Abstract: Systems, methods, and software can provide high-accuracy position estimation for mobile user equipment (UE) configured for use within a service area covered by a plurality of radio units, e.g., O-RUs, with known position including coordinates. A channel estimate can be derived for a channel between a given UE and each of a plurality of radio units based on a sounding reference signal (SRS) received from the UE and used to select a subset of the radio units. The shortest delay can be calculated for the given UE to each O-RU in the subset, forming a set of uplink-time-difference-of-arrival (UL-TDOA) measurements; position of the given UE in the service area can be estimated based on the UL-TDOA measurements. The O-RU synchronization error can be estimated for each O-RU in the subset using estimated positions of the given UE and corresponding UL-TDOA measurements.