Patents by Inventor Vladimir G. Beylin

Vladimir G. Beylin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C1-Symmetric Bisphospine Ligands and Their Use in the Asymmetric Synthesis of Pregabalin
    Publication number: 20090124820
    Abstract: Materials and Methods for preparing (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid and structurally related compounds via enantioselective hydrogenation of prochiral olefins are disclosed. The methods employ novel chiral catalysts, which include C1-symmetric bisphosphine ligands bound to transition metals.
    Type: Application
    Filed: January 14, 2009
    Publication date: May 14, 2009
    Inventors: Jian Bao, Vladimir G. Beylin, Derek Greene, Garrett S. Hoge, William Kissel, Mark Eugene Marlatt, Derek Andrew Pflum, He-Ping Wu
  • Process for preparing chiral [[(2-bromoethyl)-amino]methyl]-nitro-1H-imidazol-1-ethanol and related compounds
    Patent number: 5543527
    Abstract: Chiral compounds useful as radiosensitizers or chemosensitizers having the formula ##STR1## wherein X is halogen or ##STR2## intermediates used to prepare these compounds, and a novel process to prepare these compounds are described.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: August 6, 1996
    Assignees: British Technoloyg Group Limited, Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Anthony D. Sercel, Howard D. H. Showalter, Gerald E. Adams, Edward M. Fielden, Matthew A. Naylor, Ian J. Stratford
  • Process for preparing chiral [[(2-bromoethyl)-amino]methyl]-2-nitro-1H-imidazol-1-ethanol and related compounds
    Patent number: 5481000
    Abstract: Chiral compounds useful as radiosensitizers or chemosensitizers having the formula ##STR1## wherein X is halogen or ##STR2## intermediates used to prepare these compounds, and a novel process to prepare these compounds are described.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: January 2, 1996
    Assignee: Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Anthony D. Sercel, Howard D. H. Showalter, Gerald E. Adams, Edward M. Fielden, Matthew A. Naylor, Ian J. Stratford
  • Processes for the preparation of benzo(chalcogeno)(4,3,2-cd)indazoles and intermediates thereof
    Patent number: 4806654
    Abstract: Improved processes for producing substituted benzo(chalcogeno)[4,3,2-cd] indazoles. The processes produce compounds in higher yields and of greater purity by using a novel sequence of acylation chemistry and easily removed protecting groups. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.
    Type: Grant
    Filed: February 11, 1988
    Date of Patent: February 21, 1989
    Assignee: Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Om P. Goel, Anthony D. Sercel, Howard D. H. Showalter
  • Process for the preparation of 2,3,4,5-tetrafluorobenzoyl acetates
    Patent number: 4689423
    Abstract: An improved process for the preparation of methyl 2,3,4,5-tetrafluorobenzoylacetate is described. The process is for intermediates that lead to trifluoroquinolinic acids which in turn are used to produce antibacterial agents of the difluoro quinolinecarboxylic acid type. The process runs at room temperature, uses a safe and inexpensive base, and can be conveniently scaled up for manufacturing purposes.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: August 25, 1987
    Assignee: Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Om P. Goel
  • Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones
    Patent number: 4672129
    Abstract: An improved process for producing anthra[1,9-cd]-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.
    Type: Grant
    Filed: May 5, 1986
    Date of Patent: June 9, 1987
    Assignee: Warner-Lambert Company
    Inventors: Vladimir G. Beylin, Om P. Goel, H.D. Hollis Showalter