Patents by Inventor Vlada Melnikova

Vlada Melnikova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EARLY ASSESSMENT OF MECHANISM OF ACTION AND EFFICACY OF ANTI-CANCER THERAPIES USING MOLECULAR MARKERS IN BODILY FLUID
    Publication number: 20180087114
    Abstract: Provided is a method of determining responsiveness of a subject to a treatment for a cancer. Also provided is a method of determining treatment recommendations for a subject with cancer. Additionally provided is a method of treating a subject with cancer.
    Type: Application
    Filed: March 4, 2016
    Publication date: March 29, 2018
    Applicant: Trovagene, Inc.
    Inventors: Vlada Melnikova, Mark G. Erlander
  • Synthesis and enrichment of nucleic acid sequences
    Patent number: 9725755
    Abstract: The present disclosure relates to the enrichment of target nucleic acid sequences present in low-abundance relative to corresponding non-target or reference nucleic acid sequence in a sample. In particular, the methods allow for a substantially greater level of detection sensitivity of target sequence by orders of magnitude enrichment of a low-abundance sequence.
    Type: Grant
    Filed: September 3, 2016
    Date of Patent: August 8, 2017
    Assignee: Trovagene, Inc.
    Inventors: Jason Poole, Saege Handcock, Karena Kosco, Vlada Melnikova, Peter Croucher, Tim Lu, Mark Erlander, Errin Samuelsz
  • SYNTHESIS AND ENRICHMENT OF NUCLEIC ACID SEQUENCES
    Publication number: 20170009276
    Abstract: The present disclosure relates to the enrichment of target nucleic acid sequences present in low-abundance relative to corresponding non-target or reference nucleic acid sequence in a sample. In particular, the methods allow for a substantially greater level of detection sensitivity of target sequence by orders of magnitude enrichment of a low-abundance sequence.
    Type: Application
    Filed: September 3, 2016
    Publication date: January 12, 2017
    Applicant: Trovagene, Inc.
    Inventors: Jason Poole, Saege Handcock, Karena Kosco, Vlada Melnikova, Peter Croucher, Tim Lu, Mark Erlander, Errin Samuelsz
  • SYNTHESIS AND ENRICHMENT OF NUCLEIC ACID SEQUENCES
    Publication number: 20160273022
    Abstract: The present disclosure relates to the enrichment of target nucleic acid sequences present in low-abundance relative to corresponding non-target or reference nucleic acid sequence in a sample. In particular, the methods allow for a substantially greater level of detection sensitivity of target sequence by orders of magnitude enrichment of a low-abundance sequence.
    Type: Application
    Filed: October 20, 2014
    Publication date: September 22, 2016
    Inventors: Jason Poole, Saege Handcock, Karena Kosco, Vlada Melnikova, Peter Croucher, Tim Lu, Mark Erlander, Errin Samuelsz
  • DETECTION OF NUCLEIC ACIDS IN URINE
    Publication number: 20160002740
    Abstract: Provided are methods of determining whether a subject comprises a target nucleic acid sequence that is 51-110 nucleotides in length. Also provided are methods of monitoring a condition or treatment effect in a subject.
    Type: Application
    Filed: August 20, 2015
    Publication date: January 7, 2016
    Inventors: Cecile Rose Vibat, Vlada Melnikova, Charles Rodi