Abstract: The administration of the drug, containing defibrotide as the active ingredient, in the case of acute renal insufficiencies accompanied by a thrombotic microangiopathy, permits the evolution of the clinical situation towards the chronicity to be stopped and, in a number of cases, a complete remission to be obtained.

Abstract: Portable hemodialysis apparatus which can be used for dialysis and/or ultrafiltration, or hemoperfusion. Separate circuits are provided for blood and for the ultrafiltrate and the dialysis solution. The blood circuit includes a pump in which the flexible tube is periodically throttled, causing blood to be drawn from the patient and advanced under pressure through the blood circuit. A similar pump is included in the circuit for the dialysis solution. The output side of the latter pump is selectively connectable either with the inlet of the dialyzer or with an ultrafiltrate collection station, while the input side of the latter pump is selectively connectable with the outlet of the dialyzer either through the dialysis liquid supply tank or directly via a shunt line. A lighter auxiliary tank is also provided for temporary freedom of movement with respect to the normal supply tank.