Abstract: The present invention is a novel blood or plasma panel with utility in assessing chronic liver disease severity in a point-of-care setting. The scoring system exhibits 97.2% correlation to previously assigned Child Pugh scores and does not require clinical assessment beyond laboratory testing.

Abstract: A vortex flowmeter includes a flow tube having a first end and a second end. A shedder bar is disposed within the flow tube between the first end and the second end. The shedder bar is configured to generate vortices in fluid flowing through the flow tube. At least one sensor is operably coupled to an external surface of the flow tube and is configured to detect individual deformations of the flow tube resulting from vortices inside the flow tube.

Abstract: A vortex flowmeter includes a flow tube having a first end and a second end. A shedder bar is disposed within the flow tube between the first end and the second end. The shedder bar is configured to generate vortices in fluid flowing through the flow tube. At least one sensor is operably coupled to an external surface of the flow tube and is configured to detect individual deformations of the flow tube resulting from vortices inside the flow tube.

Abstract: Embodiments of the invention are directed to a method of inhibiting proliferation of a cell induced by asTF that includes exposing the proliferating cell to an inhibitor of asTF at a concentration sufficient to attenuate asTF induced proliferation. In an embodiment, the proliferating cell is a cancer cell such as a breast cancer cell. The inhibitor of asTF may be an anti-asTF antibody, such as a monoclonal antibody or an antibody fragment, a small molecule, a peptide, nucleic acid, and combinations thereof.

Abstract: A vortex flow meter includes a vortex responsive assembly having a diaphragm. The diaphragm seals a base end of the assembly to form an isolation chamber. The assembly is adapted to seal an opening in a sidewall of a flow passage. Support struts preferably protrude from the assembly into the flow passage. In one configuration, a vortex oscillation sensor plate has a proximate edge supported on the diaphragm and an opposite distal edge that is unsupported. The vortex oscillation sensor plate has upstream and downstream edges preferably supported by the support struts. A pivoting strut extends along a central region of the vortex oscillation sensor plate. The pivoting strut extends through the diaphragm. The pivoting strut transfers vortex oscillations to a sensor. An electronic transmitter circuit receives a sensor output and provides an output related to flow of the fluid.

Abstract: A vortex flow meter includes a vortex responsive assembly having a diaphragm. The diaphragm seals a base end of the assembly to form an isolation chamber. The assembly is adapted to seal an opening in a sidewall of a flow passage. Support struts preferably protrude from the assembly into the flow passage. In one configuration, a vortex oscillation sensor plate has a proximate edge supported on the diaphragm and an opposite distal edge that is unsupported. The vortex oscillation sensor plate has upstream and downstream edges preferably supported by the support struts. A pivoting strut extends along a central region of the vortex oscillation sensor plate. The pivoting strut extends through the diaphragm. The pivoting strut transfers vortex oscillations to a sensor. An electronic transmitter circuit receives a sensor output and provides an output related to flow of the fluid.

Abstract: A method, apparatus and computer memory are provided for recognizing an audio fingerprint of an unknown audio recording. A database stores a plurality of audio recording identifiers corresponding to a plurality of known audio recordings, where the audio recording identifiers are organized by variation information about the audio recordings. A processor searches a database and identifies at least one of the audio recording identifiers corresponding to the audio fingerprint, where the audio fingerprint includes variation information of the unknown audio recording.

Abstract: A method, apparatus and computer memory are provided for generating an audio fingerprint of an audio recording. A memory stores stable frequency family data corresponding to a plurality of stable frequency families. A processor curve fits audio recording data to at least one of the stable frequency families, extracts at least one variation from the curve fitted audio recording data, and creates the audio fingerprint of the audio recording from the at least one variation.

Abstract: A new circulating form of soluble human tissue factor was identified. This new form of human tissue factor appears to be the result of alternative splicing and is therefore referred to as “alt-hTF.” Alt-hTF mRNA was detected in a cell line, HL-60. The cDNA region encoding the entire open reading frame of alt-hTF was cloned. The sequence encoding the alt-hTF mature peptide was expressed in bacteria. alt-hTF consists of the first 166 amino acids of membrane bound TF, and a 40 amino acid C-terminal region unique to alt-hTF. Alt-hTF is likely to be a useful target for compounds to inhibit clotting and to treat disorders associated with elevated TF. It may also be useful as a target for antibodies selectively reactive with alt-hTF, to remove it from the circulation for treatment of clotting or other disorders associated with elevated or abnormal levels of TF, including thrombotic conditions, cardiovascular disorders, DVT, DIC, and possibly metastatic cancers.

Abstract: A system and method are provided for matching a track set from a digital audio recording to metadata relating to the recording. Track duration data is obtained for the track set, and the track duration data is rounded. A search is performed for matching records in a first database based on the rounded track duration data, each resulting matching record having an identifier. Track duration data is retrieved from a second database based on the identifiers associated with the matching records. If more than one matching record is found, the track duration data retrieved from the second database is compared to the track duration data obtained for the track set to find a best matching record of in the second database. Metadata contained in the best matching record of the second database is output.

Abstract: A new circulating form of soluble human tissue factor was identified. This new form of human tissue factor appears to be the result of alternative splicing and is therefore referred to as “alt-hTF.” Alt-hTF mRNA was detected in a cell line, HL-60. The cDNA region encoding the entire open reading frame of alt-hTF was cloned. The sequence encoding the alt-hTF mature peptide was expressed in bacteria. alt-hTF consists of the first 166 amino acids of membrane bound TF, and a 40 amino acid C-terminal region unique to alt-hTF. Alt-hTF is likely to be a useful target for compounds to inhibit clotting and to treat disorders associated with elevated TF. It may also be useful as a target for antibodies selectively reactive with alt-hTF, to remove it from the circulation for treatment of clotting or other disorders associated with elevated or abnormal levels of TF, including thrombotic conditions, cardiovascular disorders, DVT, DIC, and possibly metastatic cancers.