Patents by Inventor Vivian Bykerk

Vivian Bykerk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING PAIN IN SUBJECTS WITH RHEUMATOID ARTHRITIS
    Publication number: 20200399380
    Abstract: The present disclosure relates to the use of an anti-IL6 receptor antibody for treating unacceptable pain in subjects with rheumatoid arthritis. Subjects with unacceptable pain can have, e.g., refractory pain or strict refractory pain.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 24, 2020
    Inventors: Susan Boklage, Toshio Kimura, Stefano Fiore, Gregory St John, Wenhui Wei, Vivian Bykerk
  • Methods of diagnosing and treating rheumatoid arthritis and osteoarthritis
    Patent number: 7776313
    Abstract: The invention provides a novel cell that is a precursor of a fibroblast-like synovial cell. The novel cell is a circulating synovial tissue cell that stains positive for collagen, CD34, CD45, prolyl 4-hydroxylase and CD14. The invention also relates to methods of diagnosing or monitoring rheumatoid arthritis and/or osteoarthritis using gene expression profiles, protein expression profiles, and/or protein phosphorylation profiles of different cell types, including the novel precursor, CD3+ cells, synovial tissue fibroblast-like synovial cells and fibrocytes. The invention also includes methods to identify substances to treat or prevent rheumatoid arthritis and/or osteoarthritis.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: August 17, 2010
    Assignees: University Health Network, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Eleanor Fish, Carole Galligan, Kathy Siminovitch, Omar Perez, Edward Keystone, Vivian Bykerk
  • Methods of diagnosing and treating rheumatoid arthritis and osteoarthritis
    Publication number: 20070292881
    Abstract: The invention provides a novel cell that is a precursor of a fibroblast-like synovial cell. The novel cell is a circulating synovial tissue cell that stains positive for collagen, CD34, CD45, prolyl 4-hydroxylase and CD14. The invention also relates to methods of diagnosing or monitoring rheumatoid arthritis and/or osteoarthritis using gene expression profiles, protein expression profiles, and/or protein phosphorylation profiles of different cell types, including the novel precursor, CD3+ cells, synovial tissue fibroblast-like synovial cells and fibrocytes. The invention also includes methods to identify substances to treat or prevent rheumatoid arthritis and/or osteoarthritis.
    Type: Application
    Filed: May 25, 2007
    Publication date: December 20, 2007
    Inventors: Eleanor Fish, Carole Galligan, Kathy Siminovitch, Omar Perez, Edward Keystone, Vivian Bykerk