Patents by Inventor Vitor Manuel CORRELO DA SILVA

Vitor Manuel CORRELO DA SILVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9579417
    Abstract: The present application discloses cell-adhesive gellan gum spongy-like hydrogels that are able to entrap/encapsulate adherent cells, which spread within the material, maintaining their phenotype and remaining viable and proliferative. The methodology used to obtain these materials involves hydrogel preparation, freezing, freeze-drying and re-hydration with a saline solution with cells and with/without bioactive molecules. No pre and/or post functionalization of the spongy-like hydrogels with cell adhesive features, as used for other hydrogels, is used. The cell adhesive character of these materials, not observed in hydrogels, is in part explained by their physical properties, between sponges and hydrogels, dissimilar from the precursor hydrogels. The physical properties that are mainly different are the morphology, microstructure, water content, and mechanical performance.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: February 28, 2017
    Assignee: ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING AND CELL BASED TECHNOLOGIES AND THERAPIES-A4TEC
    Inventors: Lucilia Pereira Da Silva, Mariana Teixeira Cerqueira, Rui Pedro Romero Amandi De Sousa, Alexandra Margarida Pinto Marques, Vitor Manuel Correlo Da Silva, Rui Luis Goncalves Dos Reis
  • Publication number: 20160325017
    Abstract: The present application discloses cell-adhesive gellan gum spongy-like hydrogels that are able to entrap/encapsulate adherent cells, which spread within the material, maintaining their phenotype and remaining viable and proliferative. The methodology used to obtain these materials involves hydrogel preparation, freezing, freeze-drying and re-hydration with a saline solution with cells and with/without bioactive molecules. No pre and/or post functionalization of the spongy-like hydrogels with cell adhesive features, as used for other hydrogels, is used. The cell adhesive character of these materials, not observed in hydrogels, is in part explained by their physical properties, between sponges and hydrogels, dissimilar from the precursor hydrogels. The physical properties that are mainly different are the morphology, microstructure, water content, and mechanical performance.
    Type: Application
    Filed: April 9, 2014
    Publication date: November 10, 2016
    Inventors: Lucilia PEREIRA DA SILVA, Mariana TEIXEIRA CERQUEIRA, Rui Pedro ROMERO AMANDI DE SOUSA, Alexandra Margarida PINTO MARQUES, Vitor Manuel CORRELO DA SILVA, Rui Luis GONCALVES DOS REIS