Patents by Inventor Vittorio Lucchini

Vittorio Lucchini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST
    Publication number: 20200339622
    Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.
    Type: Application
    Filed: July 15, 2020
    Publication date: October 29, 2020
    Applicant: DIPHARMA FRANCIS S.r.l.
    Inventors: Gabriele RAZZETTI, Anna IULIANO, Luca GIANNOTTI, Grazia IANNUCCI, Emanuele ATTOLINO, Vittorio LUCCHINI, Renzo GRAZIOSI
  • Method for preparing a farnesoid X receptor agonist
    Patent number: 10752654
    Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: August 25, 2020
    Assignee: Dipharma Francis S.R.L.
    Inventors: Gabriele Razzetti, Anna Iuliano, Luca Giannotti, Grazia Iannucci, Emanuele Attolino, Vittorio Lucchini, Renzo Graziosi
  • METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST
    Publication number: 20190106455
    Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.
    Type: Application
    Filed: April 3, 2017
    Publication date: April 11, 2019
    Applicant: DIPHARMA FRANCIS S.r.l.
    Inventors: Gabriele RAZZETTI, Anna IULIANO, Luca GIANNOTTI, Grazia IANNUCCI, Emanuele ATTOLINO, Vittorio LUCCHINI, Renzo GRAZIOSI
  • Process for the purification of 2-phenyl-2-methyl-propanoic acid derivatives
    Patent number: 9334223
    Abstract: Process for the preparation of 2-phenyl-2-methyl propanoic acid derivatives, useful as intermediates in the preparation of fexofenadine hydrochloride.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: May 10, 2016
    Assignee: Dipharma Francis S.r.l.
    Inventors: Pietro Allegrini, Vittorio Lucchini, Davide Rossi, Mauro Mittino, Gabriele Razzetti
  • PROCESS FOR THE PURIFICATION OF 2-PHENYL-2-METHYL-PROPANOIC ACID DERIVATIVES
    Publication number: 20150099899
    Abstract: Process for the preparation of 2-phenyl-2-methyl propanoic acid derivatives, useful as intermediates in the preparation of fexofenadine hydrochloride.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 9, 2015
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Pietro ALLEGRINI, Vittorio LUCCHINI, Davide ROSSI, Mauro MITTINO, Gabriele RAZZETTI
  • PROCESS FOR THE PREPARATION OF (R)-PRAMIPEXOLE
    Publication number: 20120253047
    Abstract: The invention relates to a novel process for the preparation of (R)-2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazole, or a salt thereof.
    Type: Application
    Filed: April 19, 2012
    Publication date: October 4, 2012
    Applicant: Dipharma S.p.A.
    Inventors: Pietro ALLEGRINI, Gabriele Razzetti, Vittorio Lucchini
  • Intermediates for the preparation of pramipexole
    Patent number: 8203002
    Abstract: Intermediates useful for the preparation of pramipexole and the use thereof in such synthesis.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: June 19, 2012
    Assignee: Dipharma S.p.A.
    Inventors: Graziano Castaldi, Alberto Bologna, Pietro Allegrini, Gabriele Razzetti, Vittorio Lucchini
  • Process for the preparation of dexlansoprazole
    Patent number: 8198455
    Abstract: Process for the preparation of (R)-2-[[[3-methyl-4(2,2,2-trifluoroethoxy)-2-piridyl]methyl]sulfinyl]benzimidazole (Dexlansoprazole) and new intermediates useful in its preparation.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: June 12, 2012
    Assignee: Dipharma Francis S.r.l.
    Inventors: Emanuele Attolino, Vittorio Lucchini
  • Process for the preparation of pyridine-methylsulfinyl compounds
    Patent number: 7790891
    Abstract: A process for the preparation of a compound of formula (I), or a salt thereof, wherein Q is ?CR8— or ?N—; and R1-R8 are as herein defined; comprising the reaction of a compound of formula (II), or a salt thereof, wherein Q, R1-R7 are as herein defined; with a reducing agent selected from a trivalent phosphorous compound, an oxidizable solvent and a sulfonic acid chloride; and, if desired, the conversion of a compound of formula (I) to another compound of formula (I) or a salt thereof.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: September 7, 2010
    Assignee: Dipharma Francis S.R.L.
    Inventors: Pietro Allegrini, Marcello Rasparini, Gabriele Razzetti, Simone Mantegazza, Vittorio Lucchini, Alberto Bologna
  • INTERMEDIATES FOR THE PREPARATION OF PRAMIPEXOLE
    Publication number: 20100222595
    Abstract: Intermediates useful for the preparation of pramipexole and the use thereof in such synthesis.
    Type: Application
    Filed: May 10, 2010
    Publication date: September 2, 2010
    Applicant: DIPHARMA S.p.A.
    Inventors: Graziano CASTALDI, Alberto Bologna, Pietro Allegrini, Gabriele Razzetti, Vittorio Lucchini
  • Intermediates for the preparation of pramipexole
    Patent number: 7741490
    Abstract: Intermediates useful for the preparation of pramipexole and the use thereof in such synthesis.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: June 22, 2010
    Assignee: Dipharma S.p.A.
    Inventors: Graziano Castaldi, Alberto Bologna, Pietro Allegrini, Gabriele Razzetti, Vittorio Lucchini
  • PROCESS FOR THE PREPARATION OF DEXLANSOPRAZOLE
    Publication number: 20100125143
    Abstract: Process for the preparation of (R)-2-[[[3-methyl-4(2,2,2-trifluoroethoxy)-2-piridyl]methyl]sulfinyl]benzimidazole (Dexlansoprazole) and new intermediates useful in its preparation.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Applicant: DIPHARMA FRANCIS S.r.I.
    Inventors: Emanuele ATTOLINO, Vittorio Lucchini
  • Process for the preparation of pyridine-methylsulfinyl compounds
    Publication number: 20090076277
    Abstract: A process for the preparation of a compound of formula (I), or a salt thereof, wherein Q is ?CR8— or ?N—; and R1-R8 are as herein defined; comprising the reaction of a compound of formula (II), or a salt thereof, wherein Q, R1-R7 are as herein defined; with a reducing agent selected from a trivalent phosphorous compound, an oxidizable solvent and a sulfonic acid chloride; and, if desired, the conversion of a compound of formula (I) to another compound of formula (I) or a salt thereof.
    Type: Application
    Filed: October 29, 2007
    Publication date: March 19, 2009
    Applicant: DIPHARMA FRANCIS S.R.L.
    Inventors: Pietro ALLEGRINI, Marcello RASPARINI, Gabriele RAZZETTI, Simone MANTEGAZZA, Vittorio LUCCHINI, Alberto BOLOGNA
  • Process for the preparation of phenyltetrazole derivatives
    Patent number: 7385062
    Abstract: A process for the preparation of phenyltetrazole derivatives of formula (II) wherein R and Y are as defined in the disclosure, by direct ortho-metallation of (tetrazol-5-?l)benzene. The compounds of formula (II) are useful intermediates for the preparation of angiotensin II antagonists.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: June 10, 2008
    Assignee: Dipharma S.p.A.
    Inventors: Graziano Castaldi, Pietro Allegrini, Gabriele Razzetti, Alberto Bologna, Marcello Rasparini, Vittorio Lucchini
  • PROCESS FOR THE PREPARATION OF BENZO [D] ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF
    Publication number: 20080081914
    Abstract: A process for the preparation of benzo[d]isoxazol-3-yl-methanesulfonic acid of formula (I), or a salt thereof, and the intermediates thereof, useful as an intermediate in the preparation of zonisamide.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 3, 2008
    Applicant: DIPHARMA S.P.A.
    Inventors: GABRIELE RAZZETTI, SIMONE MANTEGAZZA, GRAZIANO CASTALDI, PIETRO ALLEGRINI, VITTORIO LUCCHINI, ALBERTO BOLOGNA
  • Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof
    Patent number: 7291742
    Abstract: A process for the preparation of benzo[d]isoxazol-3-yl-methanesulfonic acid of formula (I), or a salt thereof, and the intermediates thereof, useful as an intermediate in the preparation of zonisamide.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: November 6, 2007
    Assignee: Dipharma S.p.A.
    Inventors: Gabriele Razzetti, Simone Mantegazza, Graziano Castaldi, Plietro Allegrini, Vittorio Lucchini, Alberto Bologna
  • Intermediates for the preparation of pramipexole
    Publication number: 20070191439
    Abstract: Intermediates useful for the preparation of pramipexole and the use thereof in such synthesis.
    Type: Application
    Filed: March 11, 2005
    Publication date: August 16, 2007
    Applicant: DIPHARMA S.P.A.
    Inventors: Graziano Castaldi, Alberto Bologna, Pietro Allegrini, Gabriele Razzetti, Vittorio Lucchini
  • PROCESS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTIC COMPOUNDS
    Publication number: 20070093540
    Abstract: A process for the preparation of angiotensin II antagonists and novel intermediates useful for the synthesis thereof.
    Type: Application
    Filed: October 19, 2006
    Publication date: April 26, 2007
    Applicant: DIPHARMA S.p.A.
    Inventors: Pietro ALLEGRINI, Gabriele Razzetti, Roberto Rossi, Vittorio Lucchini, Simone Mantegazza, Marcello Rasparini
  • Process for the preparation of benzylimidazole derivatives
    Patent number: 7164029
    Abstract: A process for the preparation of benzylimidazole derivatives useful as intermediates for preparation of losartan, novel intermediates for their preparation and a process for the preparation of losartan.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: January 16, 2007
    Assignee: Dipharma S.p.A.
    Inventors: Pietro Allegrini, Gabriele Razzetti, Graziano Castaldi, Vittorio Lucchini
  • Process for the preparation of phenyltetrazole derivatives
    Publication number: 20060183916
    Abstract: A process for the preparation of phenyltetrazole derivatives of formula (II) wherein R and Y are as defined in the disclosure, by direct ortho-metallation of (tetrazol-5-?l)benzene. The compounds of formula (II) are useful intermediates for the preparation of angiotensin II antagonists.
    Type: Application
    Filed: July 30, 2004
    Publication date: August 17, 2006
    Inventors: Graziano Castaldi, Pietro Allegrini, Gabriele Razzetti, Alberto Bologna, Marcello Rasparini, Vittorio Lucchini