Abstract: The present invention relates to the pharmaceutical compositions of lectin proteins and its use for the prevention, treatment and cure of inflammation, including inflammatory disease. The invention specifically relates to the pharmaceutical compositions for topical application comprising lectin proteins and its use for prevention, treatment and cure of inflammation due to chemotherapy and/or radiotherapy. The lectin may comprise an amino acid sequence having sequence of SEQ ID NO: 1 or at least 70% homology to SEQ ID NO: 1.

Abstract: Described techniques and systems can identify a request to transfer one or more computer-implemented resources associated with a first computer-implemented account to a second computer-implemented account, the one or more computer-implemented resources at least in part managed through a service accessible by at least one entity selected to consider the request, the service implemented separately from another service to manage access to the one or more computer-implemented resources. Also, the techniques and systems can confirm the at least one entity approved the request to transfer the one or more computer-implemented resources associated with the first computer-implemented account, and transfer the one or more computer-implemented resources to the second computer-implemented account.

Abstract: The present invention relates to recombinant proteins, compositions and methods of stabilization thereof. The invention specifically relates to the stable recombinant protein of SEQ ID NO: 1 and composition comprising recombinant protein of SEQ ID NO: 1. The invention further relates to method of preparing, storing and stabilizing recombinant protein of SEQ ID NO: 1 and its composition for longer shelf life.

Abstract: A method and system are devised for improved Interconnecting ring transition from open to closed state. The Interconnecting ring comprises a Media redundancy Interconnection Manager, MIM and at least three Media redundancy Interconnection Clients, MICs, the MIM being in Link Check, LC, mode. When the Interconnecting ring is in open state, and upon the MIM receiving a first one of first INLNK_UP MRP frames sent by one of the MICs, the MIM starts sending periodic second INLNK_UP MRP frames, changes to Check Interconnection, Interconnection Closed State, CHK_IC, state and the Interconnecting ring to closed state, if the MIM receives one of the second INLNK_UP MRP frames, or a second one of the first INLNK_UP MRP frames.

Abstract: A blimp includes a circular disk-shaped envelope filled with a lighter-than-air gas. A gondola is affixed to an underside of the envelope and is disposed at a region directly below a center point of the circle defined by the intersection of the envelope and the horizontal plane. The gondola includes: a horizontally-disposed elongated circuit board that functions as a structural member of the gondola; and a vertical member extending upwardly from the circuit board and having a top that is attached to the underside of the envelope. A thrusting mechanism is affixed to the gondola and is configured to generate thrust. An electronics suite is disposed on and electrically coupled to the circuit board and includes a blimp processor configured to generate control signals that control the thrusting mechanism. A battery is affixed to the gondola and provides power to the electronics suit and the thrusting mechanism.

Abstract: The present invention relates to stable formulations of recombinant proteins. The invention specifically relates to the formulations of recombinant lectins derived from Sclerotium rolfsii lectin. The formulation comprises recombinant lectin derived from Sclerotium rolfsii lectin and a pharmaceutically acceptable excipient. The invention also relates to the stable liquid and/or lyophilized formulations comprising recombinant lectins derived from Sclerotium rolfsii lectin.

Abstract: The present invention relates to an intranasal composition, particularly once weekly intranasal composition comprising methylcobalamin and at least one gelling agent and a process for preparation thereof.

Abstract: Exemplary embodiments of the present disclosure are directed towards a system and method for making strategies and generating customized reports based on users in real-time, comprising: computing device comprising strategy making and customized report generating module configured to deploy agents in interaction layer where users interact with customized reports. Strategy making and customized report generating module configured to capture variety of information related to users and knowledge base database configured to store information required to generate customized reports in different ways for users on computing device. The knowledge base database resides strategy processor configured to decide strategies. The strategy processor configured to decide structural properties for insights and send structural properties to knowledge base database.

Abstract: Exemplary embodiments of the present disclosure are directed towards a system for explaining actions taken in real-time on event stream, comprising: a computing device comprises a data analyzation and precise decision module configured to take inputs, the data analyzation and precise decision module configured to analyze the inputs and implements decisions on the computing device, the data analyzation and precise decision module also configured to send a written narrative and give an explanation about the plurality of decisions to a user in a natural language; and a database configured to house the most of the information known to the data analyzation and precise decision module, the database comprises an action table to implement any decision being taken in the data analyzation and precise decision module and updates the action table based on the user responds to the data analyzation and precise decision module.

Abstract: Exemplary embodiments of the present disclosure are directed towards a system for generating dynamic visualizations and narrations of digital data, comprising: a computing device comprises a dynamic data visualization and narration module, whereby the dynamic data visualization and narration module comprises a metadata extraction module configured to process the digital data on the computing device, an insight generator configured to filter out all unwanted weightages based on the data's domain, a reducer configured to take account of user inputs and weights generated at that point by a preference engine and the reducer also configured to take the account of user inputs and the reducer is configured to decide which insight is relevant enough to be shown to the user, visualizations generated on the computing device based on dynamic factors or features of the data and patterns in the data on which the insight is formed.

Abstract: This invention relates to pharmaceutical formulations comprising 1-(2-thien-2?-yl-2-oxo-ethyl)-3-(methanesulfonyl hydrazine carbonyl) pyridinium, its pharmaceutically acceptable salts, salt-cocrystals and co-crystals, particularly 1-(2-thien-2?-yl-2-oxo-ethyl)-3-5(methanesulfonyl hydrazine carbonyl) pyridinium chloride. The formulations are suitable for oral administration and also comprise a permeability enhancer or a suitable base or a mixture thereof. The formulations of this invention are for treating diseases associated with advanced glycation end products.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for generating and providing composition effect tutorials for creating and editing digital content based on a metadata composite structure. For example, the disclosed systems can generate and/or access a metadata composite structure that includes nodes corresponding to composition effects applied to a digital content item, where a given node can include location information indicating where a composition effect is applied relative to a digital content item. The disclosed systems can further generate a tutorial to guide a user to implement a selected composition effect by identifying composition effects of nodes that correspond to a location selected within a composition interface and presenting instructions for a particular composition effect.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for generating and providing composition effect tutorials for creating and editing digital content based on a metadata composite structure. For example, the disclosed systems can generate and/or access a metadata composite structure that includes nodes corresponding to composition effects applied to a digital content item, where a given node can include location information indicating where a composition effect is applied relative to a digital content item. The disclosed systems can further generate a tutorial to guide a user to implement a selected composition effect by identifying composition effects of nodes that correspond to a location selected within a composition interface and presenting instructions for a particular composition effect.

Abstract: The present invention relates to an intranasal composition, particularly once weekly intranasal composition comprising methylcobalamin and at least one gelling agent and a process for preparation thereof.

Abstract: A blimp includes a circular disk-shaped envelope filled with a lighter-than-air gas. A gondola is affixed to an underside of the envelope and is disposed at a region directly below a center point of the circle defined by the intersection of the envelope and the horizontal plane. The gondola includes: a horizontally-disposed elongated circuit board that functions as a structural member of the gondola; and a vertical member extending upwardly from the circuit board and having a top that is attached to the underside of the envelope. A thrusting mechanism is affixed to the gondola and is configured to generate thrust. An electronics suite is disposed on and electrically coupled to the circuit board and includes a blimp processor configured to generate control signals that control the thrusting mechanism. A battery is affixed to the gondola and provides power to the electronics suit and the thrusting mechanism.

Abstract: The present invention relates to topical pharmaceutical compositions comprising Apremilast in an amount of about 0.1 to 5% w/w of the total composition and one or more pharmaceutically acceptable excipients and process for their preparation. The present invention further relates to method for treatment of skin diseases using topical pharmaceutical compositions comprising Apremilast.

Abstract: The present invention relates to novel pyridinium compounds, their isomers, steroisomers, atropisomers, conformers, tautomers, polymorphs, hydrates and solvates. The present invention also encompasses process for preparing novel compounds and pharmaceutical composition of said compounds. The invention further relates to the use of the above mentioned compounds for the preparation of medicament for use as pharmaceuticals.

Abstract: Disclosed herein are pharmaceutical compositions for nasal administration comprising tapentadol, their preparation and their use in the treatment of pain.

Abstract: Provided herein are novel fused pyrimidinone derivatives of Formula I and synthetic intermediates that are useful in preparing the compounds of formula (I). Further provided herein is a method for preparation of a compound of formula (I) or intermediates, a pharmaceutical composition comprising a compound of formula (I), and use of a compound of formula (I).