Patents by Inventor Vladimir D. Axelrod

Vladimir D. Axelrod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Replicative RNA-based amplification/detection systems
    Patent number: 5620851
    Abstract: This invention relates to the use of functional reporter molecules in the detection and measurement of targets in a sample. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target.
    Type: Grant
    Filed: October 17, 1994
    Date of Patent: April 15, 1997
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Vladimir D. Axelrod, Fred R. Kramer, Paul M. Lizardi, Donald R. Mills
  • Replicative RNA-based amplification/detection systems
    Patent number: 5356774
    Abstract: This invention relates to the use of functional reporter molecules in the detection and measurement of nucleic acid sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target nucleic acid sequence.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: October 18, 1994
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Vladimir D. Axelrod, Fred R. Kramer, Paul M. Lizardi, Donald R. Mills