Patents by Inventor Vladas Algirdas Bumelis

Vladas Algirdas Bumelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing interferon alpha 5
    Patent number: 8709757
    Abstract: A process for producing an interferon alpha 5 (IFNa5) protein by expression in an IFNa5 producing Escherichia coli host cell, wherein incorporation of an extra methionine residue in the N-terminal end of the polypeptide chain is minimized as well as the generation of its oxidized species is disclosed. The IFNa5 protein can be purified by an efficient process to render a biologically active IFNa5.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: April 29, 2014
    Assignee: Digna Biotech, S.L.
    Inventor: Vladas Algirdas Bumelis
  • METHOD FOR PRODUCING INTERFERON ALPHA 5
    Publication number: 20120309057
    Abstract: A process for producing an interferon alpha 5 (IFNa5) protein by expression in an IFNa5 producing Escherichia coli host cell, wherein incorporation of an extra methionine residue in the N-terminal end of the polypeptide chain is minimized as well as the generation of its oxidised species is disclosed. The IFNa5 protein can be purified by an efficient process to render a biologically active IFNa5.
    Type: Application
    Filed: January 31, 2011
    Publication date: December 6, 2012
    Applicant: DIGNA BIOTECH, S.L.
    Inventor: Vladas Algirdas Bumelis