich Rybak, Ekaterina Aleksandrovna Slivinskaya, Marina Evgenievna Sheremet'eva, Yulia Aleksandrovna Ovodova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative
  • Method for producing an L-amino acid using bacterium of the family with attenuated expression of a gene coding for small RNA
    Patent number: 7803584
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: September 28, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Konstantin Vyacheslavovich Rybak, Aleksandra Yurievna Skorokhodova, Elvira Borisovna Voroshilova, Mikhail Markovich Gusyatiner, Tatyana Viktorovna Leonova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov, legal representative, Takuji Ueda
  • Method for producing a non-aromatic L-amino acid using a bacterium of the family having expression of the csrA gene attenuated
    Patent number: 7771976
    Abstract: The present invention provides a method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to attenuate expression of the csrA gene.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: August 10, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Andrey Yurievich Gulevich, Danila Vadimovich Zimenkov, Elena Vitalievna Klyachko, Tatyana Viktorovna Leonova, Yury Ivanovich Koslov, Vitaly Grigorievich Paraskevov, legal representative
  • METHOD FOR PRODUCING AN L-AMINO ACID BY FERMENTATION USING A BACTERIUM HAVING AN ENHANCED ABILITY TO UTILIZE GLYCEROL
    Publication number: 20090317876
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to have glycerol kinase in which feedback inhibition by fructose-1,6-bisphosphate is desensitized, thereby having enhanced ability to utilize glycerol.
    Type: Application
    Filed: June 22, 2009
    Publication date: December 24, 2009
    Inventors: Konstantin Vyacheslavovich Rybak, Ekaterina Aleksandrovna Slivinskaya, Marina Evgenievna Sheremet'eva, Yulia Aleksandrovna Ovodova, Yury Ivanovich Kozlov, Vitaly Grigorievich Paraskevov
  • Method for Producing a Non-Aromatic L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family Having Expression of the csrA Gene Attenuated
    Publication number: 20090239266
    Abstract: The present invention provides a method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to attenuate expression of the csrA gene.
    Type: Application
    Filed: July 31, 2007
    Publication date: September 24, 2009
    Inventors: Andrey Yurievich Gulevich, Danila Vadimovich ZIMENKOV, Elena Vitalievna KLYACHKO, Tatyana Viktorovna LEONOVA, Yury Ivanovich Kozlov, Vitaly Grigorievich PARASKEVOV
  • Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family With Enhanced Expression of the fucPIKUR Operon
    Publication number: 20090209011
    Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to enhance expression of at least one gene of the fucPIKUR operon.
    Type: Application
    Filed: December 7, 2007
    Publication date: August 20, 2009
    Inventors: Konstantin Vyacheslavovich Rybak, Ekaterina Aleksandrovna Slivinskaya, Marina Evgenievna Sheremet'eva, Aleksandra Yurievna Skorokhodova, Vitaly Grigorievich Paraskevov