Patents by Inventor Vladimir Borisovich Malyshev

Vladimir Borisovich Malyshev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing a biological material for use in ophthalmology
    Patent number: 6037144
    Abstract: A collagen containing substrate comprising cattle basal membrane is conditioned by incubating the membranes in a mixture of pepsin, hyaluronidase and acetic acid and separating the collagen from the mixture. The mixture can include pepsin, hyaluronidase and a 0.5M solution of acetic acid in 1:1:10 proportions. The incubation is conducted for about 10 hours at about 45.degree. C. After incubation, collagen is separated from the mixture by centrifuging at a speed of 5000 to 30000 rpms for about 30 minutes. The collagen is mixed with polymerizable monomer and polymerized to form a gel that can be ground to form an intraocular or contact lens.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: March 14, 2000
    Assignee: Staar Surgical AG
    Inventors: Svyatoslav Nikolayevich Fedorov, Sergei Nikolayevich Bagrov, Yevgeny Viktorovich Larionov, Vladimir Borisovich Malyshev
  • Method of preparing a biological material for use in ophthalmology
    Patent number: 5936256
    Abstract: A collagen containing substrate comprising cattle basal membrane is conditioned by incubating the membranes in a mixture of pepsin, hyaluronidase and acetic acid and separating the collagen from the mixture. The mixture can include pepsin, hyaluronidase and a 0.5 M solution of acetic acid in 1:1:10 proportions. The incubation is conducted for about 10 hours at about 45.degree. C. After incubation, collagen is separated from the mixture by centrifuging at a speed of 5000 to 30000 rpms for about 30 minutes. The collagen is mixed with polymerizable monomer and polymerized to form a gel that can be ground to form an intraocular or contact lens.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: August 10, 1999
    Assignee: Staar Surgical AG
    Inventors: Svyatoslav Nikolayevich Fedorov, Sergei Nikolayevich Bagrov, Yevgeny Viktorovich Larionov, Vladimir Borisovich Malyshev
  • Method of preparing a biological material for use in ophthalmology
    Patent number: 5856120
    Abstract: A collagen containing substrate comprising cattle basal membrane is conditioned by incubating the membranes in a mixture of pepsin, hyaluronidase and acetic acid and separating the collagen from the mixture. The mixture can include pepsin, hyaluronidase and a 0.5M solution of acetic acid in 1:1:10 proportions. The incubation is conducted for about 10 hours at about 45.degree. C. After incubation, collagen is separated from the mixture by centrifuging at a speed of 5000 to 30000 rpms for about 30 minutes. The collagen is mixed with polymerizable monomer and polymerized to form a gel that can be ground to form an intraocular or contact lens.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: January 5, 1999
    Assignee: Staar Surgical Company, Inc.
    Inventors: Svyatoslav Nikolayevich Fedorov, Sergei Nikolayevich Bagrov, Yevgeny Viktorovich Larionov, Vladimir Borisovich Malyshev